1,584 research outputs found
[Notice of change of name of a law firm, Prappas, Moncure, Harris & Termini, June 1, 1977]
No full textNotice announcing a change in the partners and therefore firm name from Prappas, Caldwell & Moncure to Prappas, Moncure, Harris & Termini. The members of the law firm are listed as: Dempsey J. Prappas, John L. Moncure, Brantly Harris, James T. Termini, Jack E. Eidman, Jr., Sweeney J. Doehring, Jr., Terrance P. Baggott, B. Edward Williamson, Thomas D. Solomon, and Michael R. Carr
TIME EVOLUTION OF LOCAL SCOURING DOWNSTREAM OF A RIGID BED:lessons learned from experiments
No full textThis present work concerns the phenomenon of local erosion occurring downstream a rigid bed of a structure constructed along a river. In particular, attention is focused on the time evolution of the maximum scour depth. This chapter reports a brief review of findings obtained by author using both data appositely collected in a laboratory channel and literature data
Termini
No full textThe video piece ‘Termini’ captures a fleeting moment in public space: the movement of swallows in flight over the piazza behind the Statzione Termini in Rome. The physical location where the video is shot periodically infiltrates the visual frame of the image as a digitally lit text naming the terminating station on the bus route. This infiltration creates a tear in the temporal progress of the moving image, disrupting and arresting the progress of the mutating mass of swallows flying overhead. The resulting single-channel video and audio work directly compares the light, delicate and mesmerising motion of the birds in flight with the more mundane, banal and human systems of bus routes, terminals and travel plans
On FUZZINESS vol 1
No full textThe notion of Fuzziness stands as one of the really new concepts that have recently enriched the world of Science. Science grows not only through technical and formal advances on one side and useful applications on the other side, but also as consequence of the introduction and assimilation of new concepts in its corpus. These, in turn, produce new developments and applications. And this is what Fuzziness, one of the few new concepts arisen in the XX Century, has been doing so far.
This book aims at paying homage to Professor Lotfi A. Zadeh, the “father of fuzzy logic” and also at giving credit to his exceptional work and personality. In a way, this is reflected in the variety of contributions collected in the book. In some of them the authors chose to speak of personal meetings with Lotfi; in others, they discussed how certain papers of Zadeh were able to open for them a new research horizon. Some contributions documented results obtained from the author/s after taking inspiration from a particular idea of Zadeh, thus implicitly acknowledging him.
Finally, there are contributions of several “third generation fuzzysists or softies” who were firstly led into the world of Fuzziness by a disciple of Lotfi Zadeh, who, following his example, took care of opening for them a new road in science
Hydrogen Bonding is the Prime Determinant of Carboxyl pKa Values at N-termini of Alpha-Helices
No full textExperimentally determined mean pKa values of carboxyl residues located at N-termini of alpha-helices are lower than their overall mean values. Here, we perform three types of analyses to account for this phenomenon. We estimate the magnitude of the helix macrodipole to determine its potential role in lowering carboxyl pKa values at N-termini. No correlation between the magnitude of the macro-dipole and the pKa values is observed. Using the pKa program propKa we compare the molecular surroundings of 18 N-termini carboxyl residues versus 233 protein carboxyl groups from a previously studied database. While pKa lowering interactions at N-termini are similar in nature to those encountered in other protein regions, pKa lowering backbone and sidechain hydrogen bonds appear in greater number at N-termini For both Asp and Glu, there are about 0.5 more hydrogen bonds per residue at N-termini than in other protein regions which can be used to explain their lower than average pKa values. Using a QM-based pKa prediction model, we investigate the chemical environment of the two lowest Asp and the two lowest Glu pKa values at N-termini so as to quantify the effect of various pKa determinants. We show that local interactions suffice to account for the acidity of carboxyl residues at N-termini. The effect of the helix dipole on carboxyl pKa values, if any, is marginal. Backbone amide hydrogen bonds constitute the single biggest contributor to the lowest carboxyl pKa values at N-termini. Their estimated pKa lowering effects range from about 1.0 to 1.9 pKa units
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Mapping proteolytic neo-N termini at the surface of living cells
No full textN terminomics is a powerful strategy for profiling proteolytic neo-N termini, but its application to cell surface proteolysis has been limited by the low relative abundance of plasma membrane proteins. Here we apply plasma membrane-targeted subtiligase variants (subtiligase-TM) to efficiently and specifically capture cell surface N termini in live cells. Using this approach, we sequenced 807 cell surface N termini and quantified changes in their abundance in response to stimuli that induce proteolytic remodeling of the cell surface proteome. To facilitate exploration of our datasets, we developed a web-accessible Atlas of Subtiligase-Captured Extracellular N Termini (ASCENT; http://wellslab.org/ascent). This technology will facilitate greater understanding of extracellular protease biology and reveal neo-N termini biomarkers and targets in disease
A geophysical study of the termini of the Mount Cook National Park glaciers
No full textDespite much work on the shape of valley glaciers, little is known about the shape of their termini (the lower end of a glacier). A geophysical investigation was carried out on the termini of the Tasman, Murchison, Mueller and Hooker Glaciers to determine the shape of the termini and to determine whether any ice existed under the outwash gravels.
