2,861 research outputs found
FIGURE 4 in First Inventory of Sea Anemones (Cnidaria: Actiniaria) of the Mexican Caribbean
No full textFIGURE 4.—Bunodosoma granuliferum. (A) Live specimen, lateral view. (B) Oral view. (C) Pedal disc view. (D) Lateral view. (E) Cross section through distal column. (F) Longitudinal section through column margin. (G–Q) Cnidae.—tentacles: (G) basitrich, (H) spirocyst; actinopharynx: (I) basitrich, (J) basitrich, (K) microbasic p-mastigophore; column: (L) basitrich, (M) basitrich; acrorhagi: (N) basitrich, (O) holotrich; filament: (P) basitrich, (Q) microbasic p-mastigophore. Abbreviations.—acr: acrorhagi, c: column, fo: fossa, msp: marginal sphincter, od: oral disc, pb: parietobasilar muscles, pd: pedal disc, rm: retractor muscles, s: siphonoglyph, t: tentacle, ve: vesicle. Scale bars.—A–D: 10 mm; E–F: 200 µm; G–Q: 25 µm.Published as part of Gonzalez-Muñoz, Ricardo, Simões, Nuno, Sanchez-Rodriguez, Judith, Rodriguez, Estefania & Segura-Puertas, Lourdes, 2012, First Inventory of Sea Anemones (Cnidaria: Actiniaria) of the Mexican Caribbean, pp. 1-38 in Zootaxa 3556 on page 17, DOI: 10.5281/zenodo.20398
A feminist guide to hacking this tech gatebox "Azuma Hikari"
No full textDouglas College student research essay submitted as partial requirement for GSWS 2101: Gender Today (Fall 2021) course. Faculty sponsor to submit this essay to DOOR: Dr. Jill Fellows.
The use of virtual assistants is increasing every day, as a technological tool that is marketed as a necessity to assist in making our modern lives more efficient. These tools are designed to help us with daily tasks such as searching for information, reading emails, writing messages, making calls and scheduling meetings with others. The most popular examples “Siri” or “Alexa” have been created with specific gendered characteristics and behavior as the author points out “virtual assistants are very obviously gendered. Siri and Alexa both have female names”, (Fellows, forthcoming 2022) designed with a personality of submissive and serviceable, as the author mentions “they portray a gender binary dominant-submissive relationship, positioning the user in the dominant position, and they play out subordination as feminine.” (Fellows, forthcoming 2022)Not peer reviewe
Eating to add years of life and life to these years: what should be in the menu? [editorial].
No full textThe author Elena Gonzalez Rodriguez is not properly referenced in PubMed. The reference shows as "Rodriguez E.G.", but should be "Gonzalez Rodriguez E.". - Comment on: Diet quality as a predictor of cardiometabolic disease-free life expectancy: the Whitehall II cohort study. Auteurs: Lagström H, Stenholm S, Akbaraly T, Pentti J, Vahtera J, Kivimäki M, Head J.
Am J Clin Nutr. 2020 Apr 1;111(4):787-794. doi: 10.1093/ajcn/nqz329
Regulation of human pancreas hormone secretion by autonomic innervation
No full textDiabetes mellitus is a silent killer doing away with one person every 10 seconds. We speak of diabetes when the organism cannot control the right level of glucose in the blood. The hormones insulin and glucagon secreted by the islets of Langerhans are the major players maintaining glucose homeostasis. In the living organism, the function of the islets is orchestrated by their interaction with other organs through the vasculature and with the nervous system. Most of our current knowledge of islet biology has been obtained by using mouse models, but caution is needed, as mice are not simply small humans. Indeed, recent studies have revealed that the cell composition and architecture of the human islet are different from that of mouse islets. Thus, other important features such as nervous regulation of islet function may also be different.The work in this thesis aimed to identify the role of innervation for islet function. Our hypothesis is that autonomic and paracrine signals are involved in islet function and that the relative role of these components varies among species. To identify the sympathetic and parasympathetic components of innervation as well as their cellular targets we used immunohistochemical staining of human and mouse pancreatic sections. In contrast to mouse, human islets are devoid of parasympathetic innervation. Instead, human alpha cells possess the machinery for exocytosis of acetylcholine, the major parasympathetic neurotransmitter. Our findings suggest that human islets depend less on neural cholinergic input than mouse islets. Alpha cells secrete acetylcholine as a paracrine signal priming the human beta cell to respond optimally to subsequent increases in glucose concentration. In addition, noradrenergic fibers contact few endocrine cells in the human islet and preferentially innervate smooth muscle cells of the islet vasculature. This suggests that sympathetic innervation regulates hormone secretion by controlling the blood flow rather than modulating endocrine cell function directly.By taking advantage of our recently developed noninvasive anterior chamber of the eye imaging platform we were able to study the role of innervation in the maintenance of glucose homeostasis in vivo. We studied the process of reinnervation