1,721,162 research outputs found

    INSPIRING SCIENCE: JIM WATSON AND THE AGE OF DNA

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    Preface -- Acknowledgments -- Foreword / Matt Ridley -- James D. Watson's life and work: a timeline -- Sect. I. Origins -- Introduction: student days -- Phage days in Indiana / Renato Dulbecco -- Quiz kids / Gunther S. Stent -- Some early recollections of Jim Watson / Seymour Benzer -- Reprint: the properties of x-ray-inactivated bacteriophage. I. Inactivation by direct effect / James Dewey Watson -- Sect. II. Cambridge -- Introduction: talking and thinking -- Jim's cool reception among the British geneticists / Avrion Mitchison -- Recollections of Jim Watson / Naomi Mitchison -- Our work on virus structure -- Francis H.C. Crick / One day in the Cavendish (April 1, 1953) / Gerald Roland Pomerat -- Jim and Syd / Sydney Brenner -- A letter to Jim, January 14, 2002 / Max F. Perutz -- Monday morning quarterback / Elof Carlson -- "The night before Crickmas" / Rollin Hotchkiss - - Reprint: a structure for deoxyribose nucleic acid / J.D. Watson and F.H.C. Crick -- Reprint: genetical implications of the structure of deoxyribonucleic acid / J.D. Watson and F.H.C. Crick - - Reprint: the complementary structure of deoxyribonucleic acid / F.H.C. Crick and J.D. Watson -- 1953 Symposium -- Introduction: a day in June -- Memories of the 1953 symposium / Robert L. Sinsheimer, Julius Marmur, Charles Yanofsky, Louis Siminovitch, Frank Fenner, Roy J. Britten, Howard Green, Theodore T. Puck, Waclaw Szybalski, Joseph S. Gots, Hillary Koprowski -- Symposium on "viruses" / The Long-Islander article -- Letter to Max Delbruck / James D. Watson -- Reprint: The Structure of DNA / J.D. Watson and F.H.C. Crick -- Nobel banquet speech / James D. Watson -- Sect. III. Career scientist -- Introduction: Caltech, Cambridge, and Harvard -- Remembering Delbruck / James D. Watson -- Does RNA form a double helix? / Alexander Rich -- Flowers and phage / Joan Steitz -- On the edge: my time in Jim Watson's Lab / Benno Muller-Hill / When ribosomes were king / Alfred Tissieres -- It smells right. . . / Lionel V. Crawford -- Excerpt from Naturalist / Edward O. Wilson -- Growing Up Around Jim / Jeffrey H. Miller -- Seems simple, very hard to do / Mark Ptashne -- Watson at Harvard (1956- 1976) / Paul Doty -- Reprint: structure of small viruses / F.H.C. Crick and J.D. Watson -- Reprint: unstable ribonucleic acid revealed by pulse labelling of escherichia coli / F. Gros, H. Hiatt, W. Gilbert, C.G. Kurland, R.W. Risebrough, and J.D. Watson -- Sect. IV. Cold Spring Harbor -- Introduction: an emotional attachment -- Cold Spring Harbor 1958-1968: the years between Demerec and Watson / John Cairns -- Life with Jim / Norton D. Zinder -- CSHL in the sixties: a view from the trenches / Ann Skalka -- Reprint: Cold Spring Harbor Laboratory director's report, 1989 / James D. Watson -- Jim as a mentor, 1971-1974 / Phillip A. Sharp -- From development of yeast cells to human brain hemispheres / Amar J.S. Klar -- Big shoes to fill, with the laces untied / Bruce Stillman -- Just Jim / Michael Wigler -- Milestones and mentoring: how Jim Watson influenced a scientific career / Douglas Hanahan -- CSHL in transition / Raymond F. Gesteland -- Cold Spring Harbor and recombinant DNA / Thomas Maniatis -- Reprint: Origin of concatemeric T7 DNA / J.D. Watson -- Jim and the board: behind the scenes / Bayard Clarkson -- Vision, innovation, breadth, and strength / David L. Luke III -- Portraits: Robertson, Pulling, and Grace / James D. Watson -- A morning on the porch / Jim Eisenman - - An architect at the lab: some personal recollections / William Grover -- Sect. V. Genomes -- Introduction: managing the genome - - Dr. Watson goes to Washington / Bradie Metheny -- Jim Watson and the Human Genome Project / James B. Wyngaarden -- The colossus of codes / Robert Cook-Deegan -- Jim and the Japanese human genome project / Kenichi Matsubara -- Climbing the ladder of life: James D. Watson and the ELSI years / Nancy Wexler -- Sect. VI. Education - - Introduction: communicating science -- The pied piper at Harvard / David Botstein -- There is more yet to come / Arnold J. Levine - - What I have learned from Jim / Bruce M. Alberts -- On drawing molecules / Keith Roberts -- Education by the sea shore / Jan Witkowski and John Inglis -- Endnotes -- Bibliography / James D. Watson -- Inde

