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    Pathological changes in the organs of mice model inoculated with Corynebacterium pseudotuberculosis organism

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    Corynebacterium pseudotuberculosis is a facultative, gram positive intracellular small club-shaped rod which produces lesions similar to those of tuberculosis. It is known worldwide to cause caseous lymphadenitis (CLA) in sheep and goats. CLA is characterized by the abscess formation in lymph nodes and/or visceral organs. In the recent outbreak of CLA in the TPU farm in UPM, it was reported that the CLA lesions were found in the visceral organs. In the present investigation, attempts were made to study the ethiopathogenesis of CLA in mice models which involved a comparison of clinical signs, haemogram and biochemistry, and histopathological changes in visceral organs between the diseased and non-diseased group. As an overall summary of this project, CLA in mice resulted in clinical signs, such as huddling together, dejection, anorexia, pasty faeces and accompanied by a rapid and shallow respiration pattern. For the haemogram and serum biochemistry profile, it showed a significant difference in the mean value between the diseased group and non-diseased group which include lymphocyte, plasma protein, monocyte, eosinophil, total bilirubin, total protein and potassium. Finally, the most pronounced histopathological changes in the visceral organs were septicaemia, with severe congestion and increased vascularization, together with the presence of capsulated abscess, micro-abscesses formation, infiltration of neutrophils and macrophages, tubercule granulomas, necrosis and early signs of degeneration in majority of the infected mice

    A Short Note: A study in determining the correlation between cortisol concentration in vaccinated and non-vaccinated clinically infected pneumonic goats

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    In Malaysia, pneumonic pasteurellosis is one of the major problems in the small ruminant industry. Small ruminants especially goats are more susceptible to the disease that usually occurs due to stressful conditions. Cortisol plays an important role in the disease development of pneumonic pasteurellosis. The main objective of this study was to determine the correlation between cortisol concentration in vaccinated and non-vaccinated pneumonic goats. A total of 15 normal goats and 9 clinically infected pneumonic goats were selected from 2 vaccinated farms, whereas 15 normal goats and 31 clinically infected pneumonic goats from 2 non-vaccinated farms were selected for this study. Goats with clinical signs of nasal discharges, coughing with crackle lung sound were diagnosed as pneumonic goats. Blood samples were collected from the selected goats for cortisol evaluation. The study revealed that non-vaccinated clinically infected pneumonic goats exhibited a slightly higher (p>0.05) cortisol value compared to the other experimental goats. Therefore, it can be concluded that the use of plasma cortisol concentration as a measure of stress contributing towards pneumonic pasteurellosis in goats might not be the best way to confirm the influences of the disease

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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