519 research outputs found
Characterization of apolipoprotein E genetic variations in Taiwanese: association with coronary heart disease and plasma lipid levels
Coronary Artery Disease Risk Predicted by Plasma Concentrations of High- Density Lipoprotein Cholesterol, Apolipoprotein AI, Apolipoprotein B, and Lipoprotein (a) in a General Chinese Population
The Pharmaceutical Research of Wu-Chia-Pi
五加皮藥材,其來源依藥學文獻均指為五加科(Araliaceae)五加屬A(Acanthopanax)若干種植物乾燥之根皮。我國本草將五加列於神農本草經草木部下品,自唐新修本草移附木部上品後,歷代諸家本草如開寶、嘉祐、圖經、証類、精要、圖考及長編等皆言五加皮,自古用於怯風濕,壯筋骨,活血,去瘀。治風寒濕痺,筋骨攣急,腰痛,陽痿,腳弱,小兒行遲,水腫,腳氣,瘡疽腫毒,跌打損傷諸症
五加皮藥材之來源植物甚多且復雜,一般文獻皆以細柱五加Acanthopanax listylu W.W. SMITH、無梗五加A. sessiliflorus (RUPR. et MAXIM.) SEEM、刺五加A. senticous (RUPR. et MAXIM.) HARMS、糙葉五加A. henryi (OLIV.) HARMS、輪葉五加A. verticillatus HOO為其代表,且為浸製五加皮酒之原料,時常飲之有強壯之功,為吾人酒宴乃至日常保健之飲料,關係國民健康至鉅。近年來報載五加皮酒有毒之說,甚受全國人士之重視與關懷。據那琦初步研究結果,南五加皮之原植物為五加屬植物無毒,北五加皮之原植物為杠柳有毒,隨後甘偉松等嘗著五加皮之藥用植物學考察。關於台灣地區所產本屬植物之本草學、生藥學之研究尚未見正式報告,著者因而進行本研究。
著者就採得之標本與市場品,進行五加之本草考察,以闡明其藥名、形態、種類、產地、性味、功能、修治、方用、禁忌、釀酒等歷史淵源,更而進行五加屬藥用植物等藥學之探討,以闡明其分類關係,五加藥材部分學者分隸於Acanthopanax MIQ.,Elentherococcus MAXIM.,Evodiopanax NAKAI,今統歸隸於五加屬植物,我國產30餘種植物予以索引敘述,並分辨刺五加(A. senticous HARMS)與杠柳(Periploca sepium BUNGE)比較解剖組織研究,以求証其真偽,有助於藥材之成分、藥理毒性及臨床應用等植物資源之開發。
Wu-Chia-Pi as a medical material, according to medical literature, can be derived from and referred to the dried root bark of those various plants of Acanthopanax species of Araliaceae, Family. The Chinese Pent¡¦ao lists Wu-Chia-Pi in Shen-Nung Pents’ao-Ching as Hsia-Ping under the category of Wood. Since the T’ang Dynasty Hsin-Hsiou-Pents¡¦ao moved it as Sang-Ping under the category of Wood, many schools of Pents¡¦ao in the succeeding dynasties, such as Kai-Pao, Chia-You, Tu-Ching, Cheng-Lay and Chang-Pian have all made mention of Wu-Chia-Pi, which has since ancient times been used to get rid of rheumatism, enhance the sinews and bones, activate blood circulation, remove blood clots, treat wind colds waist pain, impotence, and such symptoms as broken bones and injuries.
The plant sources of the medical material of Wu-Chia-Pi are quite numerous and complicated. The regular Wu-Chia-Pi can be represented by Acanthopanax gracilistylus W.W. SMITH, A. sessiliflorus SEEM, A. senticous HARMS, A. henryi HARMS and A. verticilatus Hoo, which can also serve as the raw materials for brewing Wu-Chia-Pi wine, which can function to strengthen the body if it is often taken and can also serve as healthful drink in banquets or in our daily lives; therefore, it has much to do with the health of the people. In recent years, there have been some newspaper report about the theories that Wu-Chia-Pi wine has poison in it, making it of great importance and concern by the Chinese people. As a result, several years ago the Legislative Yuan through the Monopoly Bureau prohibited the making and marketing of this wine. According to the study of Dr. Na-Chi, the plant of Nan-Wu-Chia-Pi is the poisonless Acanthopanax genus, whereas the original plant of the Pe-Wu-Chia-Pi is the poisonous Periploca sepium. Later professor, Wei-Song-Kang and others tried to investigate the medi-cal material of Wu-Chia-Pi. As for the locally grown plants of this genus in Taiwan areas, there is still no formal report about the science of Pents’ao and the science of raw medical for such plants, promptimg this author to conduct this research.