    Three men, including Jim Watson, examine saltgrass along a roadway in Colorado, 1955

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    Three men examine saltgrass along a roadside between Denver and Fort Collins, Colorado, in 1955. Jim Watson stooping. Saltgrass has been high mowed. Open car door and farm fields beyond.Photographer uncertain"Grass- Highway between Denver & Ft. Collins Saltgrass Berm Wilson"Image taken on Kodachrome.RoadsidesUtility turfCool semiari

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Jim Watson And The Theory Of Vibration-rotation Interaction

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    Based on the the Coriolis interaction conceived by Teller and Tisza (1932), the fundamental Wilson-Howard Hamiltonian (WHH), formulated in 1936\footnote{Wilson, Jr., E. B. \& Howard, J. B. 1936 J. Chem. Phys. 4, 260}, includes everything about the vibration-rotation interaction. Enormous technical advances followed both in vibrational and rotational spectroscopy and have produced extremely rich data. Then God sent us the genius Jim Watson to deeply study the WHH and harvest all its fruits in the most sublime and direct manner. \vspace{0.05in} Out of the many jewels Watson left us I single out three works. (1) The theory of the centrifugal distortion of asymmetric-top molecules (1966)\footnote{Watson, J. K. G. 1966 J. Chem. Phys. 45, 1360; 46, 1935; 1968 J. Chem. Phys. 48, 4517}: To solve the indeterminacy of centrifugal distortion constants of non-planar asymmetric tops, Watson discovered an angular momentum operator Px_xPy_yPz_z + Pz_zPy_yPx_x which commutes with the rotational Hamiltonian and produces an additional relation between centrifugal constants making the solutions possible. This is the most frequently quoted paper in the field of molecular spectroscopy. (2) Simplification of the WHH (1968)\footnote{Watson, J. K. G. 1968 Mol. Phys. 15, 479}: For the first term of rearranged WHH H = 1/2Σ\Sigma(Π\Piα_\alpha-π\piα_\alpha)μ\muαβ_{\alpha\beta}(Π\Piβ_\beta-π\piβ_\beta) Watson discovered commutation relation [π\piα_\alpha, μ\muαβ_{\alpha\beta}]=0. using absolutely beautiful tensor algebra, thus simplifying the Hamiltonian. This is the most fundamental work in the field of molecular spectroscopy and represents the triumph of tensor algebra. (3) Forbidden rotational transitions (1971)\footnote{Watson, J. K. G. 1971 J. Mol. Speectrosc. 40, 536}: The Δ\DeltaK=0 selection rule of a symmetric top molecule corresponds to cylindrical symmetry. Since the actual symmetry is C3_3 rather than cylindrical for say NH3_3, Δ\DeltaK=3 forbidden transitions are weakly allowed. Watson's theory showed that non-polar molecules such as CH4_4 and H3+_3^+ are polar in some rotational levels and undergo forbidden rotational transitions. This theory has greatly influenced molecular astrophysics. \footnote{e.g. Oka, T., Geballe, T. R., Goto, M., Usuda, T., McCall, B. J., \& Indriolo, N. 2019 ApJ, 883, 54}Made available in DSpace on 2021-09-24T21:09:01Z (GMT). No. of bitstreams: 2 5264.pdf: 21987 bytes, checksum: 5508c59192d92ba4cf46faab2c626752 (MD5) license.txt: 4802 bytes, checksum: 58353f9dd6876860dd5221f3d7872a95 (MD5) Previous issue date: 2021-06-23Made available in DSpace on 2022-01-21T16:09:31Z (GMT). No. of bitstreams: 4 5264.pdf.txt: 2362 bytes, checksum: 612c5c8a20b11ff007545edf681e136d (MD5) license.txt: 4802 bytes, checksum: 58353f9dd6876860dd5221f3d7872a95 (MD5) 5264.pdf: 21987 bytes, checksum: 5508c59192d92ba4cf46faab2c626752 (MD5) WK04_5264.pdf: 69615 bytes, checksum: 5e8abc729d7f7f557610d5c6761558a4 (MD5) Previous issue date: 2021-06-2
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