365 research outputs found

    Grid-based semantic integration of heterogeneous data resources: Implementation on a HealthGrid

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    This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.The semantic integration of geographically distributed and heterogeneous data resources still remains a key challenge in Grid infrastructures. Today's mainstream Grid technologies hold the promise to meet this challenge in a systematic manner, making data applications more scalable and manageable. The thesis conducts a thorough investigation of the problem, the state of the art, and the related technologies, and proposes an Architecture for Semantic Integration of Data Sources (ASIDS) addressing the semantic heterogeneity issue. It defines a simple mechanism for the interoperability of heterogeneous data sources in order to extract or discover information regardless of their different semantics. The constituent technologies of this architecture include Globus Toolkit (GT4) and OGSA-DAI (Open Grid Service Architecture Data Integration and Access) alongside other web services technologies such as XML (Extensive Markup Language). To show this, the ASIDS architecture was implemented and tested in a realistic setting by building an exemplar application prototype on a HealthGrid (pilot implementation). The study followed an empirical research methodology and was informed by extensive literature surveys and a critical analysis of the relevant technologies and their synergies. The two literature reviews, together with the analysis of the technology background, have provided a good overview of the current Grid and HealthGrid landscape, produced some valuable taxonomies, explored new paths by integrating technologies, and more importantly illuminated the problem and guided the research process towards a promising solution. Yet the primary contribution of this research is an approach that uses contemporary Grid technologies for integrating heterogeneous data resources that have semantically different. data fields (attributes). It has been practically demonstrated (using a prototype HealthGrid) that discovery in semantically integrated distributed data sources can be feasible by using mainstream Grid technologies, which have been shown to have some Significant advantages over non-Grid based approaches

    Interview with Robert Johnson (Class of 1971) by Aisha Rickford

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    Robert Johnson, Class of 1971, talks about his first visit to Bowdoin in 1967 with a friend, and being involved with BUCRO, the Bowdoin Undergraduate Civil Rights Organization. There, he met Virgil Logan, president of BUCRO and an instrumental face on campus and in the Bowdoin African American Society. Johnson details how Afam came about after the assassination of Martin Luther King Jr out of a desire to form community. Johnson then became the first President of the AfroAm at Bowdoin College. Johnson talks about how critical AfAm was for him and fellow black students isolated from their respective communities and drove black students to organize, and change racist systems. He shares stories of activism and resistance carried out on campus, specifically one where the black students on campus went silent and marched across campus to protest the lack of action on part of the Bowdoin administration as far as ensuring racial diversity in future classes. He also talks about racial incidents at Bowdoin and how Bowdoin shaped him in the years during and after graduation

    Supplemental material - Patterns of Lipid Lowering Therapy Use Among Older Adults in a Managed Care Advantage Plan in the United States

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    Supplemental material for Patterns of Lipid Lowering Therapy Use Among Older Adults in a Managed Care Advantage Plan in the United States by Aisha Vadhariya, Manvi Sharma, Susan M. Abughosh, Kim K. Birtcher, Hua Chen, Anjana Mohan, and Michael L. Johnson in Journal of Pharmacy Practice</p

    New Librarian, New Challenge

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    Interview portion of Lost in the Stacks, episode 511. Features interview with Aisha Johnson, the Associate Dean for Academic Affairs & Outreach at the Georgia Tech Library. Dr Johnson discusses entering library administration, facing challenges with organizational diversity, and her career in libraries and archives.Interview portion of Lost in the Stacks, episode 511. Features interview with Aisha Johnson, the Associate Dean for Academic Affairs & Outreach at the Georgia Tech Library. Dr Johnson discusses entering library administration, facing challenges with organizational diversity, and her career in libraries and archives

    Does Reassessment of Risk Improve Predictions? A Framework and Examination of the SAVRY and YLS/CMI

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    Author NoteJodi L. Viljoen, Andrew L. Gray, Catherine Shaffer, Aisha Bhanwer, Donna Tafreshi, and Kevin S. Douglas, Department of Psychology, Simon Fraser University.This research was supported by a grant from the Social Sciences and Humanities Research Council of Canada, and a Career Investigator Award for the first author from the Michael Smith Foundation for Health Research.Correspondence concerning this article should be address to Jodi Viljoen, Department of Psychology, Simon Fraser University, Burnaby, BC V5A 1S6. Contact: [email protected]

