1,279 research outputs found

    Higher Hida theory and p-adic L-functions for GSp(4)

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    We use the "higher Hida theory" recently introduced by the second author to p-adically interpolate periods of non-holomorphic automorphic forms for GSp(4), contributing to coherent cohomology of Siegel threefolds in positive degrees. We apply this new method to construct p-adic L-functions associated to the degree 4 (spin) L-function of automorphic representations of GSp(4), and the degree 8 L-function of GSp(4) x GL(2)

    Episode of The Lawmakers on powerful members of the U.S. House of Representatives out of the public eye

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    Television news program The Lawmakers on powerful members of the U.S. House of Representatives not often in the public eye. Replays stories on Jamie L. Whitten and Silvio Conte from a 1981 episode

    Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus \u2014 Duke University, Durham, North Carolina, August 2\u2013October 11, 2020

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    What is already known about this topic? SARS-CoV-2 can rapidly spread through university settings. Pooling specimens can enable large-scale tTesting while minimizing needed resources.What is added by this report? In fall 2020, Duke University\u2019s COVID-19 Prevention strategy included risk reduction behaviors, frequent tTesting using pooled SARS-CoV-2 polymerase chain reaction tTesting, and contact tracing. Among 10,265 students who received tTesting 68,913 times, 84 had positive results. One half of infections were asymptomatic, and some had high viral loads.What are the implications for public health practice? SARS-CoV-2 Transmission was limited in this congregate setting by integration of Prevention strategies that included identification of asymptomatic infections through frequent tTesting. Pooled tTesting reduced the need for resources while allowing high throughput with high sensitivity and rapid turnaround of results.On university campuses and in similar congregate environments, Surveillance tTesting of asymptomatic persons is a critical strategy (1,2) for preventing Transmission of SARS-CoV-2, the Virus that causes coronaVirus disease 2019 (COVID-19). All students at Duke University, a private research university in Durham, North Carolina, signed the Duke Compact (3), agreeing to observe mandatory masking, social distancing, and participation in entry and Surveillance tTesting. The university implemented a five-to-one pooled tTesting program for SARS-CoV-2 using a quantitative, in-house, laboratory-developed, real-time reverse transcription\u2013polymerase chain reaction (RT-PCR) test (4,5). Pooling of specimens to enable large-scale tTesting while minimizing use of reagents was pioneered during the human immunodeficiency Virus pandemic (6). A similar methodology was adapted for Duke University\u2019s asymptomatic tTesting program. The baseline SARS-CoV-2 tTesting plan was to distribute tests geospatially and temporally across on- and off-campus student populations. By September 20, 2020, asymptomatic tTesting was scaled up to tTesting targets, which include tTesting for residential undergraduates twice weekly, off-campus undergraduates one to two times per week, and graduate students approximately once weekly. In addition, in response to newly identified positive test results, tTesting was focused in locations or within cohorts where data suggested an increased risk for Transmission. Scale-up over 4 weeks entailed redeploying staff members to prepare 15 campus tTesting sites for specimen collection, developing information management tools, and repurposing laboratory automation to establish an asymptomatic Surveillance system. During August 2\u2013October 11, 68,913 specimens from 10,265 graduate and undergraduate students were tested. Eighty-four specimens were positive for SARS-CoV-2, and 51% were among persons with no symptoms. Testing as a result of contact tracing identified 27.4% of infections. A combination of risk-reduction strategies and frequent Surveillance tTesting likely contributed to a prolonged period of low Transmission on campus. These findings highlight the importance of combined tTesting and contact tracing strategies beyond symptomatic tTesting, in association with other preventive measures. Pooled tTesting balances resource availability with supply-chain disruptions, high throughput with high sensitivity, and rapid turnaround with an acceptable workload.Suggested citation for this article: Denny TN, Andrews L, Bonsignori M, et al. Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus \u2014 Duke University, Durham, North Carolina, August 2\u2013October 11, 2020. MMWR Morb Mortal Wkly Rep. ePub: 17 November 2020.mm6946e1.htm?s_cid=mm6946e1_wmm6946e1-H.pd

    The construction of Karen Karnak: The multi-author-function

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    This thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author

    Codes, Cultures, Chaos, and Champions: Common Features of Legal Codification Experiences in China, Europe, and North America

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    What are the key conditions and factors that contribute to a successful effort within a political unit to create a new legal code? This article builds of the existing "comparative codification" literature by examining that question in the context of three very different legal traditions: dynastic Chinese law, European civil law, and North American common law. Drawing on nine important codification experiences-four from China, two from Europe and three from North American-the author posits that three conditions must exist in a legal system for codification to occur: (i) that written law is generally regarded favorably as a means of ordering society; (ii) that the top political authority in the society is powerful enough to impose a code; and (iii) that such top political authority is eager to champion the cause of codification. Assuming these three necessary conditions are present, several key contributing factors-for example, cultural change and legal chaos-further augur in favor of codification. The author identifies five such factors and illustrates their importance in each of the nine codification experiences. The article concludes with some observations about (i) the value of including traditional Chinese law in comparative codification studies and (ii) the interplay between the concentration of political power (lacking, for example, in the international legal system) and the likelihood of legal codification

    An Archival Case Study : Revisiting the Life and Political Economy of Lauchlin Currie

