68 research outputs found
Quantitative Estimation of Yeast on Maxillary Denture in Patients with Denture Stomatitis and the Effect of Chlorhexidine Gluconate in Reduction of Yeast
No full textDenture stomatitis is a condition associated with wearing of a denture. The predisposing factor leading to denture stomatitis could be poor oral hygiene, ill-fitting denture and relief areas. Around 30 patients with denture stomatitis were advised to rinse with chlorhexidine gluconate mouthwash for 14 days and were directed to immerse the upper denture in the chlorhexidine solution for 8 hours. The samples were collected by scraping maxillary denture in saline at three intervals, prior to, at the end of 24 hours and after 14 days of treatment, then were inoculated and quantitative estimation of the yeast growth on Sabouraud′s dextrose agar plate was done. It was observed that after a period of 14 days, there was a reduction in the growth of yeast and also improvement in the clinical picture of the oral mucos
Exploring Xenobiotic Sensing in Implant Dentistry: A Literature Review
No full textImplant-supported rehabilitation is a well-supported evidence-based therapeutic strategy for replacing missing teeth in partially or completely edentulous patients, with predictable long-term success rates.(1) Dental implants are biomaterials used to regain lost chewing function and aesthetic in various edentulous cases. Dental implant materials are required to be non-allergic, sterilizable, biocompatible, and resistant to corrosion and occlusal loads(2). Different materials have been used in the fabrication of dental implants; however, commercially pure titanium (Ti) is still the material of choice in implant dentistry.(3) Titanium is a transition metal with a silver colour, known for high strength and resistance to corrosion. Its outstanding capacity to incorporate into bone is a phenomenon termed “osseointegration”.(4) Titanium has been considered a biological modulator of oral health. The ions and metal particles released may alter the interior physiological oral environment and initiate peri-implantitis or trigger a peri-implantitis flare(5). Nevertheless, concerns have been raised regarding titanium’s potential to induce hypersensitivity or inflammatory reactions in the host tissues which could lead to various complications in certain cases. It was reported that titanium ions may lead to systemic side effects such as hypersensitivity or allergy, and may disseminate to lymph nodes, liver and spleen in individuals with hip and knee prosthesis (6,7). The purpose of this review was to compile the current evidence regarding the association between the release of titanium particles from dental implants and its biologic complication
Systemic Medications and Their Impact on Dental Implant Osseointegration- A Review
No full textDental implants are a widely accepted treatment for rehabilitating partially or completely edentulous patients. However, implant failure remains a concern, especially in individuals on long-term pharmacological therapy. Evidence suggests that systemic medications such as NSAIDs, corticosteroids, bisphosphonates, SSRIs, PPIs, chemotherapeutic agents, and antihypertensives may impair osseointegration and peri-implant tissue health by affecting bone remodelling, angiogenesis, and immune responses. This review critically analyzes the impact of these drugs on implant outcomes, underlying mechanisms, and clinical evidence, while emphasizing risk assessment and management strategies to optimize implant success in medically compromised patients.
Introduction: Dental implants have significantly advanced prosthodontic rehabilitation by providing a reliable and esthetic solution for the replacement of missing teeth. The long-term success of implants depends on osseointegration, a biological process involving the direct structural and functional connection between the implant surface and alveolar bone. Although local factors such as bone quality, implant design, and surgical technique are well established, systemic conditions—particularly medication use—are increasingly recognized for their impact on implant prognosis. Several widely prescribed systemic drugs can influence bone metabolism, healing, and vascularization, thereby affecting osseointegration. Nonsteroidal anti-inflammatory drugs (NSAIDs) may delay bone healing by inhibiting prostaglandin synthesis, while corticosteroids can suppress bone formation and contribute to osteopenia [1]. Bisphosphonates, used in managing osteoporosis and metabolic bone disorders, inhibit osteoclastic activity and may compromise bone remodelling around implants [18,19]. Selective serotonin reuptake inhibitors (SSRIs) are linked to decreased bone mineral density, whereas proton pump inhibitors (PPIs) reduce calcium absorption and impair bone turnover [32,37]. Chemotherapeutic agents can hinder osteoblast function and angiogenesis, and prolonged antihypertensive therapy may alter bone remodelling through calcium and renal metabolism [50,59]. Recognizing these pharmacological effects is essential for identifying high-risk patients, optimizing treatment planning, and improving implant success rates.
Objectives: To evaluate how commonly prescribed systemic medications affect dental implant osseointegration and to highlight their clinical implications and strategies for optimizing implant success.
