5,775 research outputs found
William E. Hoy, letter to Mr. Ralph Elliot Lin Weber, July 8, 1943, with envelope and newspaper articles
No full textThis letter was sent from William E. Hoy to Mr. Ralph Elliot Lin Weber and is dated July 8, 1943. The letter recounts information about the only baseball game where Hoy, a deaf athlete, was at-bat against Taylor, also a deaf athlete. Mentioned in the letter is a typewritten play by play of the same game, copied from the Enquirer of May 17, 1902. Also included is an envelope and newspaper articles. The envelope, from International League Information, is addressed to Ralph E Lin Weber and has handwritten lists of players of N.Y. and Cincinnati. The newspaper articles are from the Dayton Daily News and the Cincinnati Enquirer and feature pictures of William E. Hoy, the author of the letter
Does Downloading PowerPoint Slides Before the Lecture Lead to Better Student Achievement?: Reply
No full textThis reply responds to a comment by Cannon (2011) that opens the debate on consistency of the effect of downloading PowerPoint slides before lectures on students’ exam performance. Cannon (2011) points out potential endogeneity problems in Chen and Lin (2008) and attempts to explore the unconditional mean effect of downloading PowerPoint slides for the full sample. In this reply, we firstly argue that the estimates in our original article are consistent since the effect of interest is the “conditional†treatment effect but not the unconditional mean effect. We provide explanations for our rationale of estimating the “conditional†treatment effect. Secondly, we propose a modified downloading variable to replicate Cannon’s analysis. Our results suggest that downloading PowerPoint slides before the exam does not produce a significant effect on absent students’ exam performance which is different from the results in Cannon (2011). Our analysis does support Cannon’s argument that students fixed effects are different across different attendance status.
Author Co-Citation Analysis (ACA): a powerful tool for representing implicit knowledge of scholar knowledge workers
No full textIn the last decade, knowledge has emerged as one of the most important and valuable organizational assets. Gradually this importance caused to emergence of new discipline entitled ―knowledge management‖. However one of the major challenges of knowledge management is conversion implicit or tacit knowledge to explicit knowledge. Thus Making knowledge visible so that it can be better accessed, discussed, valued or generally managed is a long-standing objective in knowledge management. Accordingly in this paper author co- citation analysis (ACA) will be proposed as an efficient technique of knowledge visualization in academia (Scholar knowledge workers)
lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulva development
No full textLate events in the cell-cell signalling pathway that controls the specification of vulva cell fates in C. elegans are characterized. The lin-31 gene acts downstream of the ras homolog let-60 and encodes a member of the HNF-3/fork head family of DNA-binding transcription factors. lin-31 regulates how vulval precursor cells choose their fate and in lin-31 mutants, these cells do not properly choose which fate to express and therefore adopt any of the 3 possible vulval cell fates in a deregulated manner..RE: 68 ref.; SC: CA; PE; 0TSource type: Electronic(1) http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0890-9369&isbn=&volume=7&issue=6&spage=933&pages=933-947&date=1993&title=Genes%20and%20Development&atitle=lin-31%2c%20a%20Caenorhabditis%20elegans%20HNF-3%2ffork%20head%20transcription%20factor%20homolog%2c%20specifies%20three%20alternative%20cell%20fates%20in%20vulva%20development.&aulast=Miller&pid=%3Cauthor%3EMiller%2c%20L%20M%3bGallegos%2c%20M%20E%3bMorisseau%2c%20B%20A%3bKim%2c%20S%20K%3C%2Fauthor%3E%3CAN%3E19932337278%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3
Tagging of Biomedical Articles on CiteULike: A Comparison of User, Author and Professional Indexing
No full textThis paper examines the context of online indexing from the viewpoint of three different groups: users, authors, and professional indexers. User tags, author keywords and descriptors were collected from academic journal articles, which were both indexed in Pubmed and tagged on CiteULike, and analysed. Descriptive statistics, informetric measures, and thesaural term comparison shows that there are important differences in the use of keywords between the three groups in addition to similarities which can be used to enhance support for search and browse. While tags and author keywords were found that matched descriptors exactly, other terms which did not match but provided important expansion to the indexing lexicon were found. These additional terms could be used to enhance support for searching and browsing in article databases as well as to provide invaluable data for entry vocabulary and emergent terminology for regular updates to indexing systems. Additionally, the study suggests that tags support organisation by association to task, projects and subject while making important connections to traditional systems which classify into subject categories
Media literacy of government leaders in the e-government era
No full textWith the development of globalization and information technology, the process of government management is become more and more digital. E-government has become an inevitable choice of public management, leading to the high demand for media literacy of government leaders. Leaders should not only have high levels of professional ability and moral quality, but also need excellent media literacy to spread the latest thoughts of government leadership. Media literacy of government leaders includes three parts: network governance (NG), propaganda on party building and regulate the network of democracy. Based on the investigation of current government leaders' media literacy, the author finds that government leaders' media literacy still needs to be further improved. This paper provides the following recommendations: (1) adhering to people-oriented ideology, (2) perfecting the training and appointive mechanism of government leaders, (3)combine government leaders' media literacy with human resource management process (e.g. selection, recruitment, performance evaluation), (4)strengthen the party's construction and management of media
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
No full textGenetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy. To determine whether vascular endothelial growth factor A (VEGF-A) produced by tumor-associated macrophages regulated the onset of the angiogenic switch, a genetic approach was used to restore expression of VEGF-A into tumors at the benign stages. This stimulated formation of a high-density vessel network and in macrophage-depleted mice, was followed by accelerated tumor progression. The expression of VEGF-A led to a massive infiltration into the tumor of leukocytes that were mostly macrophages. This study suggests that macrophage-produced VEGF regulates malignant progression through stimulating tumor angiogenesis, leukocytic infiltration and tumor cell invasion
A Connectionist and Multivariate Approach to Science Maps: Som, Clustering and Mds Applied to Library & Information Science Research.