and revascularization of intraocular islet grafts and showed that islets orchestrate the process of engraftment to restore their original microenvironment. Islet grafts from two different mouse strains and human xenografts showed innervation patterns similar to those in pancreatic sections in situ. Islet grafts displayed the characteristic fenestrae of the pancreatic vascular endothelium independently of the origin of the new vessels. In addition, the model allowed controlling the fraction of the graft vasculature that is contributed by the donor islet endothelial cells to the point that the original donor vasculature of the islet is restored. Recording graft function while manipulating the eye’s neural input through the pupillary light reflex revealed functional differences in parasympathetic innervation between the two mouse strains. The eye platform also allowed us to follow cell dynamics during immune responses, which will enable investigations aimed at clarifying the role of innervation in the pathogenesis of autoimmune diabetes.To study human islet biology in vivo we further adopted the eye model by transplanting human islets into the eye of diabetic immune compromised mice. Human xenografts reversed diabetes and tightly controlled plasma glucose concentrations. Moreover, our results provided the first real time monitoring of revascularization and blood flow inside human islets and graft function could be modulated by local drug administration. Our findings establish a “humanized” mouse model to investigate human islet biology in vivo that will allow addressing how nervous input affects endocrine function or blood flow in human islets. The physiological relevance of the anterior chamber of the eye model is further underscored by the therapeutic potential as a novel transplantation site to treat type 1 diabetic patients.List of scientific papersI. Rayner Rodriguez-Diaz, Midhat H. Abdulreda, Alexander L. Formoso, Itai Gans, Camilo Ricordi, Per-Olof Berggren, Alejandro Caicedo (2011). Autonomic axons in the human Endocrine pancreas show unique innervation patterns. Cell Metabolism. Jul 6;14(1):45-54. https://doi.org/10.1016/j.cmet.2011.05.008 II. Rayner Rodriguez-Diaz, Robin Dando, M. Caroline Jacques-Silva, Alberto Fachado, Judith Molina, Midhat H. Abdulreda, Camilo Ricordi, Stephen D. Roper, Per-Olof Berggren, Alejandro Caicedo (2011). Acetylcholine is released by human alpha cells as a paracrine signal to prime beta cell insulin secretion. Nat Med. Jul 19;17(7):888-92. https://doi.org/10.1038/nm.2371 III. Rayner Rodriguez-Diaz, Robin Dando, Y. Anthony Huang, Per-Olof Berggren, Stephen D. Roper, Alejandro Caicedo (2011). Real time detection of acetylcholine release from the human endocrine pancreas. [Submitted]IV. Rayner Rodriguez-Diaz, Stephan Speier, Damaris Molano, Alexander L. Formoso, Itai Gans, Midhat Abdulreda, Over Cabrera, Alberto Fachado, Camillo Ricordi, Ingo Leibiger, Antonello Pileggi, Per-Olof Berggren, and Alejandro Caicedo (2011). A simple noninvasive system for investigating the role of innervation in pancreatic islet function in vivo. [Submitted]V. Daniel Nyqvist, Stephan Speier, Rayner Rodriguez-Diaz, R. Damaris Molano, Sasa Lipovsek, Marjam Rupnik, Andrea Dicker, Erwin Ilegems, Elsie Zahr-Akrawi, Judith Molina, Maitee Lopez-Cabeza M, Susana Villate, Midhat H. Abdulreda, Camilo Ricordi, Alejandro Caicedo, Pileggi, Per-Olof Berggren (2011). Donor islet endothelial cells in pancreatic islet revascularization. Diabetes. 60(10):2571-7. https://doi.org/10.2337/db10-1711 VI. Midhat H. Abdulreda, M, Gaetano Faleo, R. Damaris Molano, Judith Molina, Y. Tan, Ron Echeverria, Elsie Zahr-Akrawi, Rayner Rodriguez-Diaz, P. Edlund, Ingo Leibiger, Alisson L. Bayer, Victor L. Perez, Camilo Ricordi, Alejandro Caicedo, Antonello Pileggi, Per-Olof Berggren (2011). High resolution, non-invasive longitudinal live imaging of immune responses. Proc Natl Acad Sci U S A. 108(31):12863-8. https://doi.org/10.1073/pnas.1105002108 VII. Victor L. Perez, Alejandro Caicedo, Dora M. Berman, E. Arrieta, Midhat H. Abdulreda, Rayner Rodriguez-Diaz, Antonello Pileggi, E. Hernandez, S. R. Dubovy, Jean-Marie Parel, Camilo Ricordi, Norma M. Kenyon, Per-Olof Berggren (2011). The anterior chamber of the eye as a clinical transplantation site for the treatment of diabetes. Diabetologia. 54(5):1121-6. https://doi.org/10.1007/s00125-011-2091-y </p
Analysis of the Hirsch index's operational properties
No full textThe h-index is a relatively recent bibliometric indicator for assessing the research output of scientists, based on the publications and the corresponding citations. Due to the original characteristics of easy calculation and immediate intuitive meaning, this indicator has become very popular in the scientific community. Also, it received some criticism essentially because of its ‘‘low" accuracy. The contribution of this paper is to provide a detailed analysis of the h-index, from the point of view of the indicator operational properties. This work can be helpful to better understand the peculiarities and limits of h and avoid its misuse. Finally, we suggest an additional indicator ðf Þ that complements h with the information related to the publication age, not compromising the original simplicity and immediacy of understandin
