153,859 research outputs found
The politics of fashion: perceptions of power in female clothing and ornamentation as reflected in the sixteenth-century Chinese novel Jin Ping Mei
No full textThis thesis examines issues of female power and influence in sixteenth-century China focusing on how women and their roles were perceived in the changing social environment of the mid-late Ming dynasty. Using aspects of a New Historicist approach, information from contemporary literary and historical sources are analysed alongside each other. With its emphasis on the lives of women and preoccupation with the description of material objects, the late Ming novel Jin Ping Mei forms an important element in the thesis. China in the sixteenth century saw expanding urbanisation, the emergence of a new wealthy merchant class, increasing visibility of women and a questioning of traditional morality. Fashion consciousness, as one of the most conspicuous aspects of the new material culture, is a possible indicator of these trends. Traditional Western theories contend that fashion began in the particular context of Renaissance Europe. However, this study argues that a similar fashion awareness existed in China too, and was manifested in a competitive striving for social status, in this case specifically among women. In contrast to previous studies which downplayed the impact women had on defining traditional Chinese culture, this thesis demonstrates how women and their sartorial choices began to redefine the boundaries of material culture, influencing literati discourse which, in turn, re- influenced female behaviour
Bembecia sophoracola Xu et Jin 1999
No full textBembecia (s. str.) sophoracola Xu et Jin, 1999 “ Bembecia sophoracola Xu et Jin, 新种 ”— Xu & Jin in: Xu et al. 1999: 9, fig. 2. Type locality: “ Ningxia (Yinchuan), …” [= China: Ningxia Hui, Yinchuan]. Holotype ♂ (CQAX). Bembecia sophoracola — Pühringer & Kallies 2004: 35; Jin et al. 2008: 515. Host plant. Sophora flavescens var. galegoides (Pall.) DC. (Fabaceae) (Xu et al. 1999). Distribution. China: Ningxia.Published as part of Gorbunov, Oleg G., Krupitsky, Anatoly V. & Marusov, Anatoly A., 2017, A new species of Bembecia from China, with a catalogue of Chinese species of the genus (Lepidoptera: Sesiidae), pp. 559-575 in Zootaxa 4273 (4) on page 571, DOI: 10.11646/zootaxa.4273.4.6, http://zenodo.org/record/80379
Uniformly accurate diffusive relaxation schemes for multiscale transport equations
No full textMany transport equations, such as the neutron transport, radiative transfer, and transport equations for waves in random media, have a diffusive scaling that leads to the diffusion equations. In many physical applications, the scaling parameter (mean free path) may differ in several orders of magnitude from the rarefied regimes to the hydrodynamic (diffusive) regimes within one problem, and it is desirable to develop a class of robust numerical schemes that can work uniformly with respect to this relaxation parameter. In an earlier work [Jin, Pareschi, and Toscani, SIAM J. Numer. Anal., 35 (1998), pp. 2405--2439] we handled this numerical problem for discrete-velocity kinetic models by reformulating the system into a form commonly used for a relaxation scheme for conservation laws [Jin and Xin, Comm. Pure Appl. Math., 48 (1995), pp. 235--277]. Such a reformulation allows us to use the splitting technique for relaxation schemes to design a class of implicit, yet explicitly implementable, schemes that work with high resolution uniformly with respect to the relaxation parameter. In this paper we show that such a numerical technique can be applied to a large class of transport equations with continuous velocities, when one uses the even and odd parities of the transport equation
FIGURE 1. Neottia bicallosa X.H. Jin. A. Habit. B in A new species of Neottia (Orchidaceae, Epidendroideae) from southwestern China
No full textFIGURE 1. Neottia bicallosa X.H. Jin. A. Habit. B. Front view of flower. C. Dorsal sepal. D. Lateral sepal. E. Petal. F. Lip. G. Ovary and column. (All drawn from the holotype by Sun, Y.B.)Published as part of Jin, Xiao-Hua, 2014, A new species of Neottia (Orchidaceae, Epidendroideae) from southwestern China, pp. 188-190 in Phytotaxa 177 (3) on page 189, DOI: 10.11646/phytotaxa.177.3.8, http://zenodo.org/record/514472
