1,720,953 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Evaluation of different media for implementation of dissolution testing of a matrix tablet on an apparatus simulating the movement of human intestine
Full text linkPreskus sproščanja peroralnih farmacevtskih oblik se običajno izvaja bodisi za namene kontrole kakovosti, kjer preverjamo skladnost izdelka, bodisi za namene raziskav in razvoja, kjer si želimo poustvariti čim bolj biorelevantno okolje, ki nam omogoča visoko stopnjo in vitro-in vivo korelacije. V ta namen se poslužujemo uporabe kompleksnih in vitro modelov in metod, s katerimi lahko dosegamo visoko in vivo napovedno moč. Glavni cilj magistrske naloge je bil opredeliti uporabnost novega in vitro modela, razvitega v podjetju Lek d.d. Ljubljana, ki posnema črevesno gibanje, za sproščanje trdnih peroralnih farmacevtskih oblik v črevesu. S tem namenom smo preskusili sproščanje učinkovine iz treh formulacij hidrofilnih ogrodnih tablet z različnimi kinetikami sproščanja (hitra, srednje hitra, počasna formulacija) in iz referenčnega zdravila. Pri ogrodni tableti je učinkovina porazdeljena v ogrodju, ki nam, v primerjavi z oblikami s takojšnjim učinkom, omogoča nadzorovano sproščanje skozi daljše časovno obdobje. Ovrednotili smo pet različnih metod za izvedbo preskusa sproščanja. V acetatnem pufru pH-4,5 (program P03), kjer smo preverjali vpliv pH na sproščanje učinkovine, je le-to potekalo hitreje kot pri drugi primerljivi metodi (fosfatni pufer pH-6,8, program P04) zaradi večje topnosti oziroma hitrosti raztapljanja modelne učinkovine. V umetnem črevesnem soku, ki posnema pogoje na tešče (FaSSIF), smo dosegli najmanjša razlikovanja med formulacijami z različnimi kinetikami sproščanja in najmanjše ujemanje z in vivo opaženo kinetiko (razmerja med deleži sproščene učinkovine iz testnih formulacij in reference). Dodatek NaCl fosfatnemu pufru oziroma povišanje ionske jakosti je zaradi izsoljevanja upočasnilo sproščanje učinkovine v primerjavi s pufrom brez dodatka NaCl. Pri vseh preskušenih medijih oziroma metodah smo z modelom uspeli doseči razlikovanja med formulacijami z različnimi kinetikami sproščanja. Kot najboljša za izbrano formulacijo se je izkazala metoda s kalijevim fosfatnim pufrom pH-6,8 in programom P12, saj smo na ta način dosegli največje ujemanje z in vivo opaženo kinetiko. Prav tako smo z metodo dosegli boljše ujemanje z in vivo razmerji kot s klasično napravo z vesli (USP II). S predstavljenim primerom želimo prikazati uporabnost in fleksibilnost naprave oziroma novega in vitro modela, za katerega pričakujemo, da bo lahko uspešno simuliral sproščanje tudi drugih podobnih formulacij.Dissolution testing of oral dosage forms is usually performed either for quality control purposes testing the compliance of batches or for research and development purposes simulating a biorelevant environment that allows high degree of in vitro-in vivo correlation. For this purpose we use complex in vitro models and methods that reach a high level of in vivo prediction. The main objective of this master’s thesis has been to assess the efficacy of a new in vitro model developed at Lek d.d. Ljubljana simulating the movement of human intestine for evaluation of dissolution of oral dosage forms in human intestine. Therefore, we performed dissolution testing of three different hydrophilic matrix tablets with different release kinetics (fast, medium and slow release) and a reference product. In a matrix tablet the active ingredient is distributed in the matrix allowing for a controlled release over a longer time period compared to an immediate release form. We evaluated five different methods for dissolution testing. Acetate buffer pH-4,5 (program P03) where we examined the influence of pH on the release of the active ingredient showed a faster release rate in comparison to the other equivalent method (phosphate buffer pH-6,8, program P04) due to its higher solubility in acidic environment. Fasted state simulated intestinal fluid showed the least discrimination between formulations with different release rates as well as the greatest discrepancy to in vivo observed kinetics (test formulations/reference ratios from in vivo study). Due to salting out, addition of NaCl to phosphate buffer (increase in ionic strength) reduced release rates as compared to a buffer without addition of NaCl. The model was able to show discrimination between formulations with different release kinetics in all tested media. Owing to the greatest correlation with in vivo observed kinetics the method with phosphate buffer pH-6,8 and program P12 was established as the best formulation. Compared to the conventional USP II paddle method, the aforementioned method showed better correlation to observed in vivo ratios. The presented case aims to show efficacy and flexibility of the method and the novel in vitro model which is expected to successfully simulate dissolution of other similar formulations
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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