314 research outputs found
The Post Office Horizon system and Seema Misra
No full textThe author highlights the significance of the Seema Misra case in raising questions about the reliablity of the Post Office Horizon system and more widely suggesting that all digital systems have the possibility of latent defects, and these can never be discounted. He argues that when the efficacy of digital systems is called into question in legal proceedings, the onus of proof must be placed on the supplier of these systems and not the accuser.Index words: Post Office; Horizon; prosecutions; software errors; disclosure Full transcript of the trial Regina v Seema Misra, T2009007 (England & Wales; theft; electronic evidence; Post Office Horizon System; ‘reliability’ of computers) with case commentary and index to original papers held in the Documents Supplement of Volume 12: 2015
Centralization of Decentralized Governance - Evidence from West Bengal Panchayat
No full textDemocratic decentralization in the state of West Bengal, of its own, are not producing systems that are more effective or more accountable to local needs and interests. The formal mechanisms matter less than the informal institutions that underpin local political economies. And the understanding of it by the poor may have been reflected in the ballot box of last Panchayat election held in 2008. If 'only alternative of the left is better left', then the left strategy of democratic decentralization must have to be replaced by alternative model with more accountability, less corruption and abolition of those clientilsm.Democratic decentralization, participation, access, control, sustainable development, clientelism
Centralization of Decentralized Governance - Evidence from West Bengal Panchayat
No full textDemocratic decentralization in the state of West Bengal, of its own, are not producing systems that are more effective or more accountable to local needs and interests. The formal mechanisms matter less than the informal institutions that underpin local political economies. And the understanding of it by the poor may have been reflected in the ballot box of last Panchayat election held in 2008. If 'only alternative of the left is better left', then the left strategy of democratic decentralization must have to be replaced by alternative model with more accountability, less corruption and abolition of those clientilsm
Erratum: Myocardial ischaemia and valve insufficiency caused by a dysplastic aortic valve cusp: A previously unreported unique morphologic anomaly (Cardiology in the Young (2020) (1-4) DOI: 10.1017/S1047951120001377)
No full text© The Author(s), 2020. The authors apologise that upon publication of this case report an author was left off. The online version of this article has been updated to list the authors correctly. Sharmeen Samuel, Preeta Dhanantwari, Nilanjana Misra, and David B. Meyer
Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase
No full textCitation: Ye, Z., Needham, P. G., Estabrooks, S. K., Whitaker, S. K., Garcia, B. L., Misra, S., . . . Camacho, C. J. (2017). Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase. Scientific Reports, 7(1). doi:10.1038/s41598-017-01880-4C-terminus of Hsc/p70-Interacting Protein (CHIP) is a homodimeric E3 ubiquitin ligase.Each CHIP monomer consists of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.In contrast to nearly all homodimeric proteins, CHIP is asymmetric.To uncover the origins of asymmetry, we performed molecular dynamics simulations of dimer assembly.We determined that a CHIP monomer is most stable when the HH domain has an extended helix that supports intra-monomer TPR-U-box interaction, blocking the E2-binding surface of the U-box.We also discovered that monomers first dimerize symmetrically through their HH domains, which then triggers U-box dimerization.This brings the extended helices into close proximity, including a repulsive stretch of positively charged residues.Unable to smoothly unwind, this conflict bends the helices until the helix of one protomer breaks to relieve the repulsion.The abrupt snapping of the helix forces the C-terminal residues of the other protomer to disrupt that protomer's TPR-U-box tight binding interface, swiftly exposing and activating one of the E2 binding sites.Mutagenesis and biochemical experiments confirm that C-terminal residues are necessary both to maintain CHIP stability and function.This novel mechanism indicates how a ubiquitin ligase maintains an inactive monomeric form that rapidly activates only after asymmetric assembly. © 2017 The Author(s)
Parallel session 9 : Institutional management