No full textThe visualization of scientific field structures is a classic of scientometric studies. This paper presents a domain analysis of the library and information science discipline based on author co-citation analysis (ACA) and journal cocitation analysis (JCA). The techniques used for map construction are the self-organizing map (SOM) neural
algorithm, Ward’s clustering method and multidimensional
scaling (MDS). The results of this study are compared with
similar research developed by Howard White and Katherine
McCain [1]. The methodologies used allow us to confirm that
the subject domains identified in this paper are, as well,
present in our study for the corresponding period. The appearance of studies pertaining to library science reveals
the relationship of this realm with information science.
Especially significant is the presence of the management on the journal maps. From a methodological standpoint, meanwhile, we would agree with those authors who consider
MDS, the SOM and clustering as complementary methods
that provide representations of the same reality from different analytical points of view. Even so, the MDS representation is the one offering greater possibilities for the structural representation of the clusters in a set of variables
ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice
No full textThere is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries. This disparity suggests an environmental contribution to cancer resistance in endemic populations. Enterotoxigenic bacteria associated with diarrheal disease are prevalent in developing countries, including enterotoxigenic E. coli (ETEC) producing heat-stable enterotoxins (STs). STs are peptides that are structurally homologous to paracrine hormones that regulate the intestinal guanylyl cyclase C (GUCY2C) receptor. Beyond secretion, GUCY2C is a tumor suppressor universally silenced by loss of expression of its paracrine hormone during carcinogenesis. Thus, the geographic imbalance in colorectal cancer, in part, may reflect chronic exposure to ST-producing organisms that restore GUCY2C signaling silenced by hormone loss during transformation. Here, mice colonized for 18 weeks with control E. coli or those engineered to secrete ST exhibited normal growth, with comparable weight gain and normal stool water content, without evidence of secretory diarrhea. Enterotoxin-producing, but not control, E. coli, generated ST that activated colonic GUCY2C signaling, cyclic guanosine monophosphate (cGMP) production, and cGMP-dependent protein phosphorylation in colonized mice. Moreover, mice colonized with ST-producing E. coli exhibited a 50% reduction in carcinogen-induced colorectal tumor burden. Thus, chronic colonization with ETEC producing ST could contribute to endemic cancer resistance in developing countries, reinforcing a novel paradigm of colorectal cancer chemoprevention with oral GUCY2C-targeted agents
Mimela ruyuanensis , Lin 1990
No full text<i>Mimela ruyuanensis</i> Lin, 1990 <p>(Figs. 15A–E)</p> <p> <i>Mimela ruyuanensis</i> Lin, 1990: 24, fig. 11 [original description, type locality: Guangdong, Ruyuan]; Lin 1993: 57, fig. 42 (in text), pl. VII, fig. 55 & 56, pl. XV, fig. 41, pl. XXI, fig. 33 [redescription, <i>sericicollis</i> -group]; Zorn 2006: 269 [catalogued]; Krajčik 2007: 88 [catalogued]; Zorn & Bezděk 2016: 347 [catalogued].</p> <p> <b>Type material examined.</b> None. Type material was not located in SYSU (visited by the author, Dec. 2019). The identification is based on the original description and Lin (1993).</p> <p> <b>Additional material examined</b> (2♂♂, 1♀). 1♂ (CCPC), CHINA, Guangxi Province, Guilin City, Xing’an County, Gaozhai, 500~ 600m, V.21–23.2013, Yu-Feng Hsu leg.; 1♂, 1♀ (ZMPC), Guangxi, Xing’an County, Mount Maoershan 25~ 30-v-2011.</p> <p> <b>Remarks.</b> When describing <i>Mimela ruyuanensis</i>, Lin (1990) overlooked the closest sibling, <i>Mimela fruhstorferi</i> Ohaus, 1902 (Fig. 15F–K) from Mount Mauson, Vietnam. A male topotype of <i>M. fruhstorferi</i> examined by Carsten Zorn (personal communication 2019) confirms that they are allied but not conspecific as they possess different body color and shape of parameres. Males of <i>M. ruyuanensis</i> have purplish luster upon the reddish brown body, while females of both species are reddish brown (Lin 1990, 1993; Ohaus 1902). <i>Mimlea ruyuanensis</i> is recorded from Guangxi Province for the first time.</p> <p> <b>Distribution.</b> China: Guangdong, Guangxi *.</p>Published as part of <i>Zhao, Ming-Zhi, 2021, On the genus Mimela Kirby, 1823 (Coleoptera: Scarabaeidae: Rutelinae) from China and adjacent countries, with description of five new species, pp. 201-230 in Zootaxa 4995 (2)</i> on page 223, DOI: 10.11646/zootaxa.4995.2.1, <a href="http://zenodo.org/record/5056160">http://zenodo.org/record/5056160</a>
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