2,516 research outputs found
Miss Julie [program]
No full textRipa, Augustine; Meslin, Julie; Milet, Jeffrey; Hoelscher, Erica; Liu, Susan; Riley, Robert C.; Frankel, Barrett; Bergmann, Aaro
Corepressor effect on androgen receptor activity varies with the length of the CAG encoded polyglutamine repeat and is dependent on receptor/corepressor ratio in prostate cancer cells
No full textAbstract not availableGrant Buchanan, Eleanor F. Need, Jeffrey M. Barrett, Tina Bianco-Miotto, Vanessa C. Thompson, Lisa M. Butler, Villis R. Marshall, Wayne D. Tilley, Gerhard A. Coetze
The construction of Karen Karnak: The multi-author-function
No full textThis thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author
Bridging the Gap Through Collaboration: The ASU Library Barrett Honors College Peer Mentor Program
No full textThe transforming skills that lead to exceptional academic results are writing and research. While it is the role of academic librarians to provide the appropriate resources to facilitate research, arguably students are more willing to rely on their fellow students than professional library assistance. At Arizona State University’s Barrett, The Honors College, trained and motivated students are serving as Peer Mentors who assist student research needs without the "stigma" of asking a Librarian for help.
The panel discusses and elucidate components of a student-to-student peer program and cover comprehensive planning aspects of personnel, communication and workflow methodologies, interdisciplinary representation, and competency building activities. They will share training and work protocols, focusing on the evolution of the program from conceptualization through implementation. The presentation is an interactive conversation between the panelists (covering varying aspects and perspectives of the program) and the audience.Presented at the New Mexico Library Association / Mountain Plains Library Association (NMLA/MPLA) Joint Conference 2019 in Albuquerque, NM on October 31, 2019
Third annual meeting of the Federal Council of the Chambers of Manufactures of the Commonwealth of Australia, held at Adelaide, September 10, 11, 12, 1906 [picture].
No full textCondition: good.; Title from inscription on mount.; "Top Row - A. Barrett, A. Wunderlich, F. Lichtner, C. Anderson, P. H. Evans, J.C. Bowring, C. A. L. Loney, R. Aitken Pryor, Geo. T. Clarke, F.W. Kitchen. Bottom Row - R. Burns Cuming, Jeffrey Denniss, J. M. Reid, J. M. Joshua, R. Hogarth"--At foot of title.; "Ernest Gall" embossed--Lower right.; File number NLA/9630-1
An American Grrrl’s Fab Four: Beatles Fandom as Autoethnographic Framework
No full textThis reflective article considers how a lifetime of Beatles fandom constructed an autoethnographic framework for its author while writing a book about the band. In writing the first cultural history of the Beatles to foreground women’s experiences of them, the author suggests that this project was only possible through following the “red thread” of her own fandom, which predates a career in academia. As an American, second-generation fan, and former musician, she believes that an autoethnographic ethos was embedded in and helped structure the research and writing of the book—even if autobiographical references remained minimal within its pages.No Full Tex
O. A. C. Review Volume XLVI Issue 5, February 1934
No full textThe focus of this issue is the preparation for College Royal and recognizing its tenth anniversary. This month's agricultural article is a report from the Dominion Parasite Laboratory on the biological control of pests. Other articles provide an account of the activities of a stage manager and the development of the field of home economics at Macdonald College in Quebec. Campus news addresses the success of the 1934 Conversazione, the commemorating of the sixtieth anniversary of the founding of O. A. C., the attendance at the Canadian Author Lecture, and the successful productions of "The Apple Cart" and "Iolanthe". The Macdonald Institute column comments on the Conversat and women's athletics activities in basketball and the rifle club. The Alumni Record supplies alumni updates.EditorialTen Years of the RoyalRamblings on the RoyalBlame it on the stage managerBiological control of insect pests in CanadaNot for girls onlyCollege lifeLiterary sectionO. A. C. sportsfolioAlumni recordMacdonald newsLetters to the editoradvertisin
Neural correlates of processing valence and arousal in affective words
No full textPsychological frameworks conceptualize emotion along 2 dimensions, "valence" and "arousal." Arousal invokes a single axis of intensity increasing from neutral to maximally arousing. Valence can be described variously as a bipolar continuum, as independent positive and negative dimensions, or as hedonic value (distance from neutral). In this study, we used functional magnetic resonance imaging to characterize neural activity correlating with arousal and with distinct models of valence during presentation of affective word stimuli. Our results extend observations in the chemosensory domain suggesting a double dissociation in which subregions of orbitofrontal cortex process valence, whereas amygdala preferentially processes arousal. In addition, our data support the physiological validity of descriptions of valence along independent axes or as absolute distance from neutral but fail to support the validity of descriptions of valence along a bipolar continuum
Cycling on the Verge? Exploring the Place of Utility Cycling in Contemporary New Zealand Transport Policy
No full textEfforts to increase cycling as a mode of transport (utility cycling) occur at central, regional and local levels of government through a range of supportive strategies, research, and guidelines. Despite these efforts, utility cycling levels in New Zealand have remained persistently low. This thesis examines the apparent disparity between policy intent and policy result, using a discourse analytical approach. It examines how cycling is positioned in contemporary New Zealand transport policy documents, and explores whose priorities are shaping transport policy with what implications for utility cycling.