Using the collected samples and those products sold on the market, the author conducted the investigation of Wu-Chia Pents’ao in order to elucidate the medical names, patterns, varieties, places of origin, characteristic flavors, functions, and such wine brewing as the historical derivation. Furthermore, explorations is msde of the medical science of the plant genus of Wu-Chia in order to elucidate its categorical relationship. Scholars have categorized the part of Wu-Chia medical material into Acanthopanax MIQ, Eleutherococcus MAXIM, Evodiopanax NAKAT Now, it is categorized under the plant genus of Wu-Chia, in which there are some 30 kinds of plants grown in our country, which are placed in index for description. In addition to this, distinction is made between A. senticous HARMS and Periploca sepium BGE in order to compare their analytical compostion, to substantiate the true and the false ones, which will be helpful to the understanding of the ingredients of the medical material, the medicinal toxicity, and the resource development of those plants in clinical applications
[[alternative]]The effect of different intensities of active recovery on muscle function and running economy after exercise-induced muscle damage
[[abstract]]The effect of the different intensities of active recovery on muscle function and running economy after exercise-induced muscle damage
June 2005 Student:Chia-Ching Wu
Advisor:Sandy Shen-Yu Hsieh
ABSTRACT
Background:Should athlete continue to exercise when muscles are sored after strenuous exercise? Current literatures do not provide clear answers to this question. Post studies discussed the effect of exercise on muscle function after exercise-induced muscle damage. However, muscle function is not the only concern for endurance runners. Running economy should also be considered. Purpose:To determine the effect of a 6-day different intensities active recovery (50%、60%、70% VO2max) on muscle function and running economy after exercise-induced muscle damage. Methods:Forty Physical Education students (32 males & 8 females) took the VO2max and running economy test first. Then they were randomly assigned into 4 groups: E50(50% VO2max;n=10;♂=8、♀=2), E60(60% VO2max;n=10;♂=8、♀=2), E70(70% VO2max;n=10;♂=8、♀=2) and CON(control;n=10;♂=8、♀=2). A 30-min downhill running (-15%) at 70% VO2max was used to cause muscle damage. A 30-min active recovery running exercise was performed everyday for the following 6 days. Maximal isometric voluntary contraction strength (MVC) and muscle soreness were measured before, immediately after and 1, 2, 3, 4, 5, 6, 7 days after downhill running. Creatine kinase (CK) and lactate dehydrogenase (LDH) activities were also tested before, immediately after and 1, 3, 5, 7 days after downhill running. Running economy was determined 2, 5, 7 days after downhill running. Results:On the days 4 –7, both the CON’s and E50’s MVC were significantly higher than the E70 (p<.05). On the seventh day of the running economy test after downhill running, E50 was significantly different as compared to CON and E70(p<.05). No significant differences among groups in CK activity, LDH activity and muscle soreness (p>.05) were observed. Conclusions:1. Rest or moderate intensity active recovery (about 50% VO2max) is better for MVC recovery. Higher intensity of active recovery, will delay the normal course of MVC recovery. 2. Higher intensity of active recovery or rest was harmful to running economy. 3. When consider running economy and MVC together, moderate intensity of active recovery (about 50% VO2max) was better than rest or high intensity active recovery.
Key words:active recovery, muscle damage, running economy.