    Impact Magazine, Winter 2018

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    Aisha Hinds; Torrei Hart; Ericka Pittman; Vanessa Simmons; Shanice Wilson; Olori Swank; Arnita Johnson-Hall; Ebony Porter-Ike; Khat Brim; Ashley Williams; Kiki Ayer

    THE CULTURAL REPRESENTATION OF AMERICAN AND PAKISTANI AS SEEN IN AISHA SAEED’S WRITTEN IN THE STARS

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    Representation of culture is portrayed in literary works. The representation of culture brings the reproduction of the said culture into public eyes. When the representation of a culture is wrongly done, the country whose culture is being presented takes its burden. This problem is depicted in Aisha Saeed’s Written in the Stars. Regarding the issue, this research is intended to analyze the cultural representation of two cultures presented by the author in the story using Stuart Halls representation theory. Furthermore, this is qualitative research in which the researcher comprehends social problems based on detailed information in its natural setting on the novel. Based on the analysis, the representation of two cultures, which are Pakistan and America, varies from each other. The cultural representation of Pakistan emphasizes the condition of a third-world country with issues of how women are unfairly treated. In contrast, the cultural representation of America explains the country, aside from their sexes, treats individuals fairly

    Coping strategies for social well-being and social development intervention: young women and unintended pregnancy in Mozambique

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    Using the concept of coping strategies, this thesis is essentially concerned with the wayyoung women in Mozambique achieve social well-being during the life event of unintendedpregnancy. Unintended pregnancy in Mozambique places significant strain on informal andformal relationships, educational access, economic stability and the maintenance of goodhealth. It also has significant implications for young women’s roles, responsibilities and statuswithin families and communities (CEDAW 2005). Twenty one qualitative semi-structuredindividual interviews were completed with young women (16-19 years old) who have recentlyhad an unintended pregnancy, as well as eight focus groups using a vignette with youngwomen (16–21 years old) from youth associations and fourteen individual interviews with keyinformants (those working in the area of sexual and reproductive health with youth andadolescents). From these three forms of rich data, the relationships young women have withothers, the negotiations they engage in and the coping strategies they employ are illuminated.This research contributes to an increased understanding of unintended pregnancy and theways young women respond and ‘cope’ with this life event (as a process) largely via differentforms of social interaction. The chosen methodology was designed to elicit this type ofknowledge drawing on different disciplinary interpretations of coping strategies. Althoughunintended or early pregnancy in young women has developed as a key social developmentconcern in recent years (Hainsworth 2002; Mahy 2002; Westoff 2003; UNFPA 2007), thisresearch indicates that policy strategists in Mozambique struggle to develop adequate andeffective intervention in response. The narratives shared by young women, and the analysisdeveloped through chapters four to seven builds a complex picture for intervention, as familyrelationships remain a major factor for social and economic well-being. The socially andculturally constructed nature and predominant location within families mean that macrostrategies and community level intervention has limited impact during unintended pregnancy.Strengthening relational strategies (both formal and informal) through social developmentintervention is therefore necessary for young women to access social and organisationalresources for coping and social well-being. By using the concept of coping strategies, thejuxtaposition of ‘copers’ and ‘non-copers’, the relationship between agency and structure, thestrategies employed at different levels, the significance of social interaction and coping as aprocess has been opened up to scrutiny. This thesis not only evaluates and critiques modelsof social development, but also argues that the concept of coping strategies can be usefullyapplied to inform social development in ways that address both individual and collective wellbeing

    Early presynaptic and late postsynaptic components contribute independently to Brain-Derived Neurotrophic Factor-induced synaptic plasticity

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    Trophin-induced synaptic plasticity consists of both presynaptic and postsynaptic processes. The potential interdependence of these mechanisms and their temporal relationships are undefined. The synaptic vesicle protein Rab3A is required for the early, initial 10 min phase, but not for the later phase of BDNF-enhanced transmission. We now examine the temporal distinction and mechanistic relationships between these phases of BDNF action. Rab3A mutant cells did not exhibit increased mEPSC frequency in response to BDNF in cell culture, indicating absence of the presynaptic component. In contrast, BDNF enhanced post-synaptic glutamate-induced current in the mutant neurons as in the wildtype, indicating that the postsynaptic component of the response was intact. Finally, the postsynaptic NMDA receptor subunit NR2B was phosphorylated at Tyr1472 by BDNF in Rab3A knockouts, as previously shown in wildtype. Our results are the first to demonstrate that presynaptic and postsynaptic components of BDNF-enhanced synaptic activity are independent and temporally distinct.Peer reviewe
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