1,721,745 research outputs found

    [Rezension zu:] Martin H. Jung: Der Protestantismus in Deutschland von 1815-1870

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    Rezension zu Martin H. Jung: Der Protestantismus in Deutschland von 1815-1870(Kirchengeschichte in Einzeldarstellungen III/3). Leipzig: Evangelische Verlagsanstalt, 2000

    Antihypertensive medication prescription patterns and time trends for newly-diagnosed uncomplicated hypertension patients in Taiwan

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    Abstract Background Knowledge of existing prescription patterns in the treatment of newly-diagnosed hypertension can provide useful information for improving clinical practice in this field. The aims of this study are to determine the prescription patterns and time trends for antihypertensive medication in newly-diagnosed cases of uncomplicated hypertension in Taiwan and to compare these with current clinical guidelines. Methods A total of 6,536 newly-diagnosed patients with uncomplicated hypertension, aged ≥30 years, were identified from the representative 200,000-person sample in the computerized reimbursement database of the National Health Insurance in Taiwan. These patients were followed from 1998 to 2004 with all diagnoses, prescription data and medication charges being retrieved for subsequent analysis. Results Prescription patterns varied by age, gender and clinical facilities, with mono-therapies being found to be dominant in the first year, albeit declining over time. Calcium channel blockers and beta-blockers were the most frequently prescribed antihypertensive drugs, either alone or in combinations. Although least expensive, the prescription rates of diuretics were low, at 8.3% for mono-therapies and 19.9% overall. The prescription rate for angiotensin receptor blockers (ARBs) was elevated considerably over time. After controlling for other related factors by multiple logistic regression analysis, ARBs were found to be prescribed mainly by medical centers or regional hospitals. Conclusion These findings indicate the existence of a gap between current clinical practice and the desired goal of cost-effectiveness in antihypertensive treatment in Taiwan, which should be corrected.</p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Comparative risk and impact assessment for occupational and environmental health

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    In the quantification of burdens of diseases, QALY (quality- adjusted life year) or DALY (disability-adjusted life year) have been used for comparative assessment of population health. By adjusting the survival function with the mean of quality of life (QOL) at every time point t and summing up yearly throughout lifetime, we obtained the quality-adjusted life expectancy (QALE) with the unit of QALY: QALE = integral E[Qol(t vertical bar x(i))]S(t vertical bar x(i))dt Three environmental health issues were empirically assessed as examples: the contamination of underground water by chlorinated hydrocarbons from an electronics factory; the enforcement of helmet law in Taipei city; and occupational policies for protection of offspring of female lead workers. The likelihoods and expected numbers of new cases with liver cancer, head injury, or mentally impaired offspring born to mothers of lead workers were estimated, and these were then multiplied by the quality-adjusted life expectancy lost per case. The results showed that the ground water pollution produced a potential loss of 78 QALM (quality- adjusted life month) for the 1000 people in the downstream community. The enforcement of helmet law in Taipei would save 6240 QALY annually. The expected utility loss of the babies born to female lead workers was about 216 QALY. If the QOL was measured by psychometry, it could be applied in clinical outcome evaluation. If it was extended to consider the cost of illness, the financial burden to the National Health Insurance could be estimated. We conclude that this is a feasible method for comparative health risk/impact assessment for public health and clinical policy decisions
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