1,489 research outputs found
Estimating Causal Effects of Early Occupational Choice on Later Health: Evidence Using the PSID
No full textIn this paper, we provide some of the first empirical evidence of whether early occupational choices are associated with lasting effects on health status, affecting individuals as they age. We take advantage of data on occupational histories available in the Panel Study of Income Dynamics (PSID) to examine this issue. To the PSID data, we merge historical Census data that reflect the labor market conditions when each individual in the PSID made his first occupational choice. These data on labor market conditions (e.g. state-level share of blue collar workers) allow us to instrument for occupational choice in order to alleviate endogeneity bias. We use parental occupation as additional instruments. Since our instruments may have indirect effects on later health, we also control for respondent’s pre-labor market health, education and several family and state background characteristics in order to make the instruments more plausibly excludable. We find substantial evidence that a blue collar occupation at labor force entry is associated with decrements to later health status, ceteris paribus. These health effects are larger after controlling for endogeneity and are similar across sets of instruments. We also find differences in the effects of occupation by gender, race, and age.
Earthquake and tsunami impact analysis of five Oregon coastal communities
No full textReport -- Spreadsheet.by John M. Bauer, Jonathan C. Allan, Laura L. S. Gabel, Fletcher E. O'Brien, and Jed T. Roberts.Title from PDF cover (viewed on July 7, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Child Mental Health and Human Capital Accumulation: The Case of ADHD Revisited
No full textRecently, Currie and Stabile (2006) made a significant contribution to our understanding of the influence of ADHD symptoms on a variety of school outcomes including participation in special education, grade repetition and test scores. Their contributions include using a broad sample of children and estimating sibling fixed effects models to control for unobserved family effects. In this paper we look at a sample of older children and confirm and extend many of the JCMS findings in terms of a broader set of measures of human capital and additional specifications.
Earthquake and tsunami impact analysis for coastal Tillamook County, Oregon
No full textby Jonathan C. Allan, Fletcher E. O'Brien, John M. Bauer, and Matthew C. Williams.Title from PDF cover (viewed on December 24, 2020)."This report evaluates a Cascadia subduction zone earthquake (Mw 9.0) and tsunami (M1, L1, and XXL1 scenarios) affecting coastal Tillamook County, Oregon, in order to understand the degree of potential destruction, including building losses, debris generated, fatalities and injuries, and estimated numbers of the displaced populations. The goal is to help coastal communities prepare for this inevitable disaster"--Page ii.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 62-68).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Earthquake and tsunami impact analysis for coastal Clatsop County, Oregon
No full textby Jonathan C. Allan, Fletcher E. O'Brien, John M. Bauer, and Matthew C. Williams.Title from PDF cover (viewed on January 21, 2021).Covers OCLC #1232236431 and OCLC #1202421190."This report evaluates a Cascadia subduction zone earthquake (Mw 9.0) and tsunami (M1, L1, and XXL1 scenarios) affecting coastal Clatsop County, Oregon, in order to understand the degree of potential destruction, including building losses, debris generated, fatalities and injuries, and estimated numbers of the displaced populations. The goal is to help coastal communities prepare for this inevitable disaster"--Page ii.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 57-63).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Cumulative Effects of Job Characteristics on Health
No full textWe examine whether the job characteristics of physical demands and environmental conditions affect individual’s health. Five-year cumulative measures of these job characteristics are used to reflect findings in the biologic and physiologic literature that indicate that cumulative exposure to hazards and stresses harms health. To create our analytic sample, we merge job characteristics from the Dictionary of Occupational Titles with the Panel Study of Income Dynamics dataset. We control for early and lagged health measures and a set of pre-determined characteristics to address concerns that individuals self-select into jobs. Our results indicate that individuals who work in jobs with the ‘worst’ conditions experience declines in their health, though this effect varies by demographic group. For example, for non-white men, a one standard deviation increase in cumulative physical demands decreases health by an amount that offsets an increase of two years of schooling or four years of aging. We also find evidence that job characteristics are more detrimental to the health of females and older workers. Finally, we report suggestive evidence that earned income, another job characteristic, partially cushions the health impact of physical demands and harsh environmental conditions for workers. These results are robust to inclusion of occupation fixed effects.
