3 research outputs found
Effectiveness Comparison Between Young Leaf Extracts Acacia nilotica with Desmanthus virgatus Against Vermicidal Potency of Haemonchus contortus In-vitro
Acacia nillotica and Desmanthus virgatus are two entopharmacologycal plants that thrives throughout the season in East Nusa Tenggara Province, other Provinces in Indonesia or tropical countries. Extraction of young leaves of Acacia nillotica (EDMAN) and Desmanthus virgatus (EDMDV) contains tannin compound. By pharmacodynamic viewpoint, this extraction has potency as an anthelmintic. Objective: to compare the in-vitro effectivity of young leaves extraction of the two plants as a vermicidal power to combat Haemonchus contortus. Materials: young leaves of Acacia nillotica and Desmanthus virgatus and Haemonchus contortus. Method: The study was grouped into four treatments: EDMAN, EDMDV, Positive control (Albendazole 0,055%) and negative control (aquades). The concentration of the young leaves extracts are 2.5%, 3.5%, 4.5% out of 0.01 g/mL of extraction. Each treatment was applied to 6 female Haemonchus contortus with four replicates allowing immersion time for 1, 3, 5 or 7 hours. Variable measured and tested was mortality of the H. contortus. The vermicidal effectively was descriptively analysed. The results showed that mortality percentage (vermicidal) treatment of 2.5%, 3.5%, 4.5% EDMAN for 7-hour immersion was 16.7%, 45.8%, 12.5%, respectively. That values for EDMDV for similar concentrations and immersion time was 50%, 33.3%, 12.5%, respectively. Conclusion: EDMDV has a more effective vermicidal power between the two etnopharmacological treatments at 2.5% concentration
UJI KARAKTERISTIK SEDIAAN SALEP EKSTRAK ETANOL BUAH MAKASAR (Brucea javanica [L.] Merr) SEBAGAI KANDIDAT SALEP UNTUK LUKA INCISI DAN LUKA DIABETES
Makasar fruit (Brucea javanica [L]. Merr) has been widely used as herbal medicine to treat various types of diseases through simple processing. However, the use of Makasar fruit drugs with topical application as an ointment to treat incision wounds or diabetic wounds is extremely rare. The purpose of this research is to produce ointment and to assess the physical quality of the ointment made from the ethanolic extract of the Makassar fruit. The ointment used in this study was made with ethanol extract of Makassar fruit, alpha tocopherol, propyl-paraben, and Vaseline album. The data were observed descriptively and using a qualitative method. This study used two ointment concentrations, 15% and 20%, which were tested three times for each physical evaluation (organoleptic test, homogeneity test, dispersibility test, and pH test). The results showed that the ethanol extract of Makassar fruit could be formulated as an ointment, and the physical evaluation of the ointment discovered that the ointment met the organoleptic standards and the homogeneity standards. Furthermore, the pH test revealed that the ointment was safe to use; however, only 1 sample (repeat 1 concentration of 20%) confirmed that it did not meet the pH requirements because it was lower than the standard (acid pH). Furthermore, the dispersion tests indicated that the ointment did not meet the ointments dispersion standard. Conclusion: because the physical examination showed that the ointment met the standard values, the ointment can be made from the ethanol extract of Makassar fruit. However, because the ointment's spreadability is below the standard value, it must be taken into account.</jats:p
Anatomical and Histological Features of the Tongue Wild Boar (Sus scrofa) from Timor Island
The tongue is a complementary organ owned by living things that easily moves and fills the oral cavity when the upper and lower jaw teeth meet. This study aims to determine the anatomical structure and histology of the tongue in wild boar (Sus scrofa) from the Island of Timor. Tongue organs were collected from three healthy wild boars. Animals were slaughtered and necropsied. Macroscopic observations were made; length, width, and thickness were measured, and the tongue tissue was cut into several parts, namely the apex lingua, corpus lingua, and radix lingua, to be fixed in 10% formalin. Furthermore, Hematoxylin-Eosin (HE) staining was performed. The results showed that the dorsal surface has four types of papillae, namely circumvallate papillae, conical papillae, foliate papillae, fungiform papillae, and filiform papillae. The tongue muscles of wild boar were found to be m. longitudinalis, m. transversus, and m. verticalis. Conical papillae are conical with a blunt tip. Foliate papillae are located on the lateral-radix of the tongue. Fungiform papillae have a dome-like oval shape. Filiform papillae have an elongated cylindrical shape with a blunt tip. The size of the filiform papillae at the corpus of the tongue is larger than at the apex of the tongue.
