6,072 research outputs found
Buprenorphine alters ethanol self-administration in rats: Dose-response and time-dependent effects.
Performances of the HL (Hyperloop) transport system
This paper deals with an analysis of performances of the HL (Hyperloop) transport system considered as an advanced transport alternative to the existing APT (Air Passenger Transport) and HSR (High Speed Rail) systems. The considered performances are operational, financial, social and environmental. The operational performance include capacity and quality of service provided to the system’s users-passengers with attributes such as door-to-door travel time consisting of the access and egress time, schedule delay, in-vehicle time, and interchange time. The economic performances embrace the costs and revenues of operating the system. The costs include that for infrastructure, vehicles, traffic management facilities and equipment, and employees. The revenues embrace earnings from pricing users/passengers. The environmental performances include energy consumption and related emissions of GHGs (Green House Gases), and land use. The social performances are considered to be noise and safety. The analytical models of indicators of these performances are developed and applied to the scenario of operating the HL system on the short- to medium-haul travel distances/routes. These are then compared to the corresponding performances of the HSR and APT. This comparison has shown that the HL system may possess some advantages but also disadvantages regarding particular performances.Transport and PlanningOLD Urban and Regional Developmen
HL-LHC Accelerator
The tentative schedule, key ingredients, as well as progress of pertinent R&D and component prototypes for the LHC luminosity upgrade, "HL-LHC," are reviewed. Also alternative scenarios based on performance-improving consolidations (PICs) instead of a full upgrade are discussed. Tentative time schedules and expected luminosity evolutions for the different scenarios are sketched. The important role of HL-LHC development as a step towards a future HE-LHC or VHE-LHC is finally highlighted. Presented at "Higgs & Beyond" Conference Tohoku University, Sendai 7 June 2013
Analysis and modelling of performances of the HL (Hyperloop) transport system
Introduction: Hyperloop (HL) is presented as an efficient alternative of HSR (High Speed Rail) and APT (Air Passenger Transport) systems for long-distance passenger transport. This paper explores the performances of HL and compares these performances to HSR and APT. Methods: The following performances of the HL system are analytically modeled and compared to HSR and APT: (i) operational performance; (ii) financial performance; (iii) social/environmental performance. Results: The main operational result is that the capacity of HL is low which implies a low utilization of the infrastructure. Because the infrastructure costs dominate the total costs, the costs per passenger km are high compared to those for HSR and APT. The HL performs very well regarding the social/environmental aspects because of low energy use, no GHG emissions and hardly any noise. The safety performance needs further consideration. Conclusions: The HL system is promising for relieving the environmental pressure of long-distance travelling, but has disadvantages regarding the operational and financial performances.Transport and PlanningOLD Urban and Regional Developmen
Second HL-LHC Cold Powering System validated
The second Cold Powering System for the HL-LHC was assembled and qualified at CERN in June 2025. Tests and measurements in SM18 demonstrated stable and reproducible performance, and confirmed the electrical robustness of the design. 8 of these systems will be in the HL-LHC in total (2 each side of both ATLAS and CMS interaction points), and each features a cryogenic distribution box called DFH which will be in the new HiLumi galleries and a cryogenic distribution box in the LHC tunnel, connected via a Superconducting Link
Differential responding for brain stimulation reward and sucrose in high-alcohol-drinking (HAD) and low-alcohol-drinking (LAD) rats.
Effects of the benzodiazepine inverse agonist RO19-4603 on the maintenance of tolerance to a single dose of ethanol.
