931 research outputs found
[photograph] Portret van Jan Cools en Michiel Hendryckx.
No full textFotoarchief Michiel HendryckxFoto rechts beschadigdHet digitaal beeld dat u bij deze foto ziet, werd na digitalisering bewerkt door Michiel Hendryckx zelf. De analoge foto kan afwijken van dit digitaal beeld.De foto kan u fysiek raadplegen in de leeszaal. Een scan opvragen is op vraag van de fotograaf niet mogelijk.Hendryckx, MichielHendryckx, MichielBijzondere collectiesJan Cools (kunstschilder) (l) en Michiel Hendryckx (fotograaf) (r
sj-docx-1-cpj-10.1177_00099228231191924 – Supplemental material for The Use of Standardized Solutions Instead of Individualized Prescriptions for Parenteral Nutrition on the Neonatal Intensive Care Unit in UZ Brussel: A Feasibility Study
No full textSupplemental material, sj-docx-1-cpj-10.1177_00099228231191924 for The Use of Standardized Solutions Instead of Individualized Prescriptions for Parenteral Nutrition on the Neonatal Intensive Care Unit in UZ Brussel: A Feasibility Study by Melanie Batteux, Garmt Meers, Bockstal Fien, Pieter-Jan Cortoos and Filip Cools in Clinical Pediatrics</p
Large Time Step and DC Stable TD-EFIE Discretized with Implicit Runge-Kutta Methods
No full textThe time domain-electric field integral equation (TD-EFIE) and its differentiated version are widely used to simulate the transient scattering of a time dependent electromagnetic field by a perfect electric conductor (PEC). The time discretization of the TD-EFIE can be achieved by a space-time Galerkin approach or, as it is considered in this contribution, by a convolution quadrature using implicit Runge-Kutta methods. The solution is then computed using the marching-on-in-time (MOT) algorithm. The differentiated TD-EFIE has two problems: 1) the system matrix suffers from ill-conditioning when the time step increases (low frequency breakdown) and 2) it suffers from the DC instability, i.e., the formulation allows for the existence of spurious solenoidal currents that grow slowly in the solution. In this article, we show that 1) and 2) can be alleviated by leveraging quasi-Helmholtz projectors to separate the Helmholtz components of the induced current and rescale them independently. The efficacy of the approach is demonstrated by numerical examples including benchmarks and real-life applications.Numerical Analysi
New flow cytometry in hematologic malignancies
No full textThe complex and heterogeneous biology of acute lymphoblastic leukemia is unfolding as more experimental approaches such as expression profiling, DNA sequencing, and high resolution genomic arrays continue to unveil new recurrent alterations. In this perspective article, Drs. Cools and Vandenberghe examine new diagnostic applications of flow cytometry. See related paper on page 1767.status: Publishe
Eminentissimi [...] Josephi Saenz de Aguirre [...] Disputationes selectæ de multorum Belgarum præcipue Lovaniensium Jansenismo in genere et specie /
No full textProbably printed in Ghent by Jan DanckaertKopij-impr.: Juxta ecemplar impressum Coloniæ Agrippinæ : apud Wilhelmum FriessemEpistola pastoralis [...] super præcipuis ecclesiæ Belgicæ turbis; per jll.mum et r.mum dom. Reginaldum Cools Ruræmundensem episcopum / Humbertus Guilielmus a Præcipiano. -- Quæstio curiosa an Alexander papa VII. et Belgii episcopi in famosa formula exigant, ut juretur in aliquid quod spectat ad quæstionem. - - Joannis Wicleff hæresiarchæ Anglicani, & Joannis Husz Bohemi ejus sequacis articuli, à Constantiensi generali concilio [...] damnati.Herkomst: Bibliotheca DominicanaEuropeana-GoogleBook
Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia
No full textOver the past 20 years, a large number of genes involved in the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) has been identified by molecular characterization of recurrent chromosomal aberrations and more subtle genetic defects. When reviewing the current list of oncogenes and tumor suppressor genes, it becomes clear that these can be grouped into four classes of mutations, which are involved in: (i) cell cycle deregulation; (ii) impaired differentiation; (iii) proliferation and survival advantage and (iv) unlimited self-renewal capacity. Based on recent studies of T-ALL, we can speculate that at least these four different mutations are required for the development of T-ALL. In this review we summarize our current insights into the molecular pathogenesis of T-ALL, and we discuss how these molecular findings provide new directions for future research and novel therapeutic strategies in T-ALL.sponsorship: Kim De Keersmaecker is an Aspirant, and Jan Cools is a Postdoctoral Researcher of the FWO-Vlaanderen. Our work is supported by grants from the FWO-Vlaanderen, the Belgian Federation against Cancer (BFK), and the European Hematology Association (EHA) (Jose-Carreras Fellowship grant to J.C.). (FWO-Vlaanderen, Belgian Federation against Cancer (BFK), European Hematology Association (EHA) (Jose-Carreras Fellowship grant))status: Publishe
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