Seawater carbonate chemistry and performance of native and non-native adult oysters
No full textGlobally, non-native species (NNS) have been introduced and now often entirely replace native species in captive aquaculture; in part, a result of a perceived greater resilience of NSS to climate change and disease. Here, the effects of ocean acidification and warming on metabolic rate, feeding rate, and somatic growth was assessed using two co-occurring species of oysters – the introduced Pacific oyster Magallana gigas (formerly Crassostrea gigas), and native flat oyster Ostrea edulis. Biological responses to increased temperature and pCO2 combinations were tested, the effects differing between species. Metabolic rates and energetic demands of both species were increased by warming but not by elevated pCO2. While acidification and warming did not affect the clearance rate of O. edulis, M. gigas displayed a 40% decrease at ∼750 ppm pCO2. Similarly, the condition index of O. edulis was unaffected, but that of M. gigas was negatively impacted by warming, likely due to increased energetic demands that were not compensated for by increased feeding. These findings suggest differing stress from anthropogenic CO2 emissions between species and contrary to expectations, this was higher in introduced M. gigas than in the native O. edulis. If these laboratory findings hold true for populations in the wild, then continued CO2 emissions can be expected to adversely affect the functioning and structure of M. gigas populations with significant ecological and economic repercussions, especially for aquaculture. Our findings strengthen arguments in favour of investment in O. edulis restoration in UK waters
Generating high-performance FPGA accelerator designs for big data analytics with Fletcher and Apache Arrow
No full textAs big data analytics systems are squeezing out the last bits of performance of CPUs and GPUs, the next near-term and widely available alternative industry is considering for higher performance in the data center and cloud is the FPGA accelerator. We discuss several challenges a developer has to face when designing and integrating FPGA accelerators for big data analytics pipelines. On the software side, we observe complex run-time systems, hardware-unfriendly in-memory layouts of data sets, and (de)serialization overhead. On the hardware side, we observe a relative lack of platform-agnostic open-source tooling, a high design effort for data structure-specific interfaces, and a high design effort for infrastructure. The open source Fletcher framework addresses these challenges. It is built on top of Apache Arrow, which provides a common, hardware-friendly in-memory format to allow zero-copy communication of large tabular data, preventing (de)serialization overhead. Fletcher adds FPGA accelerators to the list of over eleven supported software languages. To deal with the hardware challenges, we present Arrow-specific components, providing easy-to-use, high-performance interfaces to accelerated kernels. The components are combined based on a generic architecture that is specialized according to the application through an extensive infrastructure generation framework that is presented in this article. All generated hardware is vendor-agnostic, and software drivers add a platform-agnostic layer, allowing users to create portable implementations.Computer Engineerin
The telomere binding protein TRF2 induces chromatin compaction.
No full textMammalian telomeres are specialized chromatin structures that require the telomere binding protein, TRF2, for maintaining chromosome stability. In addition to its ability to modulate DNA repair activities, TRF2 also has direct effects on DNA structure and topology. Given that mammalian telomeric chromatin includes nucleosomes, we investigated the effect of this protein on chromatin structure. TRF2 bound to reconstituted telomeric nucleosomal fibers through both its basic N-terminus and its C-terminal DNA binding domain. Analytical agarose gel electrophoresis (AAGE) studies showed that TRF2 promoted the folding of nucleosomal arrays into more compact structures by neutralizing negative surface charge. A construct containing the N-terminal and TRFH domains together altered the charge and radius of nucleosomal arrays similarly to full-length TRF2 suggesting that TRF2-driven changes in global chromatin structure were largely due to these regions. However, the most compact chromatin structures were induced by the isolated basic N-terminal region, as judged by both AAGE and atomic force microscopy. Although the N-terminal region condensed nucleosomal array fibers, the TRFH domain, known to alter DNA topology, was required for stimulation of a strand invasion-like reaction with nucleosomal arrays. Optimal strand invasion also required the C-terminal DNA binding domain. Furthermore, the reaction was not stimulated on linear histone-free DNA. Our data suggest that nucleosomal chromatin has the ability to facilitate this activity of TRF2 which is thought to be involved in stabilizing looped telomere structures
Gender-specific Pathways of Peer Influence on Adolescent Suicidal Behaviors
No full text The author explores new directions of understanding the pathways of peer influence on adolescent suicidal behavior by leveraging quasi-experimental variation in exposure to peer suicidal behaviors and tracing the flows of influence throughout school environments and networks. The author uses variation in peers’ family members’ suicide attempts to deploy an across–grade level, within-school analysis to estimate causal effects. Key findings include a gender-specific pathway, whereby girls are affected by their female grademates’ experiences with family member suicidality but are unaffected by their male grademates. These specific pathways allow novel approaches to be used that leverage the gender specificity of the influences within an instrumental variable analysis. The findings suggest large (gender-specific) peer effects on suicidal behaviors in adolescence. </jats:p
- …