Conclusions: Systemic medications can significantly influence dental implant osseointegration by affecting bone metabolism, healing, and vascularization. Awareness of these drug–implant interactions enables clinicians to identify high-risk patients, tailor treatment planning, and implement strategies to enhance implant survival and achieve predictable long-term outcomes
Comparative evaluation of debris removal from root canal wall by using EndoVac and conventional needle irrigation: An in vitro study
No full textContext: Microbial control is of paramount importance in Clinical Endodontics. Therefore, cleaning and disinfection of root canals are essential to achieve endodontic success. Aims: The purpose of this study is to compare the efficacy of EndoVac irrigation system and conventional needle (30 gauges side venting needle) irrigation for removal of debris from the root canal walls at coronal, middle and apical third by using the scanning electron microscopy (SEM). Settings and Design: An in vitro randomized control trial study. Materials and Methods: A total of 20 mandibular premolars with completely formed roots were selected and randomly divided into two groups - Group 1: Irrigation with the Conventional system and Group 2: EndoVac irrigation. After access opening and working length determination biomechanical preparation completed up to a rotary protaper F4 file. Groupwise irrigation with sodium hypochlorite and ethylenediaminetetraacetic acid was done with each canal in between instrumentation. Then, the teeth were sectioned in buccolingual direction and the halves were sputter-coated with gold palladium and coronal, middle and apical third were examined by SEM at x2000 magnification. Statistical Analysis: Mann-Whitney test for comparison between methods, Kruskal-Wallis test for comparison among thirds and Miller test for individual comparisons. Results: The apical, middle and cervical root canal thirds were evaluated and the results were analyzed statistically by the Mann-Whitney test for comparison between methods, Kruskal-Wallis test for comparison among thirds and Miller test for individual comparisons. Conclusions: EndoVac group resulted in significantly less debris at apical third compared with the conventional needle irrigation group. There was no statistical significant difference found in debris removal at coronal and middle third of root canal wall between the EndoVac group and conventional needle irrigation group
Endodontic management of mandibular first molar with seven canals using cone-beam computed tomography
No full textThe endodontic treatment of a mandibular molar with aberrant canal configuration can be diagnostically and clinically challenging. Successful endodontic therapy thus depends on the clinician's ability to anticipate and look for these aberrant variations. A mandibular first molar with seven canals represents a rare anatomical variant, particularly when four canals are found in distal root. Based on in vitro studies, its incidence is reported to be between 0.2% and 3%. With the advent of cone-beam computed tomography (CBCT) as an adjunctive diagnostic aid, the determination of root canal anatomy in teeth with complex canal configurations has become more precise. The present case report discusses successful nonsurgical management of radix entomolaris along with middle mesial canal and middle distal canal in mandibular first molar with seven canals (four canals in distal and three in mesial) employing CBCT as an adjunctive diagnostic aid to conventional radiography
Stress analysis at bone-implant interface of single- and two-implant-retained mandibular overdenture using three-dimensional finite element analysis
No full textPurpose: The purpose of this research was to compare stress distribution on the bone between single implant-retained and two-implant-retained mandibular overdentures using three-dimensional (3D) finite element analysis.
Materials and Methods: Two 3D finite element models were designed. The first model included single implant-supported mandibular overdenture placed in the midline of the mandible while the second model included two-implant-supported mandibular overdenture placed in the intra-foramen region, retained by ball attachment of the same diameter. The bone was modeled on the D2 bone depending on the classification given by Misch. A computed tomography scan of the mandible was used to model the bone by plotting the key points on the graph and generating the identical key points on the ANSYS Software (ANSYS, Inc., USA). The implant was modeled using appropriate dimensions as provided by the manufacturer. Stresses were calculated based on the von Mises criteria.
Results: Stresses produced in the hard bone (HB) and soft bone (SB) were higher in single implant-retained mandibular overdenture while stresses produced around the denture as well as implant were higher in two-implant-retained mandibular overdenture.
Conclusion: Within the limitations of the study, it had been seen that stresses produced were the highest on HB and SB in single implant-retained mandibular overdenture while stresses produced across the denture as well as implant were the highest in two-implant-retained mandibular overdenture
Stress analysis at bone-implant interface of single- and two-implant-retained mandibular overdenture using three-dimensional finite element analysis
No full textFirst in the Nation in Education : Final Report,1984.
No full textThis report is one step in an ongoing process of change and is a plea for commitment for high standards in education in Iowa. Contains the final reports of the six subcommittees as adopted by the Excellence in Education Task Force, and the five recommendations made by the Task Force
“Kiss me with the hollow of your mouth” – imagining falling in love with Stense Andrea Lind-Valdan
No full textThe essay reflects upon the function of images within the love encounter, drawing on the personal experience of the author and his partner, visual artist Stense Andrea Lind-Valdan. Mixing personal experiences, diaristic notes and academic reflections, the essay moves beyond conventional scholarly style and experiments with more personal and anecdotal modalities, thus creating a text that re-enacts the fascination and imaginary entrapments involved in the love encounter while simultaneously reflecting upon these aspects of love
Comparative evaluation of the effect of three different attachment systems on stress distribution patterns in two implant supported maxillary overdenture: a 3d finite element analysis
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