28 research outputs found
Treatment outcomes of drug-resistant pulmonary tuberculosis under programmatic management of multidrug-resistant tuberculosis, at tertiary care center in Mumbai
No full textBackground: This study was undertaken to analyze the clinical profile and treatment outcome in pulmonary drug-resistant tuberculosis (TB) patients under programmatic management of multidrug-resistant tuberculosis (PMDT) at a tertiary care center in Mumbai. Methodology: A retrospective study was conducted at PMDT site of a tertiary care hospital. The data of 194 pulmonary multidrug-resistant (MDR) TB patients diagnosed at our hospital or prediagnosed patients referred to our hospital were meticulously reviewed to study demography, baseline drug susceptibility to first- and second-line drugs, treatment outcomes, comorbidities, and adverse drug reactions (ADRs). Results: Out of 194 patients, 48.4% (68 cured + 26 treatment completed) were successfully treated, 22 (11.3%) failed on therapy, 39 (20.15%) patients died, 23 (11.8%) defaulted, 26 (13.4%) completed treatment with outcomes unknown, 13 (6.7%) were transferred out and in 3 patients (1.5%) treatment was stopped due to ADRs. Most common ADRs were gastrointestinal 32 (16.4%) and psychiatric 37 (19%). However, there was no statistical significance between the prevalence of ADRs and unfavorable outcomes. Most common comorbidities were GERD 27 (40.2%) and diabetes mellitus 22 (32.8%). Conclusion: Baseline drug susceptibility testing (DST) with rapid diagnostic tests, performing DST for second-line drugs, i.e., fluoroquinolones and aminoglycoside and modification of treatment regimen based on the same at start of MDR treatment has prime importance. Early detection of ADR's and comorbidities and their prompt treatment are also equally important
Conscious Quantum Gravity Theory
No full textTitle: Conscious Quantum Gravity Theory (CQGT): Integrating Consciousness into the Fabric of Reality
Author: Aniket Girish Waghmare
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Abstract: The search for a unifying theory that reconciles quantum mechanics and general relativity has remained elusive for over a century. In this paper, we propose a novel hypothesis: that consciousness is not an emergent property of neural complexity, but rather a fundamental, non-local field with quantum and gravitational characteristics. Termed the Conscious Quantum Gravity Theory (CQGT), this framework posits consciousness as a primary field interacting with both space-time curvature and quantum wave functions, thereby offering a new pathway toward a unified theory of everything.
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1. Introduction
Quantum mechanics and general relativity are the two pillars of modern physics. Yet, despite their individual successes, these theories have proved fundamentally incompatible when applied at the extremes of black holes and the Big Bang. The core contradiction lies in the probabilistic nature of quantum physics versus the deterministic geometry of general relativity. Numerous approaches such as string theory, loop quantum gravity, and M-theory have attempted to bridge the gap, but none have produced a testable, widely accepted theory.
This paper introduces a third component potentially missing from the current physical models: consciousness. We argue that consciousness may be a fundamental force or field that coexists with the known forces of nature and plays a role in the very structure of the universe.
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2. Theoretical Basis
2.1 Consciousness as a Non-Local Field
Consciousness is here proposed to be a field ("C-field") with intrinsic quantum properties:
It exists independently of biological substrates.
It is non-local and can influence spatially separated systems (echoing quantum entanglement).
It may carry an energetic signature akin to mass, thus interacting gravitationally.
2.2 The Observer Effect Revisited
In quantum mechanics, the observer plays a mysterious but critical role in collapsing wavefunctions. If the observer's consciousness is itself a quantum field, this might explain the discontinuity between superposition and observed outcomes.
2.3 Interaction with Gravity
We propose that the C-field interacts with space-time via a modified form of the Einstein Field Equations:
G_{\mu\nu} + C_{\mu\nu} = 8\pi G T_{\mu\nu}
Where C_{\mu\nu} represents the energetic and informational impact of the consciousness field on space-time geometry.
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3. Addressing Unification Roadblocks
Challenge CQGT Implication
Incompatibility of quantum theory and gravity The C-field provides a mediating layer of coherence
Lack of dark matter/energy explanation C-field energy may constitute a measurable portion of these phenomena
Measurement problem in quantum mechanics Observer consciousness as a quantum-gravitational entity resolves this
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4. Predictions and Testability
Modified Double Slit Experiments: Involving coherent human intention may demonstrate C-field influence on photon behavior.
Neural-Quantum Interaction: Advanced neuroimaging could detect quantum coherence in brain microtubules (as per Penrose-Hameroff model).
Cosmological Signatures: Consciousness-based anisotropies may exist in the cosmic microwave background or gravitational wave spectrum.
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5. Implications
Unified Theory of Everything: Consciousness becomes the linking principle across all physical laws.
Death and Continuity of Self: If consciousness is fundamental and non-local, individual awareness may persist beyond physical death.
Technology: Future tech may allow for interfacing with the C-field to influence physical reality directly (e.g., healing, communication, transport).
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6. Conclusion
The Conscious Quantum Gravity Theory (CQGT) suggests a paradigm shift in our understanding of the universe: that consciousness is not a byproduct, but a building block of reality. Integrating this field into our theoretical models may resolve long-standing paradoxes in physics and provide a coherent, unified framework for understanding existence at all scales.
This theory invites rigorous exploration, both theoretically and experimentally, and offers a potential bridge not only between quantum mechanics and gravity but also between science and experience.