Using the gravity and resistivity techniques it was found that glacial ice ended at the terminus of each glacier, none extending out under the outwash gravels. The Murchison Glacier was found to be 230 m (± 50 m) thick 2 - 3 km upstream from the terminus. The Tasman Glacier was found to be 600 m (± 90 m) thick 10 km upstream from the terminus thinning to 200 m 2 km from the terminus. The Hooker Glacier has a thickness of 150 m 1.5 km upstream from the terminus.
Overall melting (ablation) of the termini of these glaciers is continuing, mainly by basal melting. Continued ablation of the terminus of the Tasman Glacier will result in the formation of one large melt-lake within the next 10 - 20 years (i.e. by 1990)Examination Versio
Motivated proteins: a web application for studying small three-dimensional protein motifs
No full text<b>BACKGROUND:</b> Small loop-shaped motifs are common constituents of the three-dimensional structure of proteins. Typically they comprise between three and seven amino acid residues, and are defined by a combination of dihedral angles and hydrogen bonding partners. The most abundant of these are alphabeta-motifs, asx-motifs, asx-turns, beta-bulges, beta-bulge loops, beta-turns, nests, niches, Schellmann loops, ST-motifs, ST-staples and ST-turns.We have constructed a database of such motifs from a range of high-quality protein structures and built a web application as a visual interface to this. <b>DESCRIPTION:</b> The web application, Motivated Proteins, provides access to these 12 motifs (with 48 sub-categories) in a database of over 400 representative proteins. Queries can be made for specific categories or sub-categories of motif, motifs in the vicinity of ligands, motifs which include part of an enzyme active site, overlapping motifs, or motifs which include a particular amino acid sequence. Individual proteins can be specified, or, where appropriate, motifs for all proteins listed. The results of queries are presented in textual form as an (X)HTML table, and may be saved as parsable plain text or XML. Motifs can be viewed and manipulated either individually or in the context of the protein in the Jmol applet structural viewer. Cartoons of the motifs imposed on a linear representation of protein secondary structure are also provided. Summary information for the motifs is available, as are histograms of amino acid distribution, and graphs of dihedral angles at individual positions in the motifs. <b>CONCLUSION:</b> Motivated Proteins is a publicly and freely accessible web application that enables protein scientists to study small three-dimensional motifs without requiring knowledge of either Structured Query Language or the underlying database schem
MAPPING GLACIER TERMINI IN SOUTHERN ALASKA, 1931–1964
No full text A program to map changes in the positions of glacier termini in the coastal mountains of southern Alaska was initiated by the author in 1931, and since 1941 has been sponsored by the American Geographical Society. Wherever possible, stations previously used for surveys or photography were reoccupied, including a few established as early as the 1880's. After nine field trips, 50 triangulation networks have been established to cover 76 different termini of large and small glaciers, of which 26 are tidal. Photographs were taken from the principal stations to record changes in the topography and vegetation cover. The principal glaciers of Glacier Bay in southeastern Alaska and of Prince William Sound in southcentral Alaska have been surveyed five times.The surveys, supported by the photographic record, have documented pronounced advances of 8 termini and appreciable recession of 37; the remaining glaciers have either oscillated or remained virtually unchanged. The reason for the program, the instrumentation and procedures, and the field problems encountered are discussed, and recommendations are made for the future. </jats:p
"The Sisters" di James Joyce: strategie linguistiche e narrative.
No full textAll'interno di "The Sisters", racconto introduttivo di Gente di Dublino (1914) di James Joyce, si è riconosciuta una strategia narrativa ambigua, che si colloca a metà strada fra realismo e simbolismo. L'attenzione alle tecniche narrative interne si accompagna ad una focalizzazione di alcuni termini chiave (paralysis, simony, gnomon) della short story, che pongono le basi (culturali, antropologiche) della lettura di tutti i rimanenti quattordici racconti di Gente di Dublino
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