1,721,059 research outputs found
Molecular resolution visualization of a pore formed by trichogin, an antimicrobial peptide, in a phospholipid matrix
No full textElectrochemical scanning tunneling microscopy (EC-STM) was employed to study the aggregation of trichogin OMe
(TCG), an antimicrobial peptide, incorporated into a lipid monolayer. High-resolution EC-STM images show that
trichogin molecules aggregate to form channels in the lipid monolayer. Two types of aggregates were observed in
the images. The first consisted of a bundle of six TCGmolecules surrounding a central pore. The structure and dimensions
of this channel are similar to aggregates that in bilayers are described by the barrel-stave model. The EC-STM
images also reveal that channels aggregate further to form a hexagonal lattice of a two dimensional (2D) nanocrystal.
The model of 2D lattice was built from trimers of TCG molecules that alternatingly are oriented with either hydrophilic
or hydrophobic faces to each other. In thisway each TCGmolecule is oriented partiallywith its hydrophilic
face towards the hexameric pore allowing the formation of the column of water inside this pore
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
1998 Alcan Award Lecture Surface electrochemistry - surface science with a joy stick
No full text This lecture gives a review of thermodynamic, spectroscopic, STM and AFM imaging, and X-ray diffraction studies of molecular and ionic adsorption at Au(111) electrodes. In the first part, thermodynamics of adsorption of simple ions such as sulfate, chloride, bromide, and iodide will be discussed. At high coverages, anions adsorbed at a single crystal surface form ordered 2D adlayers. We show that the structure of these adlayers can be studied by STM and surface X-ray diffraction techniques. Next, the information concerning adsorption of simple ions is used to describe mixed adlayers formed by coadsorption of anions and metal adatoms. We demonstrate how to combine electrochemical experiments with in situ polarization-dependent Cu K-edge X-ray absorption spectroscopy to determine the composition and the structure of mixed films formed by deposition of Cu on Au(111) in the presence of SO42-. In the last part we review our efforts to describe coordination of organic molecules to gold electrodes. First, we will discuss adsorption of benzonitrile at the Au(111) electrode surface. We combine electrochemical methods with in situ infrared spectroscopy to describe (i) the energetics of molecular adsorption at the gold electrode surface, (ii) the character of the interaction of the adsorbed molecule with the metal substrate, and (iii) the influence of the electric field on the orientation of the adsorbed molecule. In the last section we describe surface aggregation phenomena. We apply AFM and STM to determine the structure of hemimicelles formed at the Au(111) electrode surface by adsorbed molecules of sodium dodecyl sulfate and we discuss the potential-controlled transformation of these hemimicelles into a condensed monolayer.Key words: surface electrochemistry, electrosorption, surface aggregation, gold electrodes, molecular adsorption, ionic adsorption. </jats:p
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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