This study uses a critical discourse analysis (CDA) approach to analyse the land transport documents from across the institutions of government. The CDA approach, grounded in the work of van Dijk and Fairclough, draws on ideas from the interpretive tradition of discourse analysis, inspired by Foucault’s concepts of knowledge and power. This approach reveals the position of utility cycling by exposing the framing, dominant discourses, and discursive strategies that privilege certain transport objectives and activities over others.
The findings show transport is promoted almost exclusively by central government as an activity to facilitate economic growth and efficiency, despite its potential (and actual) impacts on health and well-being, social justice, and environmental sustainability. The discursive practices of the government privilege private motor vehicle use, helping to both legitimate and maintain that privilege at all levels of government, while positioning utility cycling as a marginalised mode of transport.
This thesis contributes to scholarship on utility cycling and land transport policy in New Zealand by identifying how the discursive strategies of government control the position of utility cycling in New Zealand. This study underscores the need for a central government-led, long-term strategic vision for a genuinely integrated, multi-modal transport system, in order for the benefits of utility cycling to be fully maximised
Nitric oxide in chemostat-cultured Escherichia coli is sensed by Fnr and other global regulators: unaltered methionine biosynthesis indicates lack of S nitrosation
No full textWe previously elucidated the global transcriptional responses of Escherichia coli to the nitrosating agent S-nitrosoglutathione (GSNO) in both aerobic and anaerobic chemostats, demonstrated the expression of nitric oxide (NO)-protective mechanisms, and obtained evidence of critical thiol nitrosation. The present study was the first to examine the transcriptome of NO-exposed E. coli in a chemostat. Using identical conditions, we compared the GSNO stimulon with the stimulon of NO released from two NO donor compounds {3-[2-hydroxy-1-(1-methyl-ethyl)-2-nitrosohydrazino]-1-propanamine (NOC-5) and 3-(2-hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine (NOC-7)} simultaneously and demonstrated that there were marked differences in the transcriptional responses to these distinct nitrosative stresses. Exposure to NO did not induce met genes, suggesting that, unlike GSNO, NO does not elicit homocysteine S nitrosation and compensatory increases in methionine biosynthesis. After entry into cells, exogenous methionine provided protection from GSNO-mediated killing but not from NO-mediated killing. Anaerobic exposure to NO led to up-regulation of multiple Fnr-repressed genes and down-regulation of Fnr-activated genes, including nrfA, which encodes cytochrome c nitrite reductase, providing strong evidence that there is NO inactivation of Fnr. Other global regulators apparently affected by NO were IscR, Fur, SoxR, NsrR, and NorR. We tried to identify components of the NorR regulon by performing a microarray comparison of NO-exposed wild-type and norR mutant strains; only norVW, encoding the NO-detoxifying flavorubredoxin and its cognate reductase, were unambiguously identified. Mutation of norV or norR had no effect on E. coli survival in mouse macrophages. Thus, GSNO (a nitrosating agent) and NO have distinct cellular effects; NO more effectively interacts with global regulators that mediate adaptive responses to nitrosative stress but does not affect methionine requirements arising from homocysteine nitrosation.</p
- …