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    This paper forms part of a wider project to show the significance of archival material on distinguished economists, in this case Lauchlin Currie (1902-93), who studied and taught at Harvard before entering government service at the US Treasury and Federal Reserve Board as the intellectual leader of Roosevelt's New Deal, 1934-39, as FDR's White House economic adviser in peace and war, 1939-45, and as a post-war development economist. It discusses the uses made of the written and oral material available when the author was writing his intellectual biography of Currie (Duke University Press 1990) while Currie was still alive, and the significance of the material that has come to light after Currie's death

    A CO2 Monitoring and Control System for Plant Growth Chambers

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    Author Institution: Botany Department and Phytotron, Duke UniversityPATTERSON, DAVID T. AND JOHN L. HITE. A CO2 monitoring and control system for plant growth chambers. Ohio J. Sci. 75(4): 190, 1975

    Trusted Tales: Creating Authenticity in Literary Representations from Ex-Yugoslavia

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    This research deals with questions of authority and authenticity and how they are expressed, constructed, and appropriated within the Anglophone book market. It considers the body of literature written about ex-Yugoslavia since the 1990s Balkan conflicts by exiled writers from the region which has entered the international literary canon. Books’ routes from original publishers into English translation are discussed through practices of trust, one of the crucial social devices underpinning their exchange. Within these cross-cultural processes, the role of cultural brokers is crucial. Symbolic and cultural resources are specifically mobilised through their powerful author brands. By exploring authenticity in the context of book publishing, I further look at how ideas and practices of community are employed and negotiated by writers and those who promote their books. My field is multi-sited and fluid, reflecting how different individual and national positions are enacted and performed through strategies ranging from unconscious dispositions to deliberate intentions. This research thus brings together ideas of the author as an authentic, representative voice together with exile as a position that grants them a new lease of relevancy in the post-socialist context. Although ex-Yugoslav books occupy a ‘high end’ niche of the UK market, constrained by commercial as well as political, cultural, and institutional forces, in public discourse ideas of the ‘free market’ and ‘free speech’ are mobilised to produce various types of modernisation narratives. The (post)socialist production of literature is perceived as having to ‘evolve’ into a capitalist model: this would allow not only healthy competition and consumer choice but guarantee an individual writer ‘free speech’ as a basic human right. Therefore, the most general question this research raises is what kind of foreign literature gets translated into English, under what socio-cultural conditions and which politics of representation it serves within the project of world literature

    Implementation of a Pooled Surveillance Testing Program for Asymptomatic SARS-CoV-2 Infections on a College Campus - Duke University, Durham, North Carolina, August 2-October 11, 2020.

    No full text
    On university campuses and in similar congregate environments, surveillance testing of asymptomatic persons is a critical strategy (1,2) for preventing transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19). All students at Duke University, a private research university in Durham, North Carolina, signed the Duke Compact (3), agreeing to observe mandatory masking, social distancing, and participation in entry and surveillance testing. The university implemented a five-to-one pooled testing program for SARS-CoV-2 using a quantitative, in-house, laboratory-developed, real-time reverse transcription-polymerase chain reaction (RT-PCR) test (4,5). Pooling of specimens to enable large-scale testing while minimizing use of reagents was pioneered during the human immunodeficiency virus pandemic (6). A similar methodology was adapted for Duke University's asymptomatic testing program. The baseline SARS-CoV-2 testing plan was to distribute tests geospatially and temporally across on- and off-campus student populations. By September 20, 2020, asymptomatic testing was scaled up to testing targets, which include testing for residential undergraduates twice weekly, off-campus undergraduates one to two times per week, and graduate students approximately once weekly. In addition, in response to newly identified positive test results, testing was focused in locations or within cohorts where data suggested an increased risk for transmission. Scale-up over 4 weeks entailed redeploying staff members to prepare 15 campus testing sites for specimen collection, developing information management tools, and repurposing laboratory automation to establish an asymptomatic surveillance system. During August 2-October 11, 68,913 specimens from 10,265 graduate and undergraduate students were tested. Eighty-four specimens were positive for SARS-CoV-2, and 51% were among persons with no symptoms. Testing as a result of contact tracing identified 27.4% of infections. A combination of risk-reduction strategies and frequent surveillance testing likely contributed to a prolonged period of low transmission on campus. These findings highlight the importance of combined testing and contact tracing strategies beyond symptomatic testing, in association with other preventive measures. Pooled testing balances resource availability with supply-chain disruptions, high throughput with high sensitivity, and rapid turnaround with an acceptable workload

    #MeToo: Why Now? What Next?

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    Deborah L. Rhode, the Ernest W. McFarland Professor of Law at Stanford University, delivers the Brainerd Currie Memorial and Kenan Institute for Ethics Distinguished Lecture, #MeToo: Why Now? What Next? . Prof. Rhode, director of Stanford\u27s Center on the Legal Profession and Program in Law and Social Entrepreneurship, is the most frequently cited scholar on legal ethics and the author or co-author of over 30 books in the area of professional responsibility, leadership, and gender. She has received the American Bar Association\u27s Michael Franck Award for contributions to the field of professional responsibility and Pro Bono Publico Award for her work on expanding public service opportunities in law schools, the American Bar Foundation\u27s W. M. Keck Foundation Award for distinguished scholarship on legal ethics and Outstanding Scholar Award, and the White House\u27s Champion of Change Award for a lifetime\u27s work in increasing access to justice. Sponsored by the Office of the Dean and the Kenan Institute for Ethics
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