47,937 research outputs found

    Dr. Lin Sun, CAU, March 2013

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    This video is a conversation with Dr. Lin Sun. Dr. Sun talks about an exhibit at the Woodruff Library titled "At The Boundary." Jordan Moore, AUC Woodruff Library, is the interviewer

    An Analysis of <i>Judge Lin</i>

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    Biography of Lin Wen Zhong Gong has another way to call, that is Judge Lin. The leading character is Lin Ze-Xu. This book is based on functionary experience of Lin Ze-Xu, with the captivating plots of court case, helping by highly skilled military attach\uc3\ua9s and chivalrous knights, and the history facts of Opium War. It makes Lin Ze-Xu\ue2s Confucian temperament and tragic mood more, also contrasts with author\ue2s sorrow and furiousness for the politics at the time. History, court case, martial arts\ue2\ua6\ue2\ua6etc. are essence of this book and it broadens the way of this writing style. The topic of the thesis is \ue2An Analysis of Judge Lin\ue2. The following thesis will be divided into six different chapters. The introduction is Chapter one of the thesis, which is including researching motive and purpose, literature review of predecessors, researching version by existing information, raising questions, choosing research methods and arranging chapters. In chapter Two, I discuss the study of characters of Lin Ze-Xu, also makes a deep analysis of author\u27s purpose of writing him. In chapter Three, I analyze supporting actors and actress. Meanwhile, I illustrate author\u27s purpose of writing supporting actress because the author had different manner to describe supporting actress. Moving to the Chapter Four, I mainly focus on the plots of Judge Lin, and organize cases of Lin Ze-Xu and his subordinates to understand features of cases. In Chapter Five, I represent the causes of Opium War. China and England had difference of opinions of opium. Therefore, it is easier to comprehend what the author\u27s purpose is. In the last chapter I summarize the main points of the preceding chapters and confirm particularity of Judge Lin

    The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing

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    Lin-41 is a stem cell-specific E3 ligase and a known target of the tumour suppressor microRNA (miRNA) let-7. Lin-41 was recently reported to mediate ubiquitylation and degradation of the miRNA pathway protein Ago2. We demonstrate that Lin-41 is over-expressed in hepatocellular carcinoma (HCC). Lin-41 over-expression correlates with high a-fetoprotein level, high tumour grade and high tumour stage and predicts early tumour recurrence. Lin-41 is a strong predictor of poor long-term survival for patients with HCC. Lin-41 knock-down by RNA interference in HCC cell lines Huh7 and Hep3B suppressed proliferation in vitro and reduced in vivo tumour growth in NOD/SCID mice. On the other hand, over-expression of Lin-41 in the HCC cell line SK-Hep1 enhanced tumourigenicity. Over-expression and knock-down of Lin-41 led to inverse changes in the levels of Ago1 and Ago2 proteins. Over-expression of Ago1 and Ago2 reduced in vivo tumour growth. Lin-41 over-expression suppressed let-7 activity in HCC cell lines and expression of Lin-41 enhanced the expression of let-7-regulated oncogenes c-Myc, Lin-28B, HMGA2 and type 1 insulin-like growth factor receptor (IGF1R). Expression of Lin-28B and c-Myc enhanced the expression of Lin-41. Chromatin immunoprecipitation and reporter assays revealed direct association of c-Myc with the Lin-41 promoter, resulting in transcriptional transactivation. Our results indicate that Lin-41 plays an important role in the growth of HCC by regulating RISC complex proteins Ago1 and Ago2 to inhibit miRNA-mediated gene silencing and promote the expression of oncogenic proteins. Lin-41 is also a strong prognostic factor for patients with HCC. Copyright (C) 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd

    Society of Composers Region VI Conference - Concert 2 Thursday. February 9. 2006 8:00 p.m. Lillian H. Duncan Recital Hall

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    Program: Falling through Crimson and Lead / Suzanne Sorkin -- Madison Sketchbook / John G. Bilotta -- Nocturne No.3 / Francisco Castillo Trigueros -- Schematic Nocturne / Bruce Bennett -- Turning / Derek Bermel -- Once It Was / Trent Hanna -- Interaction / Mei-Fang Lin -- Dialogue for two pianos / Florie Namir.No program is available for this performance

    "Third Generation"-Type Functional Tris(2-pyridyl)borate Ligands and their Transition-Metal Complexes

