91 research outputs found
Effects of fluoridated milk on artificial enamel carious lesions: a pH cycling study
No full textAbstract not availableA. Itthagarun, S. Verma, R. Lalloo, N.M. King, J.S. Wefel, R.G. Nai
Hidden Sugar – Hidden Fluoride?
No full text Assessing Fluoride Levels of Carbonated Soft Drinks. J.R. Heilman, M.C. Kiritsy, S.M. Levy, J.S. Wefel. Journal of the American Dental Association 130; 11: 1593-1599. </jats:p
Comparison of Artificial White Spots by Microradiography and Polarized Light Microscopy
No full text This work compared lesions produced by three artificial caries systems with natural white spot lesions using both polarized light microscopy and microradiography. The three systems employed were the acidified gelatin gel, diphosphonate surface dissolution inhibitor, and a partially saturated buffer system. When we compared the natural white spot lesions with the artificial caries-like lesions, we found that the acidified gel system reproduced the classical histological zones most frequently. All systems showed a radiopaque surface layer overlying a radiolucent body of the lesion. This radiopaque layer could not be equated with the negatively birefringent surface zone seen in polarized light. </jats:p
Seeded Growth of Calcium Phosphates: Effect of Different Calcium Phosphate Seed Material
No full text The growth of calcium phosphates on seed materials, dicalcium PhosPhate dihydrate (DCPD), tricalcium phosphate (TCP), octacalcium phosphate (OCP), and hydroxyapatite (HAP) in stable supersaturated solutions has been studied under conditions of pH and concentration for which the predominant phases are 1, DCPD, and II, HAP. All seed crystals are good nucleators for DCPD in system I, but, aside from HAP itself, only OCP will readily induce growth under condition II. </jats:p
The Effect of Topical Fluoride Agents on Fluoride Uptake and Surface Morphology
No full text Four topical fluoride agents were evaluated in vitro for their ability to form permanently bound fluoride. APF, NH4F, and Na2SnF6 formed soluble reaction products, while TiF4 did not. Surface coatings were present on those samples that showed higher levels of fluoride after washing. </jats:p
Catechol-O-Methyltransferase Genotype Modulates Cancer Treatment-Related Cognitive Deficits in Breast Cancer Survivors
No full textThe Use of Saturated DCPD in Remineralization of Artificial Caries Lesions in vitro
No full text Dicalcium phosphate dihydrate (DCPD) may play a significant role in the caries lesion since it is a stable calcium phosphate phase under acidic conditions. The reaction of DCPD and fluoride, forming fluor-apatite (FAP), may provide a potentially promising treatment regimen for remineralization of caries lesions in vivo. The purpose of this study was to determine whether a two-step DCPD and inorganic wash with fluoride can remineralize artificial caries-like lesions in vitro. We used the single-section technique to facilitate quantitation of the same tissue before and after the experimental regimen. The two-step remineralizing treatment was repeated three times and consisted of a two-minute saturated DCPD treatment (pH 2.1) followed by a 24-hour inorganic wash. Lesion parameters were recorded before and after treatment by the taking of polarized light photomicrographs of each section after imbibition in several media. The changes in the tissue following treatment were expressed as a percent change in the area of the initial pre-treatment lesion. Significant reductions (p < 0. 02) in lesion pore volume were observed in all aqueous media examined. In the lesions after imbibition in quinoline, remineralization was also apparent from the significant increase in the area of the dark zone following treatment. This two-step DCPD treatment appears to remineralize artificial caries-like lesions effectively, but additional work is needed to determine whether it affords any protection against subsequent cariogenic challenges. </jats:p
The Effect of Several Topical Fluoride Agents on Artificial Lesion Formation
No full text NH4F, Na2SnF6, and TiF 4 were applied to human molars before in vitro lesion formation. Polarized light microscopy was used to evaluate the lesions formed; it showed that only the TiF4 treatment resulted in a reduction in lesion size when compared to APF test halves. </jats:p
Topical Fluoride Application and Lesion Progression in vitro
No full text The objectives of this investigation were to study the effects of topical fluoride application on white spot enamel and the effect that this application would have on a second acid exposure (lesion progression). Artificial white spot lesions of approximately 200 μm were created with an acidified gel technique, central control sections were removed, and the remaining tooth halves were randomly paired, with one half serving as an untreated control while the other received a single four-minute application of 1.23% (w/v) fluoride solution of either NH4F, Na2SnF6, APF, or TiF4. Both tooth halves were sectioned following progression and examined with polarized light microscopy. Lesion depth, internal pore volume, and presence, size and shape of dark zones were determined. The considerable variation among progressed lesions revealed no significant benefit from any topical fluoride treatment. </jats:p
Post-traumatic Stress as the Primary Cause for Cognitive Decline-Not the Whole Story, and Perhaps No Story at All
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