1,720,980 research outputs found
Ensemble Machine Learning and Its Validation for Prediction of Coronary Artery Disease and Acute Coronary Syndrome Using Focused Carotid Ultrasound
No full textThe objective of this study is to demonstrate the effectiveness of ensemble-learning-driven machine learning (EML) algorithms over the conventional ML (CML) algorithms in predicting cardiovascular events (CVEs) such as coronary artery disease (CAD) and acute coronary syndrome (ACS). Furthermore, this study demonstrates the improvement in overall CVE prediction by including carotid ultrasound image phenotypes in the feature set. The methodology consisted of collecting and amalgamating 24 risk predictors along with coronary angiography as the gold standard. We further hypothesize that for such a fused set of predictors, EML systems can perform better compared with CML systems. The EML system design consisted of risk predictors for each of 459 participants undergoing baseline characteristics and independent K10-based training model generation based on three sets of algorithms: seven CML, three homogeneous ensemble ML (EML-homo), and five heterogeneous ensemble ML (EML-hetro). These training models were then applied to the test patients to predict CAD and ACS. As part of the performance, the AUC for EML-homo improved over CML by 4.3% for CAD and 1.1% for ACS, respectively. Similarly, the AUC for EML-hetro improved over CML by 3.23% for CAD and 2.11% for ACS, respectively. The proposed EML-based system was validated against the two validation databases consisting of 303 and 522 participants for CAD and ACS. We thus conclude that the EML-based algorithms are better in predicting CAD and ACS, compared with CML, proving our hypothesis
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Cardiovascular/stroke risk prevention: A new machine learning framework integrating carotid ultrasound image-based phenotypes and its harmonics with conventional risk factors
No full textMotivation: Machine learning (ML)-based stroke risk stratification systems have typically focused on conventional risk factors (CRF) (AtheroRisk-conventional). Besides CRF, carotid ultrasound image phenotypes (CUSIP) have shown to be powerful phenotypes risk stratification. This is the first ML study of its kind that integrates CUSIP and CRF for risk stratification (AtheroRisk-integrated) and compares against AtheroRisk-conventional. Methods: Two types of ML-based setups called (i) AtheroRisk-integrated and (ii) AtheroRisk-conventional were developed using random forest (RF) classifiers. AtheroRisk-conventional uses a feature set of 13 CRF such as age, gender, hemoglobin A1c, fasting blood sugar, low-density lipoprotein, and high-density lipoprotein (HDL) cholesterol, total cholesterol (TC), a ratio of TC and HDL, hypertension, smoking, family history, triglyceride, and ultrasound-based carotid plaque score. AtheroRisk-integrated system uses the feature set of 38 features with a combination of 13 CRF and 25 CUSIP features (6 types of current CUSIP, 6 types of 10-year CUSIP, 12 types of quadratic CUSIP (harmonics), and age-adjusted grayscale median). Logistic regression approach was used to select the significant features on which the RF classifier was trained. The performance of both ML systems was evaluated by area-under-the-curve (AUC) statistics computed using a leave-one-out cross-validation protocol. Results: Left and right common carotid arteries of 202 Japanese patients were retrospectively examined to obtain 404 ultrasound scans. RF classifier showed higher improvement in AUC (~57%) for leave-one-out cross-validation protocol. Using RF classifier, AUC statistics for AtheroRisk-integrated system was higher (AUC = 0.99,p-value<0.001) compared to AtheroRisk-conventional (AUC = 0.63,p-value<0.001). Conclusion: The AtheroRisk-integrated ML system outperforms the AtheroRisk-conventional ML system using RF classifier
A machine learning framework for risk prediction of multi-label cardiovascular events based on focused carotid plaque B-Mode ultrasound: A Canadian study
No full textMotivation: Machine learning (ML) algorithms can provide better cardiovascular event (CVE) prediction. However, ML algorithms are mostly explored for predicting a single CVE at a time. The objective of this study is to design and develop an ML-based system to predict multi-label CVEs, such as (i) coronary artery disease, (ii) acute coronary syndrome, and (iii) a composite CVE—a class of AtheroEdge 3.0 (ML) system. Methods: Focused carotid B-mode ultrasound and coronary angiography are performed on a group of 459 participants consisting of three cardiovascular labels. Initially, 23 risk predictors comprising (i) patients’ demographics, (ii) clinical blood-biomarkers, and (iii) carotid ultrasound image-based phenotypes are collected. Six types of classification techniques comprising (a) four problem transformation methods (PTM) and (b) two algorithm adaptation methods (AAM) are used for multi-label CVE prediction. The performance of the proposed system is evaluated for accuracy, sensitivity, specificity, F1-score, and area-under-the-curve (AUC) using 10-fold cross-validation. The proposed system is also verified using another database of 522 participants. Results: For the primary database, PTM demonstrated a better multi-label CVE prediction than AAM (mean accuracy: 80.89% vs. 62.83%, mean AUC: 0.89 vs. 0.63), validating our hypothesis. The PTM-based binary relevance (BR) technique provided optimal performance in multi-label CVE prediction. The overall multi-label classification accuracy, sensitivity, specificity, F1-score, and AUC using BR are 81.2 ± 3.01%, 76.5 ± 8.8%, 83.8 ± 3.8%, 75.37 ± 5.8%, and 0.89 ± 0.02 (p < 0.0001), respectively. When used on the second Canadian database with seven cardiovascular events (acute coronary syndrome, myocardial infarction, angina, stroke, transient ischemic attack, heart failure, and death), the proposed system showed an accuracy of 96.36 ± 0.87% (AUC: 0.61 ± 0.06, p < 0.0001). Conclusion: ML-based multi-label classification algorithms, such as binary relevance, yielded the best predictions for three cardiovascular endpoints
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
- …
