31 research outputs found

    FFR pressure wire comparative study for drift: piezo resistive versus optical sensor

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    Background: This study aimed to assess the stability of pressure derived fractional flow reserve (FFR) measurement and the handling performance of the OptoWire Deux with an optical pressure sensor relative to the PressureWire X with piezo resistive pressure sensors. Methods: This multicenter centre observational study included 50 patients between June 2017 and November 2018 undergoing a diagnostic coronary angiography with FFR measurement of moderate to severe lesions. The reliability of FFR measurement measured with the OptoWire Deux relative to the PressureWire X in each lesion was assessed by the presence of drift. Handling characteristics for both pressure wires were assessed by a 5-point scale and by comparing the time between equalization and crossing the distal target lesion. Results: Hundred and sixteen measurements in 50 patients were performed. Very stable and reliable FFR measurements with the optical sensors were registered, relative to the piezo resistive pressure sensors. There is statistically significant difference in favor of the OptoWire Deux over the PressureWire X (P=0.001). However, the differences are small, when drift values were compared as continuous variables, no statistically significant difference was found for both directional (P=0.435) as for absolute drift (P=0.058). Conclusions: In patients undergoing FFR measurement, both optical sensor pressure wires (Optowire Deux) as piezo resistive sensor pressure wires (PressureWire X) generate stable and reliable pressure and thus FFR measurement. The optical pressure sensor is less susceptible for drift relative to the piezo resistive pressure sensor, but the difference is within an acceptable range.We would like to thank Jo Zelis and Marcel van ‘t Veer from the Department of Biomedical Engineering of the University of Technology Eindhoven for his statistical support

    Wages and unemployment in Poland : recent developments and policy issues

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    The authors review recent developments in wages, employment, and unemployment in Poland and discuss some of the main risks Poland faces in sustaining its stabilization effort. They find that: unemployment has increased dramatically with stabilization, but this increase cannot be said to reflect widespread economic adjustment and restructuring throughout the Polish economy; and wages showed a significant degree of downward flexibility - in real terms - at the beginning of the year, when firms faced a severe supply shock coupled with very tight credit. The wage policy still in force in Poland at the end of 1991 maintains a few undesirable features. The monthly indexation and the possibility of carrying forward the unused margins are among the policy's main drawbacks; another is the link between wages and profitability. The current wage policy could be replaced by a generalized agreement on the wage path, with synchronized six-month contracts. The wage path should be related to expected inflation and economywide productivity. This scheme would also have the advantage of being based on a consensual agreement instead of being perceived as being imposed as a punitive tax.Youth and Governance,Banks&Banking Reform,Economic Theory&Research,Health Monitoring&Evaluation,Environmental Economics&Policies

    Final results of the randomised evaluation of short-term dual antiplatelet therapy in patients with acute coronary syndrome treated with a new-generation stent (REDUCE trial)

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    Aims: The optimal duration of DAPT in ACS patients treated with DES is still unclear. Therefore, the aim of the current study was to investigate a short versus a standard 12-month DAPT regimen in ACS patients undergoing new-generation DES implantation.Methods and results: REDUCE was a prospective, open-label, multicentre, investigator-initiated study that randomised 1,496 ACS patients after treatment with the COMBO stent to either three (n=751) or 12 months (n=745) of DAPT. The primary study endpoint was a composite of all-cause mortality, myocardial infarction, stent thrombosis, stroke, target vessel revascularisation and bleeding at 12 months. No difference was observed in the demographic and clinical characteristics between the two groups, except for gender (p=0.01). At one-year follow-up, non-inferiority of three-versus 12-month DAPT in the primary endpoint was met (8.2% vs 8.4%, p(non-inferiority)Conclusions: The results show that, among ACS patients treated with the COMBO stent, three months is non-inferior to 12 months of DAPT. However, given the numerically higher rates of mortality and ST in the three-month DAPT group, one-year DAPT should still be recommended in ACS until more information becomes available. A three-month DAPT strategy should be considered only if clinically mandated.</p

    Problemy definicyjne w nauczaniu i badaniu khmerskiej grzeczności językowej

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    The author of this article refers to a set of vital definitions one has to take into consideration in teaching and reserarching language politeness. Etnolinguistic analyze of language savoir vivre is impossible vithout reference to key anthrolological notions such as culture, cultural pattern, education. The basis used in this article to reconcile various antrophological schools is the theory of Geert Hofstede who proposes wide and simple definition of culture, treated as a “‘collectively programmed mind” that differs one group or category of people from other. Being a Khmer naturalized in Polad, the author is fucused on pupularization of Khmer language and culture in her second motherland. Having a sense of mission to provide Polish users of Khmer language with cultural competence that will anable them to be seen in Cambodia as polite people, the author compares Polish and Khmer colloquial understanding of politeness. She also refers to Polish linguistic works on language politeness, looking for definitional solutions that will help teach and analyze language savoir vivre of the KhmersThe author of this article refers to a set of vital definitions one has to take into consideration in teaching and reserarching language politeness. Etnolinguistic analyze of language savoir vivre is impossible vithout reference to key anthrolological notions such as culture, cultural pattern, education. The basis used in this article to reconcile various antrophological schools is the theory of Geert Hofstede who proposes wide and simple definition of culture, treated as a “‘collectively programmed mind” that differs one group or category of people from other. Being a Khmer naturalized in Polad, the author is fucused on pupularization of Khmer language and culture in her second motherland. Having a sense of mission to provide Polish users of Khmer language with cultural competence that will anable them to be seen in Cambodia as polite people, the author compares Polish and Khmer colloquial understanding of politeness. She also refers to Polish linguistic works on language politeness, looking for definitional solutions that will help teach and analyze language savoir vivre of the Khmer
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