Wave 46, June 2013
Ipsos Global @dvisor wave 46 was conducted on June 4 and June 18, 2013. It included the following question sections: A: Demographic Profile, B: Consumer Confidence, R: Small Business/Executive Decision Makers Demo, HJ: Socialogue, CU: Immigration, HL: Questions on MERS (Middle Eastern Respiratory Syndrome)
CIRRUS-HL: Overview of LIM contributions
From June to July 2021, the Leipzig Institute for Meteorology (LIM)
participated in the Cirrus in High Latitudes (CIRRUS-HL) campaign. Utilizing the
German High Altitude Long Range Research Aircraft (HALO), 24 research flights were
conducted out of Oberpfaffenhofen, Germany. The initial goal of the campaign was
to sample high-latitude cirrus clouds with a combination of in-situ and remote sensing
instrumentation. However, due to the global coronavirus pandemic, the flights had to
be carried out from southern Germany instead of northern Sweden. Thus, the flight
time in Arctic latitudes was limited. Therefore, more objectives concerning midlatitude
cirrus were included in the campaign goals. LIM contributed to CIRRUS-HL with
measurements by the Broadband AirCrAft RaDiometer Instrumentation (BACARDI)
and the Spectral Modular Airborne Radiation measurement sysTem (SMART). While
BACARDI measured broadband solar and terrestrial upward and downward irradiance,
SMART measured spectrally resolved solar upward radiance as well as upward and
downward irradiance.Von Juni bis Juli 2021 nahmen einige Mitarbeitende des LIM
an der CIRRUS-HL Kampagne teil. Mit dem deutschen Forschungsflugzeug HALO
(High Altitude Long Range Research Aircraft) wurden 24 Forschungsflüge von Oberpfaffenhofen,
Deutschland, aus durchgeführt. Ursprüngliches Ziel der Kampagne war es,
Zirruswolken in hohen Breitengraden mit einer Kombination aus In-situ- und Fernerkundungsinstrumenten
zu untersuchen. Aufgrund der weltweiten Corona-Pandemie mussten
die Flüge jedoch von Süddeutschland statt von Nordschweden aus durchgeführt werden.
Daher wurden weitere Ziele in Bezug auf Zirruswolken in mittleren Breiten in die Ziele
der Kampagne aufgenommen. Das LIM-Team betrieb die breitbandigen und spektralen
Strahlungssensoren BACARDI (Broadband AirCrAft RaDiometer Instrumentation) und
SMART (Spectral Modular Airborne Radiation measurement sysTem), wobeiBACARDI
die breitbandige solare und terrestrische Auf- und Abwärtsstrahlung und SMART die
spektral aufgelöste solareAuf- undAbwärtsstrahlung sowie dieAufwärtsstrahlungsdichte
maß
Studies on the HL--A antigens Distributions among Normal Korean Population and Gastric Cancer Patients
Even though the HL-A antigens as the major
histocompatibility antigens have been contributing
an important role in the immunological aspect of the
clinical transplantation. and recently considerable
attentions are focusing on the possible association
of various disease or malignant disease with the
certain HL-A specifities, any datas for the distribution
of the HL-A antigens in Korean population and
the HL-A serotyping for the kidney transplant is
not available at present time.
This present report is a studies on the HL-A
antigens distribution among 155 normal Korean
population and 76 gastric cancer patients with the
method of Boyum's lymphocyte isolation technic
with Ficoll and Isopaque mixture and the method
of Terasaki's microlymphocytotoxicity test with 29
NIH standard antisera for 16 HL-A specificities at
Seoul National University Hospital.
The results are as following;
1. The HL-A antigens are rather evenly distributed
throughout the first and second series in both normal
Koreans and gastric cancer patient which is a good
evidence of diversity in the polymorphism of HL-A
antigens.
2. The most frequent HL-A antigens are HL-A 2,13.12 and 10 in normal control group. and HL-A
10.5.2 and 13 in gastric cancer patient. HL-A 9 is
rather infrequent compared to other Oriental populations,
and HL-A 1 which has heen recognized to be
absent from Orientals occurs 17.4%.
3. It is interesting findings that in gastric cancer
group HL~A 10 from first sublocus and 5 from second
sublocus are markedly increased than normal control
group and HL-A 11 from first sublocus and 12 from
second sublocus are markedly decreased than normal
control group. The author strongly feels that
. additional study to confirm the above findings
should be done.
4. There is a relatively large proportion of blank
alleles: 24% (first series) and 15% (second series) in
normal control group, and 22% (first series) and
15% (second series) in gastric cancer group, which
seems to be related to the limited number of antisera
and the limited number of serum panels used in this
study, and related to the probable existence of
unknown specifities in OUf native Korean population
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