25,153 research outputs found
Dr. Lin Sun, CAU, March 2013
This video is a conversation with Dr. Lin Sun. Dr. Sun talks about an exhibit at the Woodruff Library titled "At The Boundary." Jordan Moore, AUC Woodruff Library, is the interviewer
The Tyrosine Phosphatase CD148 is Excluded from the Immunologic Synapse and Down-regulates Prolonged T Cell Signaling
?? Joseph Lin and Arthur Weis, 2011. Originally published in The Journal of Cell Biology. doi: 10.1083/jcb.200303040.CD148 is a receptor-like protein tyrosine phosphatase\ud
up-regulated on T cells after T cell receptor\ud
(TCR) stimulation. To examine the physiologic role\ud
of CD148 in TCR signaling, we used an inducible CD148-\ud
expressing Jurkat T cell clone. Expression of CD148 inhibits\ud
NFAT (nuclear factor of activated T cells) activation induced\ud
by soluble anti-TCR antibody, but not by antigen-presenting\ud
cells (APCs) loaded with staphylococcal enterotoxin superantigen\ud
(SAg) or immobilized anti-TCR antibody. Immunofluorescence\ud
microscopy revealed that the extracellular\ud
C\ud
domain of CD148 mediates its exclusion from the immunologic\ud
synapse, sequestering it from potential substrates.\ud
Targeting of the CD148 phosphatase domain to the immunologic\ud
synapse potently inhibited NFAT activation by all\ud
means of triggering through the TCR. These data lead us to\ud
propose a model where CD148 function is regulated in\ud
part by exclusion from substrates in the immunologic synapse.\ud
Upon T cell???APC disengagement, CD148 can then\ud
access and dephosphorylate substrates to down-regulate\ud
prolongation of signaling.This work was supported in part by research funds from the state of California
Rathalos treecko Lin & Zhao & Koh & Li 2022, comb. nov.
Rathalos treecko (Lin & Li, 2021) comb. nov. Anyphaena treecko Lin & Li, In: Lin et al., 2021: 101, figs 9A–C, 10A–B, 14I–J. Material examined. Holotype ♂ (IZCAS-Ar42404), China: Hainan, Changjiang County, Bawangling, Dongsizhan (19.0495°N, 109.1157°E), 23 April 2009, G. Tang leg. (examined). Paratypes. 2♀ (IZCAS-Ar42405–Ar42406), same data as holotype (examined). Diagnosis. See Lin et al. (2021). Description. See Lin et al. (2021). Distribution. China (Hainan). Comments. The cymbial apophysis, the triangular epigyne and the straight copulatory duct indicate that this species belongs to Rathalos Lin & Li, gen. nov. Thus, we transfer it from Anyphaena to Rathalos Lin & Li, gen. nov.Published as part of Lin, Yejie, Zhao, Huifeng, Koh, Joseph K H & Li, Shuqiang, 2022, Taxonomy notes on twenty-eight spider species (Arachnida: Araneae) from Asia, pp. 198-270 in Zoological Systematics 47 (3) on page 201, DOI: 10.11865/zs.2022303, http://zenodo.org/record/717585
The c-SMAC: Sorting It All Out (or in)
?? Lin, Joseph, Mark Miller, and Andrey Shaw. 2005. Originally published in The Journal of Cell Biology. doi: 10.1083/jcb.200503032.T cells integrate and transduce the key signals necessary\ud
to mount an appropriate immune response. To do this,\ud
they rely on both secreted factors as well as physical cell???\ud
cell contact. Much attention has focused on the organization\ud
of proteins at the contact area between a T cell and an\ud
antigen-presenting cell, known as the immunological\ud
synapse. It has been shown in vitro that proteins segregate\ud
into two distinct regions within this contact area, a central\ud
area referred to as the c-SMAC, where the T cell receptor\ud
and associated signaling molecules are enriched, and a\ud
peripheral region called the p-SMAC containing LFA-1\ud
and the scaffolding protein talin. Whether or not these\ud
structures form in vivo and how they function in T cell\ud
activation remain issues of great interest. Here, we review\ud
recently published work and propose several possible\ud
functions for the role of the c-SMAC in T cell activation
An Analysis of <i>Judge Lin</i>
Biography of Lin Wen Zhong Gong has another way to call, that is Judge Lin. The leading character is Lin Ze-Xu. This book is based on functionary experience of Lin Ze-Xu, with the captivating plots of court case, helping by highly skilled military attach\uc3\ua9s and chivalrous knights, and the history facts of Opium War. It makes Lin Ze-Xu\ue2s Confucian temperament and tragic mood more, also contrasts with author\ue2s sorrow and furiousness for the politics at the time. History, court case, martial arts\ue2\ua6\ue2\ua6etc. are essence of this book and it broadens the way of this writing style.