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Contact: Aniket Girish Waghmare
[+919819672521 / [email protected]]
Keywords: Consciousness, Quantum Gravity, Unified Theory, Observer Effect, C-field, Dark Matter, Conscious Univers
Stridor Post-Pneumonectomy - “The Post-pneumonectomy Syndrome”
No full textWe report a case of a 33 year old lady who presented to
our department with complaints of breathlessness and
stridor. On enquiry she gave history of right
pneumonectomy for right main bronchus carcinoid 15
years ago. Chest X-ray as initial investigation showed
homogenous opacity in right hemothorax with
mediastinal shift to right. Computed tomography of
thorax showed post-pneumonectomy status with left
lower lobe bronchus compression between the aorta
and main pulmonary artery with post obstructive
overinflation of left lower lobe. Spirometry was
suggestive of an obstructive abnormality. Diagnosis of
post-pneumonectomy syndrome was made and patient
was treated with inhaled corticosteroids and inhaled
long acting beta2 agonist
Pulmonary Talco-silicosis in a Balloon Making Industry Worker
No full textWe report a case of a thirty eight year old lady, working in balloon making industry. She was referred to us in view of incidental chest X-ray changes found during preoperative pulmonary evaluation. She was asymptomatic from respiratory point of view. Chest Xray was suggestive of bilateral reticulonodular opacities. HRCT thorax revealed interstitial lung disease. Spirometry was suggestive of restrictive abnormality. Subsequently the powder which patient used to instill in balloon before inflating was brought for analysis which revealed 32.73% silica. Hence diagnosis of talco-silicosis was made, in the absence of any other cause for lung involvement
Comparative assessment of the frying performance of palm olein and sunflower oil during deep-fat frying of Indian battered food products
No full textThe present study evaluates the frying performance of palm olein and sunflower oil during deep-fat frying of Indian snacks. Changes in parameters such as free fatty acids (FFA), peroxide value (PV), p-anisidine value (AV), total oxidation as TOTOX value (TV), dienes, and trienes value together with colour, were evaluated after deep frying of fried products, namely aloo pakora, onion pakora, bread pakora, boondi, and meduvada. The FFA and PV after frying were 0.12 ± 0.01 and 1.16 ± 0.07, 0.13 ± 0.02 and 1.3 ± 0.01, 0.66 ± 0.01 and 2.63 ± 0.00, 0.13 ± 0.01 and 1.65 ± 0.05, 0.22 ± 0.01% and 0.92 ± 0.00 meq/kg for fried medium after frying of aloo pakora, onion pakora, bread pakora, boondi, and meduvada fried in palm olein respectively. A similar trend was also observed for AV, TV, CD, and CT, where sunflower oil showed higher deterioration upon frying than palm olein. The changes in fatty acids profile showed significant change in sunflower oil, evidenced by increased saturated fatty acids and decreased unsaturated fatty acids. The colour also increased significantly for both oil after frying, depicting the buildup of oxidative by-products in the frying medium. The prospect of palm olein for frying various Indian snacks is prominent owing to its thermal resistance and techno-economic benefits over sunflower oil
Study on oxidative stability of deep fat fried food in Canola oil blended with medium chain triglyceride.
No full text95-98In the present study potatoslices are deep fried in Canola oil blended with medium chain triglycerides. The oxidative
stability of deep-fried Potato slices is evaluated during their storage in dark. The potato slices were deep fried for 5 min in
hot oil blend of Canola Oil and MCT at the ratio of 90:10, 70:30, 50:50 and 40:60. The fried potato Slices were stored in a
glass container at room temperature in a dark place. The deep-fried potato slices were stored for 20 days in dark. The
oxidative stability was evaluated by estimation of peroxide value and formation of free fatty acid. The study revealed that
the peroxide value was less for following two blends i.e., 50:50 and 40:60 of Canola oil and MCT and the peroxide value
showed increased value for 90:10 and 70:30 blend of Canola oil: MCT. The left-over oil after frying was also evaluated for
its quality by checking percentage of free fatty acids formed in it. The quality of oil containing less MCT degraded quickly
as compared to blend containing high MCT
Coconut-Based Methyl Ester Sulfonate for Eco-Friendly Textile Scouring
No full textThe textile industry faces increasing pressure to adopt sustainable practices while maintaining product quality and economic viability. This study investigates the synthesis and application of methyl ester sulfonate (MES) derived from coconut fatty acid distillate (CFAD) as an eco-friendly alternative to conventional petroleum-based surfactants in textile scouring processes. CFAD, a renewable byproduct of coconut oil refining rich in medium-chain fatty acids, was converted to MES through acid-catalyzed esterification followed by sulfonation using sodium bisulfite. The synthesized MES exhibited excellent surface activity with surface tension reduction to 35.21 mN/m at 0.1% concentration, 64% emulsifying index, and superior biodegradability characteristics. Performance evaluation on cotton hosiery fabric, wool fibers, and polyester fabric demonstrated that MES achieved comparable or superior results to commercial surfactants. At 5.0% concentration, MES showed enhanced capillary rise (3.5 cm), improved whiteness index (68.48), and effective grease removal in wool scouring (15.8% weight loss) with reduced yellowness index (14.6). The bio-based MES surfactant offers significant environmental advantages including enhanced biodegradability, reduced aquatic toxicity, and utilization of renewable agricultural waste, making it a promising sustainable alternative for textile wet processing applications while maintaining industrial performance standards
Intensified synthesis of structured lipids from oleic acid rich moringa oil in the presence of supercritical CO2
No full textDrug resistant tuberculosis at a drug resistant tuberculosis centre, India- Analysis of outcome
No full text