Sung-Ho Jin
No full text학위논문(박사)--아주대학교 일반대학원 :의학과,2014. 2ABSTRACT ⅰ
TABLE OF CONTENTS ⅲ
LIST OF FIGURES ⅴ
LIST OF TABLES ⅶ
Ⅰ. INTRODUCTION 1
A. Gastric Cancer and Malignant Ascites 1
B. Intraperitoneal Radioimmunotherapy 3
C. Purpose of the Study 6
Ⅱ. MATERIALS AND METHODS 7
A. Materials 7
1. Cell Lines 7
2. Subcutaneous Tumor and Malignant Ascites Mouse Models 7
3. Preparation of Radioimmunoconjugates 8
B. Methods 10
1. Western Immunoblot Analysis 10
2. Flow Cytometry Analysis 11
3. In vitro Cytotoxicity of Cetuximab 12
4. Immunofluorescence Microscopy 12
5. In vitro Stability Study of 64Cu-DOTA-Bn-NCS-Cetuximab 13
6. Immunoreactivity Assay 13
7. MicroPET Imaging 14
8. Biodistribution Studies 15
9. Peritoneal Membrane Autoradiography 15
10. Statistical Analysis 16
Ⅲ. RESULTS 17
A. EGFR Expression Levels in Gastric Carcinoma Cells 17
B. Subcellular Localization of Cetuximab-bound EGFR 19
C. Cetuximab Cytotoxicity in Gastric Cancer Cells 20
D. Conjugation and 64Cu Labeling 21
E. In Vitro Properties of 64Cu-DOTA-Cetuximab 23
F. Bilateral Subcutaneous Tumor and Malignant Ascites Mouse Models 26
G. PET Imaging of Bilateral Subcutaneous Tumor Model Mice 28
H. Biodistribution of 64Cu-DOTA-Cetuximab in Bilateral Subcutaneous Tumor Model Mice 29
I. EGFR expression level affected by incubation periods 33
J. PET Imaging of Malignant Ascites Model Mice after I.V. or I.P. Administration of 64Cu-DOTA-Cetuximab 35
K. Biodistribution of 64Cu-DOTA-Cetuximab in Malignant Ascites Model after I.V. or I.P. Administration 37
L. Localization of 64Cu-DOTA-Cetuximab in Peritoneal Seeding 43
Ⅳ. DISCUSSION 44
Ⅴ. CONCLUSION 49
REFERENCES 50
국문요약 61MasterIntraperitoneal (i.p.) radioimmunotherapy (RIT) may be a promising treatment strategy for intraperitoneally-confined malignant diseases including malignant ascites (MA) in gastric cancer. We conducted a comparative biodistribution study of 64Cu-DOTA-cetuximab in subcutaneous (SQ) tumor and MA mouse models.
A mouse xenograft model of bilateral SQ tumors that express epidermal growth factor receptor (EGFR) was established by SQ injections of NUGC-4 and MKN-45 gastric cancer cells into either shoulder of female BALB/c nude mice. The MA model was produced by i.p. injection of NUGC-4 cells. Cetuximab was conjugated to a bifunctional chelator (p-SCN-Bn-DOTA) and labeled with Copper-64 (T1/2 = 12.7 hours). Radiolabeled cetuximab was then administered intravenous (i.v.) or i.p. injection. Positron emission tomography (PET) imaging and biodistribution studies were conducted at the indicated time points.
In the bilateral SQ tumor model, the peak uptake of radiolabeled cetuximab in the NUGC-4 and MKN-45 tumors was detected at 24 h post-injection of 64Cu-DOTA-cetuximab by PET imaging and biodistribution analysis. NUGC-4 tumor uptake of radiolabeled cetuximab was significantly higher than MKN-45 tumor uptake at all time points. The EGFR expression levels of the two cell lines were similar according to in vitro experiments. However, based on flow cytometry analyses at different incubation times with primary antibody (cetuximab) ranging from 3 min to 3 h, the EGFR expression levels were increased over time, and the increasing slope was higher in NUGC-4 cells than in MKN-45 cells.
In the i.v.-induced MA model mice, the biodistribution of radiolabeled cetuximab in the blood pool and liver was high at 1 h and 3 h after i.v. injection and decreased over time. In the i.p.-induced MA model mice, the percent injected dose per gram (% ID/g) of ascites was very high and more than 8% at 1, 3, 24, and 48 h post injection; however, the % ID/g in all normal organs was equal to or less than 6% at all time points. In addition, all peak uptakes of normal organs and i.p.-induced NUGC-4 tumors appeared at 24 h after injection. In addition, the uptake ratios of tumor, peritoneum, and ascites to normal organs after i.p. injection were greater than after i.v. injection, particularly at the early time points. Finally, autoradiography studies using excised peritoneum and mesentery indicated several hot spots corresponding to peritoneal seeding.
