112 research outputs found
THE PREDISSOCIATION DYNAMICS OF COMPLEXES
No full text M.-C. Yang, A.P. Salzberg, B.-C. Chang, C.C. Carter and T.A. Miller, J. Chem. Phys. 98, 4301 (1993).Author Institution: Laser Spectroscopy Facility, The Ohio State UniversityIn some complexes (Rg = Ar and Kr), the natural lifetime of the state has remarkably lengthened compared with uncomplexed SH ( ns for the level). We have the natural lifetime of v, to levels of to be 600, 543, 405, 158 and 49 ns where the absolute value of the vibrational quantum number v. has not yet been determined. In , the natural lifetimes of different vibrational levels of the state do not vary dramatically. All the measurements indicate the natural lifetime of the state is about 600 ns. However, the natural lifetime of all observed bands are shorter than our instrumental limit (20ns). The details of the analysis and its physical interpretation will be discussed
Barbed Sutures in Breast Reconstruction
No full textPostoperative closure techniques in breast reconstruction have remained largely unchanged over the past 75 years, despite recent use of adhesives and subcuticular staples and the advent of self-anchoring barbed sutures. In this article, the author discusses the applications for barbed sutures in breast reconstruction and describes specific techniques. Innovations in barbed suture material are also described, and the author\u27s personal experiences are presented in comparison with traditional suturing techniques
When the Whole World Tips: The Buddhist Teaching of Equanimity for Parents
No full textParents witnessing suffering in their children activate the shared pain circuitry of empathy which may lead to “empathetic distress” (Singer & Klimecki, 2014, p. 875) precipitating hopelessness and despair. These common emotions in parents dealing with children’s illness or injury are the greatest predictors of depression (Abramson, Seligman, & Teasdale, 1978; Gilbert, 1992; Wilner & Goldstein, 2001). The author offers the Buddhist teachings of equanimity as an antidote to parental helplessness and despair. Equanimity engages compassion which activates the neural network of affiliation, love, reward, and positive affect (Anālayo, 2015; Desbordes et al., 2015; Feldman, 2017; Hanh, 1998; Klimecki, Leiberg, Lamm, & Singer, 2012; Kilmecki, Leiber, Ricard, & Singer, 2013; Olendzki, 2010; Rothberg, 2010; Salzberg, 1995; Singer & Klimenki, 2014). The components of equanimity include compassion, wisdom, and unfailing love (Anālayo, 2015; Desbordes et al., 2015; Feldman, 2017; Hanh, 1998; Olendzki, 2010; Rothberg, 2010; Salzberg, 1995). The addition of compassion, the intention to actively relieve suffering, helps maintain emotional sovereignty and protects from the common occurrence of burnout due to despair and hopelessness (Desbordes et al., 2015; Feldman, 2017; Hanh, 1998; Klimecki, Leiberg, Lamm, & Singer, 2012; Kilmecki, Leiber, Ricard, & Singer, 2013; Olendzki, 2010; Romm, 2007; Singer & Klimenki, 2014). This ancient Buddhist practice supports the restoration of intention and desire to effect change and offers a radically different approach to caring for both child and parent
Genome sequence of the pattern forming <it>Paenibacillus vortex </it>bacterium reveals potential for thriving in complex environments
No full textAbstract Background The pattern-forming bacterium Paenibacillus vortex is notable for its advanced social behavior, which is reflected in development of colonies with highly intricate architectures. Prior to this study, only two other Paenibacillus species (Paenibacillus sp. JDR-2 and Paenibacillus larvae) have been sequenced. However, no genomic data is available on the Paenibacillus species with pattern-forming and complex social motility. Here we report the de novo genome sequence of this Gram-positive, soil-dwelling, sporulating bacterium. Results The complete P. vortex genome was sequenced by a hybrid approach using 454 Life Sciences and Illumina, achieving a total of 289× coverage, with 99.8% sequence identity between the two methods. The sequencing results were validated using a custom designed Agilent microarray expression chip which represented the coding and the non-coding regions. Analysis of the P. vortex genome revealed 6,437 open reading frames (ORFs) and 73 non-coding RNA genes. Comparative genomic analysis with 500 complete bacterial genomes revealed exceptionally high number of two-component system (TCS) genes, transcription factors (TFs), transport and defense related genes. Additionally, we have identified genes involved in the production of antimicrobial compounds and extracellular degrading enzymes. Conclusions These findings suggest that P. vortex has advanced faculties to perceive and react to a wide range of signaling molecules and environmental conditions, which could be associated with its ability to reconfigure and replicate complex colony architectures. Additionally, P. vortex is likely to serve as a rich source of genes important for agricultural, medical and industrial applications and it has the potential to advance the study of social microbiology within Gram-positive bacteria.</p
Lernen individuell fördern – wie kann das gelingen?
No full textSchulisches Lernen gelingt nicht immer allen Kindern und Jugendlichen so gut, wie sie und auch die Lehrkräfte und Eltern es sich wünschten. Diese Kinder benötigen besondere Aufmerksamkeit und Unterstützung. Neben einer kontinuierlichen Beobachtung und Analyse ihres Lernverhaltens ist es hilfreich, schnell und flexibel bei der Planung von Fördermaßnahmen zu reagieren. Doch wie kann das in dem regulären Schulalltag gelingen?