Assessment of lead tolerance on Glycine max (L.) Merr. at early growth stages
No full textLead (Pb) contamination of agricultural soils, and subsequently of crops, has been widely reported. Soybean (Glycine max (L.) Merr.) has been indicated as a plant that accumulates Pb, even in soils that do not exceed the maximum permissible levels. Considering the toxicity of this heavy metal, the aim of the present study was to assess different concentrations of Pb, from low to extremely high (0.25 mM, 1 mM, and 2.5 mM), in soybean seedlings and their tolerance by analyzing morpho-physiological parameters in hydroponic experiments. Soybean seedlings were exposed to control and Pb treatments during 8 days, coinciding with the early growth stages, and the following variables were analyzed: biomass, Pb content in roots, stems and leaves, photosynthetic efficiency, leaf area, biochemical response (antioxidant power, chlorophylls, malondialdehyde), and relative water content of leaves. Results showed that roots accumulated much more Pb than the other organs, with Pb accumulation in roots being saturated even at the lowest Pb concentration, which was reflected in root biomass. Moreover, absorption of culture solutions was lower in Pb treatments, which was also reflected in the lower leaf relative water content. Lead toxicity symptoms in leaves (chlorosis and dark spots, and a decrease of biomass and leaf area, chlorophyll content, and photosynthetic efficiency), and an increase of the oxidative defense system were associated only with the highest Pb concentration (2.5 mM). Our findings support the evidence of soybean as a species tolerant to Pb, showing the effects of toxicity at very high concentrations.Instituto de Fisiología y Recursos Genéticos VegetalesFil: Blanco, Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores; ArgentinaFil: Blanco, Andrés. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Pignata, María L. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores; ArgentinaFil: Pignata, María L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Lascano, Hernán Ramiro. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Cátedra de Fisiología Vegetal; ArgentinaFil: Lascano, Hernán Ramiro. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Unidad de Estudios Agropecuarios (UDEA); ArgentinaFil: Lascano, Hernán Ramiro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales. ArgentinaFil: Rodriguez, Judith H. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores. ArgentinaFil: Rodriguez, Judith H. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentin
Lead uptake and translocation pathways in soybean seedlings: the role of ion competition and transpiration rates
No full textGlycine max (L.) Merr. (soybean) crop plants have been found to have high lead (Pb) levels in aerial organs; however, knowledge about the processes involved in the incorporation, and subsequent translocation and accumulation of the metal in the plants is scarce. Considering the toxicity of this heavy metal, the aim of the present study was to evaluate Pb uptake and translocation, and their toxic effects on soybean seedlings via experiments of ionic competition with Ca2+ (2.5 mM, Ca:Pb 1:1) and alteration of the transpiration flow [0.25 mM Pb(NO3)2]. The following variables were analyzed: biomass, leaf area (morphological parameters), photosynthetic efficiency, biochemical response (considered physiological stress markers: antioxidant power, chlorophylls, carotenoids, starch, proteins, sugars, and malondialdehyde), and Pb content. Results showed that soybean seedlings can accumulate high Pb concentration in its organs; however, in general, no morpho-physiological Pb stress symptoms were observed, except for lipid peroxidation and antioxidant power. The treatment with Ca ions was not effective in reducing Pb entry into root over time when both Ca and Pb where present in the grow solution. Alteration of the transpiration rate in soybean showed that the air flow increased the consumption of solutions, regardless of the treatments.Instituto de Fisiología y Recursos Genéticos VegetalesFil: Blanco, Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores; ArgentinaFil: Blanco, Andrés. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Pignata, María L. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores; ArgentinaFil: Pignata, María L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Lascano, Hernán Ramiro. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Cátedra de Fisiología Vegetal; ArgentinaFil: Lascano, Hernán Ramiro. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Estudios Agropecuarios (UDEA); ArgentinaFil: Lascano, Hernán Ramiro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Fisiología y Recursos Genéticos Vegetales; ArgentinaFil: Salazar, María J. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores; ArgentinaFil: Salazar, María J. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Rodriguez, Judith H. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto Multidisciplinario de Biología Vegetal (IMBIV). Área Contaminación y Bioindicadores; ArgentinaFil: Rodriguez, Judith H. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentin
