1,721,084 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Autobiographie et Fiction romanesque. Autour des «Confessions » de Jean-Jacques Rousseau. Actes du colloque international organisé par J. Domenech, Nice, 11-13 janvier 1996, (Coll. «Publications de la Faculté des Lettres de Nice ».) 1997
No full textDelon Michel. Autobiographie et Fiction romanesque. Autour des «Confessions » de Jean-Jacques Rousseau. Actes du colloque international organisé par J. Domenech, Nice, 11-13 janvier 1996, (Coll. «Publications de la Faculté des Lettres de Nice ».) 1997. In: Dix-huitième Siècle, n°30, 1998. La recherche aujourd'hui, sous la direction de Michel Delon. p. 670
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Zn-metallothionein complexes studied by Raman spectroscopy.
No full textMetallothioneins (MTs) are low molecular weight, cysteine-rich proteins, with an exceptional heavy metal coordination capacity. These metal chelating peptides play an active role in zinc homeostasis. Although their high heterogeneity, structural and functional studies have been mainly devoted to vertebrate and fungal MTs. Participation of metal ligands other than Cys and the presence of secondary structure elements in metal-MT complexes are fairly unknown, especially in non-vertebrate MTs. Six in vivo-synthesized Zn-MTs, representative of different MT families (mollusc, insect, nematode, echinoderm, plant and vertebrate) were studied by analytic and spectroscopic techniques. The examined MTs contain from 43 to 73 amino acids, among which at least a 30% are Cys, whereas very few are aromatic residues. Zn(II)-MT complexes were heterologously synthesized in E.coli, to obtain aggregates representative of those formed in biological systems. These complexes contain variable amounts of metal and sulfide ions, quantitatively evaluated by analytical measurements. The formation of more than one species (S2-containing and S2-devoid complexes), revealed by ESI-MS spectra, is a constant for all these MTs. The analysis of the Raman spectra gave information about the secondary structure of the metal-MT aggregates. For all
the MT examined, a relevant contribution of beta-turns was shown, whereas in all cases the alfa-helix content resulted almost negligible. As regards Cys sulfurs, almost all Cys residues present in MTs resulted to be involved in the metal coordination, as indicated by the presence of several bands attributable to the metal-S stretching modes at low wavenumbers (< 500 cm-1). The high number of vM-S bands and their broadening suggest the formation of different metal centres. Significantly, Raman bands useful as markers of sulfide bridging ligands were identified. In Zn-CeMT2 (from CElegans) and Zn-QsMT (from plant - Quercus suber) the eventual participation of the His residue in metal binding was evaluated through a curve fitting analysis of the 1630-1565 cm-1 Raman spectral range. His residues resulted to be mainly coordinated in Zn-CeMT2 (~ 90%), whereas in Zn-QsMT His is mainly present as free tautomer (~ 90%). Raman spectroscopy showed to be a powerful technique, able to provide information on the state of the Cys sulfur (metal coordinated and oxidised), the metal binding environment (i.e. the participation of His in metal coordination), as well as on the secondary structure
Research progress on metallothioneins: insights into structure, metal binding properties and molecular function by spectroscopic investigations
No full textMetallothioneins (MTs) are low molecular weight, cysteine-rich proteins with an exceptionally heavy metal coordination capacity. Because of their ability to bind metals and to scavenge oxidant radicals, MTs are considered to play a role in metal homeostasis, metal detoxification and control of the oxidative stress. Although their high heterogeneity on the expression patterns, metal binding abilities and primary structure suggest very diverse functional specializations, the structural and functional studies have been mainly devoted to vertebrate and fungal MTs and their canonical cysteine-metal clusters.
This chapter will be focused on the new methodological procedures settled for the structural characterisation of some metallic MT aggregates. Five zinc complexes of the invertebrate and plant MTs, poorly described up to now in the literature, in addition to one well studied MT from vertebrate family, will be analysed and the new discovered structural features of metal-MT clusters, together with the perspectives on MT research, will be commented. In fact, the application of several spectroscopic techniques such as Raman and IR spectroscopies, Circular Dichroism, can provide new structural information eventually related to the function of the metal binding.
Recombinant expression in E.coli has allowed the biosynthesis of intact metal-MT complexes, well corresponding to native forms, in sufficient quantity and purity for analytical spectrometric and spectroscopic characterization. The spectroscopic analyses of the in vivo-synthesised metal-MTs have recently demonstrated the participation of extra-protein ligands, such as chloride and sulfide ions, in the metal-MT coordination environment of vertebrate, invertebrate and plant MTs.
Recently, some new insights on the structure of metal-MT complexes has been obtained by using Raman and IR spectroscopies, powerful techniques in protein studies. Despite the potentialities of these techniques, to our knowledge they have been scarcely used in MT conformational studies until now. The use of these spectroscopies has resulted to be very useful to approach unambiguously two basic structural points poorly described in MTs: the participation of chloride, sulfide ions and His residues to the metal-coordination sphere and the presence of secondary structure elements. In particular, ordered secondary structures, oppositely to what has been commonly accepted, are present in MTs from vertebrate, invertebrate and plant MTs, and could develop crucial roles in the determination of the functional properties of MTs
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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