The results suggest that using the i.p. route for RIT in malignant ascites models shows advantages over the i.v. route with regard to tumor targeting and half-life prolongation of radioimmunoconjugates in the peritoneal cavity
Neenchelys parvipectoralis Chu, Wu & Jin 1981
No full textNeenchelys parvipectoralis Chu, Wu & Jin, 1981 AR*ª Neenchelys parvipectoralis Chu, Wu & Jin, 1981: 24 (type locality: Pingtan Island, Fujian Province, China). Ho et al., 2010: 29, table 1; Ho et al., 2013: 11. Remarks. A very common species in the South China Sea, including southwestern Taiwan and Vietnam.Published as part of Ho, Hsuan-Ching, Smith, David G., Mccosker, John E., Hibino, Yusuke, Loh, Kar-Hoe, Tighe, Kenneth A. & Shao, Kwang-Tsao, 2015, Annotated checklist of eels (orders Anguilliformes and Saccopharyngiformes) from Taiwan, pp. 140-189 in Zootaxa 4060 (1) on page 170, DOI: 10.11646/zootaxa.4060.1.16, http://zenodo.org/record/24365
Geoffmonteithia queenslanda Jin, de Keyzer et Slipinski 2020
No full textGeoffmonteithia queenslanda Jin, de Keyzer et Ślipiński, 2020 (Figs. 11 H–J, 14J, 15L, 17E) Geoffmonteithia queenslanda Jin, de Keyzer et Ślipiński, 2020: 21. TL: Townsville, QLD. Holotype in ANIC (examined). Diagnosis. This species is morphologically similar to Pseudoplites and Eurynassa. Male can be separat- ed from P. hamali by its antennomere 3 not thicker than the following segments, the tibiae without lateral spines, and protarsi without long hairs. Female of G. queenslanda can be separated from P. hamali by its dense and coarse punctures on pronotum. Both sexes can be distinguished from Eurynassa species by having elongate antennomere 3 and prominent posteri- or angles on pronotum. Type. Geoffmonteithia queenslanda Jin, de Keyzer et Ślipiński, Holotype male deposited in ANIC, with the following labels “QLD: Townsville, 29 September 1995, Woodger T. | ANIC 25-067089 ”. Material examined (Fig. 17E). Queensland: AM (1 ♂): 5km N Leyburn, Dec. 1987, A. and G. Daniels; ANIC (3 ♂♂): Eidsvold, Dec. 1965, J. Bancraft; Townsville, Sep. 1995, T. Woodger; Yeppoon, Nov. 1965, Le Souef; QDPC (1 ♂): Long Pocket, Indooroopilly, Brisbane, Nov. 1980, J.F. Donaldson; QM (2 ♂♂; 2 ♀♀): 2: Gympie; Boggimoss No. 21 via Taroom, Nov. 1996, G.B. Monteith; Dipperu, Nov. 1971, B. Baldwin; QVMAG (4 ♂♂; 2 ♀♀): 6: The Gap, Brisbane, {from Jan. 1994 to Dec. 1995}, S. Fearn. New South Wales: ANIC (1 ♂; 1 ♀): Stumpys Rd., Braemar S.F., Nov. 2016, R. de Keyz- er, A. Scott and Sundholm, A.; south boundary Fortis Creek NP., north of Grafton, Dec. 1998, Watkins; MV (1 ♂): Canowindra, Jan. 1956, F.E. Wilson. Molecular data. BioSample ID: SAMN11080875 (Holotype), SAMN11080889 (Paratype).Published as part of Jin, Mengjie, Keyzer, Roger De, Hutchinson, Paul, Pang, Hong & Ślipiński, Adam, 2020, A Review Of The Australian Macrotomini (Coleoptera: Cerambycidae: Prioninae), pp. 33-96 in Annales Zoologici 70 (1) on page 61, DOI: 10.3161/00034541ANZ2020.70.1.003, http://zenodo.org/record/377667
Leptoteratura (Rhinoteratura) kailingensis Jin 2020, sp. n.