Dieser Frage widmet sich der vorliegende Beitrag. Auf der Grundlage einer systematischen Analyse von Förderplänen und -maßnahmen und einer kurzen Beschreibung gelingender Lernhandlungen wird das in Brandenburger Schulen bereits erfolgreich eingesetzte Struktur-Lege-Verfahren zur individuellen Diagnostik und Förderplanung anhand eines Fallbeispiels vorgestellt.Some children and adolescents struggle with meeting the expectations they face when learning in the classroom. These learners need special attention and support. On the one hand, it is important to carefully observe and analyze their learning behavior. On the other hand, professional educators need to be able to react fast and flexibly to adjust their individual support plan.
This article presents and discusses an approach to guiding these planning processes by a structured collaborative procedure that uses a visualization technique. First, the author provides a systematic overview of different effective support strategies and presents a taxonomy for successful learning behaviors. Subsequently, the structured procedure for collaboratively planning diagnostics and support for learners is presented and illustrated in a case example
Identification and stage-specific association with the translational apparatus of TbZFP3, a CCCH protein that promotes trypanosome life-cycle development
No full textThe post-transcriptional control of gene expression is becoming increasingly important in the understanding of regulated events in eukaryotic cells. The parasitic kinetoplastids have a unique reliance on such processes, because their genome is organized into polycistronic transcription units in which adjacent genes are not coordinately regulated. Indeed, the number of RNA-binding proteins predicted to be encoded in the genome of kinetoplastids is unusually large, invoking the presence of unique RNA regulators dedicated to gene expression in these evolutionarily ancient organisms. Here, we report that a small CCCH zinc finger protein, TbZFP3, enhances development between life-cycle stages in Trypanosoma brucei. Moreover, we demonstrate that this protein interacts both with the translational machinery and with other small CCCH proteins previously implicated in trypanosome developmental control. Antibodies to this protein also co-immunoprecipitate EP procyclin mRNA and encode the major surface antigen of insect forms of T. brucei. Strikingly, although TbZFP3 is constitutively expressed, it exhibits developmentally regulated association with polyribosomes, and mutational analysis demonstrates that this association is essential for the expression of phenotype. TbZFP3 is therefore a novel regulator of developmental events in kinetoplastids that acts at the level of the post-transcriptional control of gene expression
Genome sequence of Lactobacillus amylovorus GRL1112
No full textLactobacillus amylovorus is a common member of the normal gastrointestinal tract (GIT) microbiota in pigs. Here, we report the genome sequence of L. amylovorus GRL1112, a porcine feces isolate displaying strong adherence to the pig intestinal epithelial cells. The strain is of interest, as it is a potential probiotic bacteriu
Genome sequence of Lactobacillus amylovorus GRL1118, isolated from pig ileum
No full textLactobacillus amylovorus is a common member of the beneficial microbiota present in the pig gastrointestinal tract. Here, we report the genome sequence of the surface layer (S-layer) protein-carrying and potentially probiotic strain L. amylovorus GRL1118, which was isolated from porcine ileum and which shows strong adherence to pig intestinal epithelial cell
16GT: A fast and sensitive variant caller using a 16-genotype probabilistic model
No full text© The Author 2017. Published by Oxford University Press. 16GT is a variant caller for Illumina whole-genome and whole-exome sequencing data. It uses a new 16-genotype probabilistic model to unify single nucleotide polymorphism and insertion and deletion calling in a single variant calling algorithm. In benchmark comparisons with 5 other widely used variant callers on a modern 36-core server, 16GT demonstrated improved sensitivity in calling single nucleotide polymorphisms, and it provided comparable sensitivity and accuracy for calling insertions and deletions as compared to the GATK HaplotypeCaller. 16GT is available at https://github.com/aquaskyline/16GT.published_or_final_versio
Rabbi Baruch Shapiro giving first blessing at wedding of Irving "Schick" Feinberg and Frieda Frei, Talmud Torah building, Seattle, January 9, 1949
No full textHandwritten on verso: Wedding of Schick Feinberg and Frieda Frei, Jan. 9, 1949 in Talmud Torah bldg. at 25th & Columbia. Rabbi Baruch Shapiro of Congregation Machzikay Hadath is giving the first blessing.
Note from donor file: Irving "Schick" Feinberg. Rabbi Baruch Shapiro, with tall hat, is giving the first of the seven blessings given to each married couple on the first 7 days after their wedding.
At table (L to R): Frieda's sister, Mali Sneiders, Frieda's father, Jacob Frei, bride and groom, Rabbi Shapiro, Isadore Schreiber, Isadore Rogoway, Harry Zak. 2nd row: Jake Feinberg, Dena Bayliss, Esther Rogoway, Roberta Lederman, Hilary Fisher, Salzberg child. Mrs. Gladstein, lady with glasses, behind Esther Rogoway. Bridesmaid with headdress, Harriet Furman, man with carnation Gene Rickles, next to him Rita Rickles, Phil Gladstein holding cup with striped necktie, tall boy behind Rabbi Shapiro might be Sigmund Fisher; girl at Rabbi Shapiro's right in profile is Minnie Shapiro; man with glasses behind her is Al Winters; on his right tall man at very back is Henry Schain, a pharmacist; man with hat at Schain's right Robert Wenkert; girl at very rear by door might be Ethel Alger. These people, most of them belong to Machzikay Hadath Congregation.
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