5 research outputs found
ENTERIC OPPORTUNISTIC PARASITIC INFECTIONS IN HIV SEROPOSITIVE PATIENTS AT TERTIARY CARE TEACHING HOSPITAL
No full textBackground: Enteric opportunistic parasitic infections are the major source of diarrheal disease in developing countries mainly in Human Immunodeficiency virus (HIV) infected patients.
Objective: The study was to detect enteric parasites causing diarrhea and their association with immune status in HIV-seropositive patients.
Methods: The present study was conducted in tertiary care teaching Hospital, Baroda between January 2006 to January 2007 involving 100 Human Immunodeficiency virus (HIV) seropositive patients.From all patients stool samples collected and stool was examined for enteric parasites by microscopy with special staining methods.
Results: A total of 100 HIV sero-positive patients with and without diarrhea were included in the study. Of the 100 patients, the protozoan parasitic infection was found in 28% (28/100). Out of 100 patients, 50 had diarrhea in which parasitic infection was 24 (48%) and 4 (4/50) protozoal parasites positive cases did not have diarrhea. A significant difference (p<0.05) was observed in the level of infection of intestinal protozoan between the HIV seropositive with diarrhea and HIV-seropositive without diarrhea.
Conclusion: Enteric opportunistic parasitic infections were detected in 28% among HIV-seropositive patients. Early detection of enteric parasitic infections will help in the management and to improve the quality of life for HIV-infected individuals
Long-COVID versus adverse event following COVID vaccination among students and staff of tertiary care teaching hospital
No full textBackground: Long COVID is an important public health concern requiring proper defining, quantifying and describing following SARS-CoV infection with differentiation from adverse events due to COVID vaccination. So, this study was planned to analyze adverse effect of COVID19 vaccination or drug for COVID treatment versus consequences of COVID19 infection.
Methods: Self-reported data was collected through questionnaire-based survey by voluntary participation of healthcare staff. Percentage of participant developing various events was analyzed by enlisting sign, symptom, co-morbidity and medication history. Association between COVID-19 infection with number of doses of COVID-19 vaccine taken was analyzed by Chi Square Test with p value <0.05. Association between presence of specific sign, symptom after COVID infection or side effect after COVID vaccination was analyzed by Chi-Square Test with p value <0.05.
Results: Overall total 985 (59.58%) participants were analyzed and among them maximum number of participants (60.30%) reported as COVID-19 positive during the third wave with history of diagnosed COVID positive twice (57.87%). Participants with presence of co-morbidity were more likely to develop symptoms (p<0.001). On analysis, fever, body ache, headache, sore throat and fatigue were significantly more likely to develop after COVID infection as compared to after COVID vaccination (p<0.001).
Conclusions: This study by exploratory survey highlights heterogeneity of Long COVID sign or symptom that’s seen predominantly in person with co-morbidity and a few of them were mimicking adverse events after COVID vaccinations
To Study the Causative Organism Responsible for Corneal Ulcer In S.S.G Hospital Vadodara, Gujarat
No full textIntroduction: Number of blind people in the world is 45 million. Out of which 5.4 million blind people are in our country. Corneal ulcer is a major cause of blindness throughout the world. About 10% cases of blindness are due to corneal ulcer.
Aims: To detect bacteria or fungus causing corneal ulcers and to give rapid presumptive diagnosis from direct smear examination.
Study Design: 150 samples were collected during period of 1 year from clinically diagnosed cases of corneal ulcer at SSG Hospital, Baroda. The patients were of both sex and age groups varying from 2 to 70 years, outpatient department as well as indoor patients
Study Period: one and half years
Results: A total number of 150 patients presenting with suppurative keratitis were enrolled in the study from Ophthalmology department, SSG Hospital & Medical College, Baroda. Of the total 150 patients 99 (66%) were males & 51 (44%) were females with ulceration occurs in both group most frequently in the middle decades of life
A STUDY ON VENTILATOR ASSOCIATED PNEUMONIA IN PEDIATRIC AGE GROUP IN A TERTIARY CARE HOSPITAL, VADODARA
No full textIntroduction: Approximately 10-28% of critical care patients develop Ventilator Associated Pneumonia (VAP). It increases length of stay in ICU up to 28% and each incidence ofVentilator-associated pneumonia(VAP) is estimated to generate an increased cost of £6000-£22000. Mortality rate is 24%-71%.
Objectives: To determine the incidence rate, bacteriological profile and antibiotic sensitivity pattern of ventilator-associated pneumonia in pediatric intensive care unit (PICU) & Neonatal intensive care unit(NICU)
Methods: In this study total 125 patients of pediatric age group admitted in ICU & put on ventilator at SSGH from November 2010 to November 2011 were enrolled. After the clinical confirmation according to CDC criteria, the endotracheal secretion were collected and processed as per standard microbiological methods and antibiotic sensitivity pattrn of each were recorded.
Results: Of total 125 samples 58 samples were positive. Most common Organism isolated are Klebseilla spp.(35%), Acinetobactor spp.(26%), Psedomonas spp.(15%),other enterobactriacae(13%), Gram positive cocci(8%) and candida spp(3%). Among the isolates for Gram Negative Bacilli – Imipenem and Vancomycin for Gram Positive Cocci is recommended.
Conclusion: Among the isolates for Gram Negative Bacilli – Imipenem and Vancomycin for Gram Positive Cocci is recommende
A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer
No full text© The Author 2015. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Funding This work was supported the National Institutes of Health (R01CA092039 05/05S1) and the National Institute of Dental and Craniofacial Research (1R03DE020116). Notes The authors thank all of the participants who took part in this research and the funders and technical staff who made this study possible. We acknowledge and thank Simone Benhamou (INSERM, France) for sample contributions. We also acknowledge and thank The Cancer Genome Atlas initiative, whose data contributed heavily to this study.Peer reviewe