No full text19) Leptoteratura (Rhinoteratura) kailingensis Jin sp. n. Holorype ♂ (left front and middle legs, right hind leg, antenna, maxillary palpi lost): BRITISH N. Borneo/ Tawau Quoin Hill/ Cocoa Res. Sta./ 24.IX.1962; Y. Hirashima/ Light Trap/ BISHOP Paratype 2♂: labeled as Holotype Paratype ♂: BRITISH. N. Borneo / Tawau Quoin Hill / 3–7.VII.1962; H. Holtmann / Light Trap / BISHOP Paratype 2♀: labeled as Holotype, except “ 20.IX.1962 ” Paratype ♀: labeled as Holotype, except “ 15–20.VII.1962 ” Paratype ♀: labeled as Holotype, except “ 18.IX.1962 ” Description. Body slender and tenuous, small size, typical appearance of the subgenus. Fastigium of vertex flat, thin, with slightly round apex, middle furrow distinct (Fig. 5a, b). Maxillary palpi lost. Pronotum disc flat with 2 fine whitish yellow stripes along lateral margins of disc (Fig. 5 a–c). Posterior margin of lateral plate slightly sinuate. Thoracic foramen medium size. Tegmina and hind wings long, far beyond end of hind femur. Fore leg with coxal spur moderate long. Hind tibia with 2 pairs of apical spurs. Male last tergite with posterior margin slightly concave in middle, epiproct not visible. Cerci symmetrical, long and flat lobe, basal part with a short process, apical half widened into laminal shape (Fig. 5d, e). Subgenital plate long with smooth posterior margin, styli short (Fig. 5e). Female subgenital plate short, broad transversely, ovipositor comparative short and thick, curved upwards near apical 1/3 (Fig. 5f, g). Measurements (mm). Body: ♂ 9.0, ♀ 8.1–10.4; Pronotum: ♂ 3.5, ♀ 3.6–4.7; Tegmina: ♂ 15.0, ♀ 15.6–17.0; Hind femora: ♂ 7.2, ♀ 7.0–8.8; Ovipositor: 4.6–4.8. Comparison. This species is similar to Leptoteratura (Rhinoteratura) pulchra Gorochov, 2008 (figs. 35–39) from Sabah, Borneo by male cerci and female subgenital plate, but male cerci is narrower and longer, female subgenital plate is broad and transverse. Etymology. Name in memory of Chinese Entomologist and Orthopterist, senior research fellow Mr. Xia, Kailing, master thesis supervisor of the first author, who passed away at age of 98.Published as part of Jin, Xingbao, Liu, Xianwei & Wang, Hanqiang, 2020, New taxa of the tribe Meconematini from South-Pacific and Indo-Malayan Regions (Orthoptera, Tettigoniidae, Meconematinae), pp. 1-53 in Zootaxa 4772 (1) on pages 12-13, DOI: 10.11646/zootaxa.4772.1.1, http://zenodo.org/record/381411
Gahrliepia (Gahrliepia) cangshanensis Ren, Guo, Jin, Wu and Fletcher 2014
No full textGahrliepia (Gahrliepia) cangshanensis Ren, Guo, Jin, Wu and Fletcher, 2014: PALPublished as part of Nielsen, David H., Robbins, Richard G. & Rueda, Leopoldo M., 2021, Annotated world checklist of the Trombiculidae and Leeuwenhoekiidae (1758 - 2021) (Acari: Trombiculoidea), with notes on nomenclature, taxonomy, and distribution, pp. 1-243 in Zootaxa 4967 (1) on page 22, DOI: 10.11646/zootaxa.4967.1.1, http://zenodo.org/record/474551
Does corruption relieve foreign investors of the burden of taxes and capital controls?
No full textIn a sample of fourteen source countries making bilateral investments in forty five countries, the author finds that taxes, capital controls, and corruption, all have large, statistically significant negative effects on foreign investment. Moreover, there is no robust support in the data for the"efficient grease"hypothesis - that corruption helps attract foreign investment by reducing firms'tax burden and the irritant of capital controls.International Terrorism&Counterterrorism,Capital Markets and Capital Flows,Decentralization,Fiscal&Monetary Policy,Economic Theory&Research,Economic Theory&Research,International Terrorism&Counterterrorism,Governance Indicators,National Governance,Capital Flows
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