100,439 research outputs found
Dynamic design matter[s]: Practical considerations for interactive architecture
No full textThis paper explores the concept of interactive architecture. The first section begins by formulating a daring vision of a radically new kind of architecture. In the second chapter this vision is further elaborated upon, by proposing a generic approach towards practically accomplishing the originally formulated theoretical concept. Opportunities and threats that emerge from this vision and approach are discussed in the third section and eventually, in section four and five, the proposed approach is brought to practical applications and illustrated with a number of experimental building component examples that all together include all necessary features to create a complete large scale architectural object. All projects and explorations have been conducted as part of the Hyperbody groups research at the Delft University of Technology and have been inspired by groups director, prof. Kas OosterhuisArchitectur
Process-driven architecture: Design techniques and methods
No full textThis paper explores the notion of process-driven architecture and, as a consequence, application of complex systems in the newly defined area of digital process-driven architectural design in order to formulate a suitable design method. Protospace software environment and SwarmCAD software application are introduced and physical, real scale prototypes of architectural installations illustrate the new approach to creating architecture.Architectur
'iPortals' as a case study pre-prototype of an evolving network of interactive spatial components
No full textThe art and craft of desiesign and creation of buildings is undergoing a radical paradigm shift. This shift is being driven by diverse novel cross-disciplinary technical possibilities, as well as by ongoing cultural transformations. They all, directly or indirectly, originate from omnipresent advancements in information technologies. Instant and ubiquitous availability of information and immediate access to computing power pervasively penetrating our lives is profoundly transforming our culture. This phenomenon has enormous implications for architecture in a multitude of ways.Firstly, the speed of changes that occur in modern-day culture and society makes it inconvenient or even entirely impossible to design buildings with fixed and permanent functionalities. As lifestyle patterns, production methods and environmental conditions, to name a few factors only, may now dramatically change from one day to another, architecture has to become flexible. It has to allow dynamic, active, or even pro-active adaptation and customization of spaces on many levels of its functionality 2.Secondly, these profound cultural changes are not only of technical relevance. In its process-driven character, information technology strongly mandates the already widely recognized ontology of becoming, proclaimed by the prominent minds of contemporary philosophy and science. This process-oriented worldview, supported by latest technological possibilities3, has caused a radical change in the common sense of the manner in which architecture has to be understood and dealt with4. As an effect, it requires an in-depth reconsideration of the nature of processes of both creation and participation in spatial environments.Architectur
Towards a Methodology for Complex Adaptive Interactive Architecture
No full textArchitectural Engineering + TechnologyArchitectur
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
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