The topic of the thesis is \ue2An Analysis of Judge Lin\ue2. The following thesis will be divided into six different chapters. The introduction is Chapter one of the thesis, which is including researching motive and purpose, literature review of predecessors, researching version by existing information, raising questions, choosing research methods and arranging chapters. In chapter Two, I discuss the study of characters of Lin Ze-Xu, also makes a deep analysis of author\u27s purpose of writing him. In chapter Three, I analyze supporting actors and actress. Meanwhile, I illustrate author\u27s purpose of writing supporting actress because the author had different manner to describe supporting actress. Moving to the Chapter Four, I mainly focus on the plots of Judge Lin, and organize cases of Lin Ze-Xu and his subordinates to understand features of cases. In Chapter Five, I represent the causes of Opium War. China and England had difference of opinions of opium. Therefore, it is easier to comprehend what the author\u27s purpose is. In the last chapter I summarize the main points of the preceding chapters and confirm particularity of Judge Lin
Primer concierto de Joseph Matza en el Conservatorio Departamental de Ibagué
- Melodía (Gluck)
- Siciliana y Rigaudon (Francoeur)
- Minueto (Beethoven)
- Rondó (Mozart)
- Concierto en Mi (F. Mendelssohn Bartholdy)
- La fille aux cheveux de lin (Debussy)
- Zapateado (Sarasate)
- Canción de cuna (Schubert)
- Danza de las brujas (N.Pertenece al archivo de Joseph Matza DusekMedellín, Biblioteca Luis Echavarría Villegas, Sala de Patrimonio Documental, Colección Programas de manoIbagué. Teatro Departamenta
Maya Lin Statement on the Civil Rights Memorial, July 1988
A statement by artist Maya Lin regarding her design of the Civil Rights Memorial in Montgomery, Alabama. 2 pages.The Atlanta University Center Robert W. Woodruff Library acknowledges the generous support of the Joseph & Evelyn Lowery Institute for Justice and Human Rights, the Joseph Echols Lowery Irrevocable Trust, and other donors in supporting the processing and digitization of Morehouse College's Joseph Echols and Evelyn Gibson Lowery Collection
Figure 23. Paratus nanling Lin & Li in Taxonomy notes on twenty-eight spider species (Arachnida: Araneae) from Asia
Figure 23. Paratus nanling Lin & Li, sp. nov., live specimens. A. Holotype male; B. Paratype female. Photos: Qianle Lu.Published as part of Lin, Yejie, Zhao, Huifeng, Koh, Joseph K H & Li, Shuqiang, 2022, Taxonomy notes on twenty-eight spider species (Arachnida: Araneae) from Asia, pp. 198-270 in Zoological Systematics 47 (3) on page 226, DOI: 10.11865/zs.2022303, http://zenodo.org/record/717585
Figure 55. Dolichognatha yue Lin & Li in Taxonomy notes on twenty-eight spider species (Arachnida: Araneae) from Asia
Figure 55. Dolichognatha yue Lin & Li, sp. nov., live specimens. A. Holotype male; B. Paratype female. Photos: Qianle Lu.Published as part of Lin, Yejie, Zhao, Huifeng, Koh, Joseph K H & Li, Shuqiang, 2022, Taxonomy notes on twenty-eight spider species (Arachnida: Araneae) from Asia, pp. 198-270 in Zoological Systematics 47 (3) on page 260, DOI: 10.11865/zs.2022303, http://zenodo.org/record/717585
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