Characterization of Apolipoprotein E Genetic Variations in Taiwanese: Association with Coronary Heart Disease and Plasma Lipid Levels
Apolipoprotein E (apoE, protein; APOE, gene) is important in lipoprotein metabolism. Three isoforms, apoE2 (Cys112 Cys 158), apoE3 (Cys112 Arg158), and apoE4 (Arg112 Arg158), are present in the general population. This report investigates the frequency distribution of apoE isoforms and the association of APOE genotypes with plasma lipid profile and coronary heart disease (CHD) in a population of Taiwan. ApoE isoforms were determined genetically by polymerase chain reaction and HhaI restriction enzyme digestion in control and coronary heart disease (CHD) patients. Plasma lipid and lipoprotein concentrations were also determined. The control group exhibited frequencies of 84.6% APOE3, 7.9% APOE4, 7.5 % APOE2, 70.6% APOE3E3, 14.4% APOE3E4, 13.6% APOE2E3, and 1. 4% APOE2E4. Comparable frequencies were observed in the CHD group. In both APOE2 carrier and APOE 3E3 groups, the CHD patients expressed abnormal lipid profiles while the control group expressed normal lipid profiles. The APOE4 carriers, however , expressed abnormal lipid profiles in both normal control and CHD groups. Extremely high apoE levels in the hypertriglyceridemic group (TG > 400 mg /dL) seemed to be undesirable and were often observed in CHD patients
Use of Herbal Dietary Supplement Si-Wu-Tang and Health-Related Quality of Life in Postpartum Women: A Population-Based Correlational Study
Objective. The aim of the study was to explore the association between women's use of herbal dietary supplement Si-Wu-Tang during the postpartum period and their health-related quality of life. Methods. This is a population-based correlational study. We used multistage, stratified, systematic sampling to recruit 24,200 pairs of postpartum women and newborns from the Taiwan National Birth Registry in 2005. A structured questionnaire was successfully administered to 87.8% of the sampled population. Trained interviewers performed home interviews 6 months after the women's deliveries between June 2005 and July 2006. The Medical Outcomes Study 36-item Short-Form (SF-36) was used to measure the quality of life of the women along with the frequency of Si-Wu-Tang use. Results. Si-Wu-Tang use after delivery improved women's score for bodily pain and also improved their score for mental health when used more than 10 times. In addition, there were increases in general health and vitality scores in the group who continuously used Si-Wu-Tang more than 10 times after using Sheng-Hua-Tang. Conclusion. Use of Si-Wu-Tang after delivery may be associated with women's health-related quality of life especially for those who previously used Sheng-Hua-Tang. These results are exploratory and need to be replicated
Use of Herbal Dietary Supplement Si-Wu-Tang and Health-Related Quality of Life in Postpartum Women: A Population-Based Correlational Study
[[abstract]]Objective. The aim of the study was to explore the association between women’s use of herbal dietary supplement Si-Wu-Tang during the postpartum period and their health-related quality of life. Methods. This is a population-based correlational study. We used multistage, stratified, systematic sampling to recruit 24,200 pairs of postpartum women and newborns from the Taiwan National Birth Registry in 2005. A structured questionnaire was successfully administered to 87.8% of the sampled population. Trained interviewers performed home interviews 6 months after the women’s deliveries between June 2005 and July 2006. The Medical Outcomes Study 36-item Short-Form (SF-36) was used to measure the quality of life of the women along with the frequency of Si-Wu-Tang use. Results. Si-Wu-Tang use after delivery improved women’s score for bodily pain and also improved their score for mental health when used more than 10 times. In addition, there were increases in general health and vitality scores in the group who continuously used Si-Wu-Tang more than 10 times after using Sheng-Hua-Tang. Conclusion. Use of Si-Wu-Tang after delivery may be associated with women’s health-related quality of life especially for those who previously used Sheng-Hua-Tang. These results are exploratory and need to be replicated
Ellipsoid fitting up to constant via empirical covariance estimation
The ellipsoid fitting conjecture of Saunderson, Chandrasekaran, Parrilo and
Willsky considers the maximum number random Gaussian points in
, such that with high probability, there exists an
origin-symmetric ellipsoid passing through all the points. They conjectured a
threshold of , while until recently, known lower
bounds on the maximum possible were of the form . We
give a simple proof based on concentration of sample covariance matrices, that
with probability , it is possible to fit an ellipsoid through
random Gaussian points. Similar results were also obtained in two
recent independent works by Hsieh, Kothari, Potechin and Xu [arXiv, July 2023]
and by Bandeira, Maillard, Mendelson, and Paquette [arXiv, July 2023].Comment: 11 page
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