24,699 research outputs found
Dr. H. H. Janssen, Latijnse letterkunde
No full textKnecht Daniel. Dr. H. H. Janssen, Latijnse letterkunde. In: L'antiquité classique, Tome 49, 1980. p. 361
Report on Meteorological Research March 1, 1935 (m-1)
No full textThe object of the report was to elucidate in detail the various features of the research program in meteorology being carried on at the Daniel Guggenheim Airship Institute in Akron, Ohio. Mr. L. J. Fangman, of the U.S. Weather Bureau, was collaborating with the author in carrying out work such as a study of autographic records of the various meteorological elements during frontal passages with a view to the possible prediction of the intensity of the accompanying disturbance as it may affect the operation of aircraft and a study of atmospheric gustiness with a view to finding the dependence between frequency end amplitude of velocity fluctuations and the vertical temperature and velocity gradients
Correction: Privileged chiral N-heterocyclic carbene ligands for asymmetric transition-metal catalysis
No full textCorrection for ‘Privileged chiral N-heterocyclic carbene ligands for asymmetric transition-metal catalysis’ by Daniel Janssen-Müller et al., Chem. Soc. Rev., 2017, DOI: 10.1039/c7cs00200a.</p
Hommage de Daniel Janssen, Président du Comité exécutif d'UCB
No full textAllocutions prononcées lors des funérailles de Paul Foriers décédé le 18 mai 1980info:eu-repo/semantics/publishe
(Fourth) Report on Meteorological Activities at the DGAI (8-1-36)(Weather Bureau Copy)
No full textThis report is on the investigations of frontal phenomena at the Daniel Guggenheim Airship Institute in Akron, Ohio from January 1, 1935 through August 1, 1936. The investigation was carried out with the cooperation of the U.S. Bureau of Aeronautics, the U.S. Weather Bureau, the California Institute of Technology, and the Guggenheim Airship Institute. Mr. R.C. Robinson of the Weather Bureau cooperated with the author in carrying out the investigation. The object of the investigation was to determine the intensity of the atmospheric disturbances (i.e. rapidity of wind shift and gustiness) accompanying the passage of cold fronts, along with a study of the characteristics of the air masses involved and other features which might affect the intensity of the disturbance. The report treated thirty cold fronts which passed the station during 1935 to 1936
Archives and Images as Repositories of Time, Language, and Forms from the Past: A Conversation with Daniel Eisenberg
No full textDaniel Akech
No full textabstract: Daniel was a little boy when the war came to his village. He witnessed people being shot and running for shelter. There was no food or water so he drank urine and ate tree leaves.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 24Region: Upper NileThis picture and bio was donated to the "Lost Boys Found" oral history project from The Arizona Lost Boys Cente
Daniel Emmett postcard
No full textPostcard of Daniel Emmett and his home in Mount Vernon, Ohio. Emmett is considered to be the author of the antebellum song "Dixie," written in 1859, which became the unofficial song of the Confederate soldiers during the American Civil War. He was born in Mount Vernon in 1815 and taught himself the fiddle, and later became associated with minstrel shows and helped to define that genre. Minstrel shows traveled around the United States, presenting skits and musical performances. Emmett also composed many other songs, including "Old Dan Tucker," "Turkey in the Straw," and "The Blue Tail Fly." He died in 1904
Cys-loop ligand-gated chloride channels in Dorsal Unpaired Median neurons of Locusta migratoria
No full textThe economic and agricultural importance of locusts can easily be underestimated, given
the widespread use of insecticides. However, areas in Africa and in Asia are frequently affected by
locust swarms, causing devastating consequences to the local food security. Unfortunately, contrary
to intuition, the wide use of broad-spectrum insecticides can increase the probability, duration
and stability of locust outbreaks. Locusts and insects in general are highly adaptable, developing
resistance to a wide range of insecticides and thus raising the need for the development of
improved and novel antiparasitic drugs both more species-selective and more potent. Established
target sites for insecticides are the members of the cys-loop ligand-gated chloride channels. They
mediate important aspects of behaviour through fast inhibitory neurotransmission. In insects, the
cys-loop ligand-gated chloride channels are composed of the glutamate-gated chloride channel
(GluCI), the y-amino butyric-gated chloride channels (GABACI) and histamine-gated chloride channel
(HisCI). They are excellent candidates for the development and design of new insecticidal
compounds, and it is for this reason that our work has been concentrated on these receptors. In
addition, the functional implication of cys-loop ligand-gated chloride channels in dorsal unpaired
median (DUM) neurons deserved our attention. Efferent DUM neurons exert a variety of myo- and
neuromodulatory effects and are involved in numerous behavioural aspects such as flying, jumping
and walking. It is therefore plausible to assume that the cys-loop ligand-gated chloride channels
could have modulatory effect on the excitability of DUM neurons, altering various aspects of the
locust physiology and behaviour. Moreover, this work may provide new insight into the diversity of
the cys-loop LGIC superfamily in different organisms and provide a better understanding of these
channels in general
The objectives
The main objective is to obtain a more detailed insight in the distribution, structure and
functional properties of these cys-loop ligand-gated chloride channels on the cell surface of
locust metathoracic DUM neurons. This was done using electrophysiological methods and molecular
biological methods
The functional expression of the glutamate-gated chloride channel, the GABA-gated chloride channel
and the histamine-gate chloride channels will be studied and pharmacologically characterized, using
the patch clamp techniques. The intention is to establish the DUM neuron as a viable in vitro model
for the study of members of these cys-loop ligand gated chloride channel, in order to screen for
compounds (i.e. toxins, drugs, insecticides,...) targeting these particular channels.
The identification of putative cys-loop ligand-gated chloride channel subunits will be attempted,
using a degenerate RT-PCR and RACE strategy. The sequencing results will allow the comparison of
these channels from different insect species and enhance our understanding of the cys-loop
ligand-gated chloride channel functional genomics. Because the glutamate-gated chloride channels
are exclusively present in invertebrates and thus form excellent targets for the development of
more selective insecticides, our research will be mainly focused on this channel.
The identified cys-loop ligand-gated chloride channel subunits will be cloned and their functional
expression in a heterologous system, such as the Xenopus laevis oocytes will be studied. The aim is
to obtain a reliable in vitro model for the study of kinetics, biophysics and pharmacology of a
single receptor type, without the interference of other receptor channels. These in vitro models
can be exploited to design new pharmacological tools used in research or new drugs for specific
diseases, and for screening of toxins acting on yet unknown targets
Daniel Jau Maper
No full textabstract: Daniel Jau Maper was herding cattle when Arabs attacked his village.
“Lost Boys Found” is an ongoing, interdisciplinary project that is collecting, recording and archiving the oral histories of the Lost Boys/Girls of Sudan. The collection is a work-in-progress, seeking to record the oral history of as many Lost Boys/Girls as are willing, and will be used in a future book.Age: 27Region: Upper NileThis picture and bio was donated to the "Lost Boys Found" oral history project from The Arizona Lost Boys Cente
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