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    Phenyltris(2-pyridyl)borates (Tpyb) are a promising class of tripodal “scorpionate”-type ligands with potential utility in the development of transition metal complexes with interesting optical, electronic or magnetic properties, and as building blocks to metallosupramolecular polymers. We report here a new class of “third generation”-type Tpyb ligands that contain different functional groups attached to the boron-bound aryl moiety. The synthesis, characterization and metal ion complexation behavior of ligands with iodo and trimethylsilyl groups is discussed. The electrochemical and absorption characteristics of the corresponding low-spin Fe(II) and Ru(II) complexes are compared. We demonstrate the further elaboration of the iodo derivatives with alkynes via Sonogashira-Hagihara coupling, a process that proceeds with high yield for the Fe(II) and Ru(II) complexes, but not for the free ligand. The borylation of the silyl-substituted Ru(II) complex with BBr3 was also investigated. In addition to the expected borylation product, Ru(Tpyb-Bpin)2, the replacement of one (major product) or two phenyl groups is observed, suggesting that electrophilic borylation occurs at both the C(Ph)-Si and the C(Ph)-B aromatic carbons. The successful attachment of a range of different functional groups at the periphery of the Tpyb metal complexes is expected to provide opportunities to access new polymeric materials via C-C coupling or click-type reactions.Peer reviewe

    Macrocephenchelys nigriventris Lin, Shao & Smith

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    * Macrocephenchelys nigriventris Lin, Shao & Smith, this volume Macrocephenchelys nigriventris Lin, Shao & Smith, 2018: this volume. (type locality: Nan-fang-ao, Yilan, northeastern Taiwan). Remarks. Newly described in this volume by Lin et al. (2018). This species is commonly collected from off northeastern and southwestern Taiwan, by bottom trawl.Published as part of Ho, Hsuan-Ching, Smith, David G., Tighe, Kenneth A., Hibino, Yusuke & Mccosker, John E., 2018, Checklist of eels of Taiwan (orders Anguilliformes and Saccopharyngiformes): An update, pp. 5-17 in Zootaxa 4454 (1) on page 12, DOI: 10.11646/zootaxa.4454.1.3, http://zenodo.org/record/144668

    Cleruchoides Lin & Huber 2007

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    Cleruchoides Lin & Huber, 2007. Not illustrated.Published as part of Huber, John T., Bolte, Klaus & Read, Jennifer D., 2023, The morphological diversity of Mymaridae (Hymenoptera): an atlas of scanning electron micrographs. Part 1. General overview and structure of the head, pp. 1-100 in Zootaxa 5273 (1) on page 26, DOI: 10.11646/zootaxa.5273.1.1, http://zenodo.org/record/789251

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Lowest electronic states of neutral and ionic LiN

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    We have investigated the potential energy curves (PECs) of the LiN heteronuclear diatomic molecule, including its ionic species LiN+ and LiN−, using explicitly correlated multi-reference configuration interaction (MRCI-F12) calculations in conjunction with the correlation consistent quintuple- basis set. The effect of core–valence correlation, scalar relativistic effects, and the size of the basis sets has been investigated. A comprehensive set of spectroscopic constants determined based on the above-mentioned calculations are also reported for the lowest electronic states and all systems, including dissociation energies, harmonic and anharmonic vibrational frequencies, and rotational constants. Additional parameters, such as the dipole moments, equilibrium spin-orbit constants, excitation energies, and rovibrational energy levels, are also documented. We found that the three triplet states of LiN, namely, X 3∑−, A 3Π, and 2 3∑−, exhibit substantial potential wells in the PEC diagrams, while the quintet states are repulsive in nature. The ground state of the anion also shows a deep potential well in the vicinity of its equilibrium geometry. In contrast, the ground and excited states of the cation are very loosely bound. Charge transfer properties of each of these states are also analyzed to obtain an in-depth understanding of the interatomic interactions. We found that the core–valence correlation has a substantial effect on the calculated spectroscopic constants.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Atmospheric Remote Sensin

    Parastethynium Lin & Huber 2011

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    Parastethynium Lin & Huber, 2011. Papua New Guinea, West New Britain, Dami Oil Palm Research Station. Figs A56, B52, C57, D58, E52, F54a,b (all P. maxwelli (Girault)).Published as part of Huber, John T., Bolte, Klaus & Read, Jennifer D., 2023, The morphological diversity of Mymaridae (Hymenoptera): an atlas of scanning electron micrographs. Part 1. General overview and structure of the head, pp. 1-100 in Zootaxa 5273 (1) on page 28, DOI: 10.11646/zootaxa.5273.1.1, http://zenodo.org/record/789251
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