Biomonitoring of airborne fluoride and polycyclic aromatic hydrocarbons in industrial areas of Cordoba, Argentina, using standardized grass cultures of Lolium multiflorum
No full textA biomonitoring study was performed employing standardized grass cultures. Plants of Lolium multiflorum were exposed at 4 industrial sites over three?month periods in two seasons (dry and rainy) and the biomass produced was used for subsequent measurements of fluoride, polycyclic aromatic hydrocarbons (phenanthrene, anthracene, pyrene, benzo[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenzo[a,h]‐ anthracene and benzo[g,h,i]perylene), total chlorophyll, malondialdehyde, water, and sulfur content. The total content of polycyclic aromatic hydrocarbons (PAHs) revealed seasonal variations, with the highest values corresponding to the dry season, although this species showed a high retention capacity of PAHs during rainy season. In addition, sampling sites with high vehicular traffic and metal?mechanical industries were associated with the highest content of PAHs. Furthermore, physiological degradation associated with anthropogenic activities in the sampling sites was observed. Fluoride content in the biomonitor was associated with the production and use ofcement, which was higher in the dry season.Fil: Rodriguez, Judith Hebelen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Wannaz, Eduardo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Franzaring, Jurgen. Universidad de Hohenheim. Instituto de Paisaje y Ecología Vegetal. Especialidad En Ecología Vegetal y Ecotoxicologia; AlemaniaFil: Klumpp, Andreas. Universidad de Hohenheim. Instituto de Paisaje y Ecología Vegetal. Especialidad En Ecología Vegetal y Ecotoxicologia; AlemaniaFil: Fangmeier, Andreas. Universidad de Hohenheim. Instituto de Paisaje y Ecología Vegetal. Especialidad En Ecología Vegetal y Ecotoxicologia; AlemaniaFil: Pignata, Maria Luisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentin
Author Correction : Studying temperature’s impact on Brassica napus resistance to identify key regulatory mechanisms using comparative metabolomics (Scientific Reports, (2024), 14, 1, (19865), 10.1038/s41598-024-68345-3)
No full textCorrection to: Scientific Reportshttps://doi.org/10.1038/s41598-024-68345-3, published online 27 August 2024 The original version of this Article contained an error in the Author Contributions section. “H. Hamzehzarghani contributed in conceptualization, methodology, and visualization of the investigation, defining the general hypothesis, designing the experiments based on the hypothesis, supervising the research project throughout, analyzing and interpreting the results, administering the chemical and statistical analysis and writing the original draft of the main manuscript and revising, reviewing and/or editing of the text. Z. Amjadi performed the research throughout her Ph.D. project, contributed in analyzing the results, the chemical and statistical analysis, as well as revising, reviewing and editing of the text. V.M. Rodriguez helped us with resources and hyphenated instrumentation by providing UPLC-QTOF/MSm methodology, and formal analysis. Y. Huang helped with methodology and providing resources [two canola cultivars (Drakkar—susceptible without any resistance genes and Excel- resistant carrying the resistance gene Rlm7) and one Lm isolate EM24, which possesses three known effectors (AvrLm1, AvrLm6, and AvrLm7)]. F. Farahbakhsh helped with chemical and statistical analysis.” now reads: “H. Hamzehzarghani contributed in conceptualization, methodology, and visualization of the investigation, defining the general hypothesis, designing the experiments based on the hypothesis, supervising the research project throughout, analyzing and interpreting the results, administering the chemical and statistical analysis and writing the original draft of the main manuscript and revising, reviewing and/or editing of the text. Z. Amjadi performed the research throughout her Ph.D. project, contributed in analyzing the results, the chemical and statistical analysis, as well as revising, reviewing and editing of the text. V.M. Rodriguez helped us with resources and hyphenated instrumentation by providing UPLC-QTOF/MSm methodology, and formal analysis. Y. Huang helped with methodology and providing resources [two canola cultivars (Drakkar and Excel) and one LM isolate EM24], revising and editing the text. F. Farahbakhsh helped with chemical and statistical analysis.” The original Article has been corrected
Correction to: NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL (Leukemia, (2018), 32, 3, (633-644), 10.1038/leu.2017.294)
No full textThe original version of this Article contained an error in the spelling of the author Juan Carlos Rodriguez-Manzaneque, which was incorrectly given as J Carlos Rodríguez-Manzaneque. This has now been corrected in both the PDF and HTML versions of the Article
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