171,803 research outputs found
E Tohei, a New Zealand girl [picture].
No full textAttributed to Joseph Jenner Merrett by New Zealand researcher, 1989.; Rex Nan Kivell Collection NK4610.; Title from inscription bot. c.; T3202
Biophysical correlates of relative abundances of marine megafauna at Ningaloo Reef Western Australia
No full text© CSIRO 2007Changes in the relative abundance of marine megafauna (whales, dolphins, sharks, turtles, manta rays, dugongs) from aerial survey sightings in the waters adjacent to Ningaloo Reef between June 2000 and April 2002 are described. Generalised linear models were used to explore relationships between different trophic guilds of animals (based on animal sighting biomass estimates) and biophysical features of the oceanscape that were likely to indicate foraging habitats (regions of primary/secondary production) including sea surface temperature (SST), SST gradient, chlorophyll-a (Chl-a), bathymetry (BTH) and bathymetry gradient (BTHg). Relative biomass of krill feeders (i.e. minke whales, whale sharks, manta rays) were related to SST, Chl-a and bathymetry (model [AICc] weight = 0.45) and the model combining these variables explained a relatively large amount (32.3%) of the variation in relative biomass. Relative biomass of fish/cephalopod feeders (dolphins, sharks) were weakly correlated with changes in SST, whereas that of other invertebrate/macroalgal feeders (turtles, dugong) was weakly correlated with changes in steepness of the shelf (bathymetry gradient). Our results indicate that biophysical variables describe only a small proportion of the variance in the relative abundance and biomass of marine megafauna at Ningaloo reef.Jai C. Sleeman, Mark G. Meekan, Steven G. Wilson, Curt K. S. Jenner, Micheline N. Jenner, Guy S. Boggs, Craig C. Steinberg and Corey J. A. Bradsha
The ion-beam reactive sputtering process for deposition of niobium nitride thin films
No full textThesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1990.Vita.Includes bibliographical references (leaves 284-290).by Daniel Jenner Lichtenwalner.Ph.D
Dopamine D<sub>3</sub> receptors are not involved in the induction of c-<em>fos</em> mRNA by neuroleptic drugs: comparison of the dopamine D<sub>3</sub> receptor antagonist GR103691 with typical and atypical neuroleptics
No full textThe effect of acute and chronic administration of dopamine receptor antagonists on the expression of mRNA encoding the cellular immediate-early gene c-fos was investigated in rat brain by in situ hybridization using 35S-labelled oligonucleotide probes. The selective dopamine D3 receptor antagonist GR103691 had no effect on the level of c-fos mRNA after acute or chronic treatment. Acute treatment with haloperidol increased the level of c-fos mRNA in the caudate-putamen, nucleus accumbens shell and core, olfactory tubercle and parietal cortex. After chronic treatment with haloperidol increases in the level of c-fos mRNA in the caudate-putamen and nucleus accumbens core were no longer observed. The increase in the level of c-fos mRNA in the nucleus accumbens shell was attenuated but still significantly elevated above the level measured in vehicle-treated animals. In the olfactory tubercle, parietal cortex, frontal cortex and cingulate cortex the level of c-fos mRNA was decreased after chronic haloperidol treatment. Acute sulpiride treatment reduced the level of c-fos mRNA in the olfactory tubercle, parietal cortex and cingulate cortex. After chronic treatment with sulpiride the level of c-fos mRNA was reduced in the dorsal caudate-putamen only. Acute clozapine treatment increased the level of c-fos mRNA in the nucleus accumbens shell and islands of Calleja. After chronic treatment with clozapine the level of c-fos mRNA remained elevated in the islands of Calleja but not in the nucleus accumbens shell. These results indicate that acute and chronic blockade of dopamine D3 receptors does not cause induction of c-fos transcription in limbic, striatal or cortical regions of rat brain. This study also demonstrated that acute blockade of dopamine receptors with haloperidol, sulpiride and clozapine induced different regionally specific patterns of c-fos expression which were altered after chronic blockade.</p
Identification of multiple isoforms of soluble and granule-bound starch synthase in developing wheat endosperm
No full textK. Denyer, C. M. Hylton, C. F. Jenner, A. M. Smit
Markers for dopaminergic neurotransmission in the cerebellum in normal individuals and patients with Parkinson's disease examined by RT-PCR
No full textThe presence of neuronal elements that are indicative of dopaminergic neurotransmission in cerebellum suggest that this brain region may contribute to the motor symptoms or dyskinesia seen in Parkinson's disease. Reverse transcription polymerase chain reaction (RT-PCR) was used to examine the expression of markers for dopaminergic neurotransmission in the cerebellum from postmortem brain tissue obtained from normal subjects and patients dying with Parkinson's disease who were receiving treatment with dopaminergic drugs. Dopamine D1-3 receptors, tyrosine hydroxylase and dopamine transporter mRNA was detected in the uvula and nodulus (lobules 9 and 10, respectively) of the vermis of cerebellum from normal individuals. In Parkinson's disease, the level of dopamine D1 and D3 receptor mRNA was significantly reduced in lobule 9 and the level of tyrosine hydroxylase mRNA was significantly reduced in lobule 10. No alteration in the level of dopamine D2 receptor or dopamine transporter mRNA was found in either lobule in patients with Parkinson's disease. These results show that mRNA expression for the functional components of dopaminergic neurotransmission is present in human cerebellum. The discrete changes in the levels of dopamine D1 and D3 receptors and tyrosine hydroxylase mRNA in cerebellum from l-DOPA treated Parkinson's disease patients suggests that this brain area has a role in the symptoms of Parkinson's disease and/or the beneficial/side-effects of treatment.</p
Adenosine A<sub>2A</sub> receptor mRNA expression in Parkinson's disease
No full textThe expression of the human adenosine A2A receptor was examined by reverse transcription polymerase chain reaction in post-mortem human brain tissue that was obtained from normal subjects and patients who died with Parkinson's disease. Adenosine A2A receptor mRNA was detected in both striatal (nucleus accumbens, caudate nucleus and putamen) and extrastriatal (globus pallidus and substantia nigra) brain regions. A significant decrease in the level of adenosine A2A receptor mRNA was found in the anterior and posterior caudate nucleus and anterior dorsal putamen, whereas a significant increase was observed in the substantia nigra pars reticulata of Parkinsonian brain when compared to age-matched controls. No change in adenosine A2A receptor mRNA levels was seen in any other brain region examined. This study demonstrates that A2A receptor mRNA expression is altered in the basal ganglia of patients who died with Parkinson's disease and who were receiving treatment with dopaminergic drugs. The adenosine A2A receptor appears subject to regulation by dopaminergic systems in human brain, though these data do not permit a distinction to be made between the effects of neuronal degeneration or drug treatment. The adenosine A2A receptor may therefore form a target for the treatment of basal ganglia disease.</p
Heki, the Commander in Chief during the late war ... [picture].
No full textAttributed to J.J. Merrett by New Zealand researchers.; Inscription continues: He died of consumption in 1849, caused by a blow he received from his wife in a fit of jealousy.; Rex Nan Kivell Collection NK221.; Title from inscription bot. c.; T3193
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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