No full textPresented Titles: Living in Uncertainty: The COVID-19 Pandemic and Higher Education in Hong Kong [Authors: Jisun Jung; Hugo Horta; Gerard A. Postiglione] Internalisation of China’s Higher Education and It’s Development Model [Author: Rochester Lima] Unprepared Cost of Survival: Revisiting Academic Returnees’ Cross-border Capital and Cultural Adaptation in Shanghai Universities [Authors: Jiaxin Chen; Xiaoxin Du] Us and Them: How Regions Shape the Boundaries of Elite Higher Education? [Author: Debananda Misra
Towards Social Security Systems in Japan Lessons for India
No full textJapan has to restructure its social security systems fromtime to time for different reasons like a far more rapid aging of population , the slow down of long term economic growth and deteriorating equity in the inter-generational transfer of welfare .But even then, the basic elements remain the same .It si pertinent to see how and to whar extent japan’s social security systems could be translated in the case of India. As apreliminary analysis ,in section One, attempt has been made to summarize the distinctive features of social security systems in Japan.Section Two dwells upon the nature and problems of the social security systems in India. An endeavour has been made in Section three to articulate on the lessons for India. Final Section Four concludes and summarizes the main findings.It has ben observed that there are certain experiences that India can learn ,amongothers, the careful application of universal social security systems, the role of insurance policies,private-public synergies ,the role of the government and governance, the importance attached to social capital
Towards Social Security Systems in Japan Lessons for India
No full textJapan has to restructure its social security systems fromtime to time for different reasons like a far more rapid aging of population , the slow down of long term economic growth and deteriorating equity in the inter-generational transfer of welfare .But even then, the basic elements remain the same .It si pertinent to see how and to whar extent japan’s social security systems could be translated in the case of India. As apreliminary analysis ,in section One, attempt has been made to summarize the distinctive features of social security systems in Japan.Section Two dwells upon the nature and problems of the social security systems in India. An endeavour has been made in Section three to articulate on the lessons for India. Final Section Four concludes and summarizes the main findings.It has ben observed that there are certain experiences that India can learn ,amongothers, the careful application of universal social security systems, the role of insurance policies,private-public synergies ,the role of the government and governance, the importance attached to social capital.Universal social security system, private–public partnership, Inter-generational Equity governance, social capital
Supporting Cyber-Physical Systems with Wireless Sensor Networks: An Outlook of Software and Services
No full textSensing, communication, computation and control technologies are the essential building blocks of a cyber-physical system (CPS). Wireless sensor networks (WSNs) are a way to support CPS as they provide fine-grained spatial-temporal sensing, communication and computation at a low premium of cost and power. In this article, we explore the fundamental concepts guiding the design and implementation of WSNs. We report the latest developments in WSN software and services for meeting existing requirements and newer demands; particularly in the areas of: operating system, simulator and emulator, programming abstraction, virtualization, IP-based communication and security, time and location, and network monitoring and management. We also reflect on the ongoing
efforts in providing dependable assurances for WSN-driven CPS. Finally, we report on its applicability with a case-study on smart buildings
Mitigating industrial pollution in urban water bodies using African Sharptooth catfishes
No full textDepartment of Economics, Dhruba Chand Halder College, Dakshin Barasat-743 372, South 24-Parganas,
West Bengal, India
E-mail: [email protected]
Department of Microbiology, Asutosh College, Kolkata-700 026, India
Manuscript received online 29 January 2019, accepted 25 March 2019
Clarias gariepinus or African Sharptooth catfish survives in minimal amount of dissolved oxygen (DO) levels in stable water aquatic systems. Clarias gariepinus has a gill structure which can trap oversized pollutants molecules, hold them for long and excretes out for organic wastes. The main objective of the present study was to investigate the impacts on urban water pollution before and after the application of Clarias gariepinus in water bodies by measuring metal concentrations in water and sediment. Results shows that concentration of more than recommended level of Cr, Cu, Zn, Fe, Pb, Cd and Ni in urban water bodies can be reduced by recruiting Clarias gariepinus in those water bodies
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