394 research outputs found
T. V. Gopal Iyer (1926-2007)
Chevillard Jean-Luc. T. V. Gopal Iyer (1926-2007). In: Bulletin de l'Ecole française d'Extrême-Orient. Tome 94, 2007. pp. 9-12
Scientometric portrait of Ram Gopal Rastogi
Publication productivity of Indian scientist (R.G. Rastogi) has been documented.
Scientometric analysis of 312 papers by Ram Gopal Rastogi published during 1954 to 1992 in various domains: (a) Luni -solar activity and quiet -time E & F- region (57); (b) Equatorial electric field and low and mid latitude iof:osphere (78); (c) Ionospheric E- region irregularities (19); (dj Ionospheric F- region irregularities (32); and (e) Magnetic disturbance effects on the equatorial low and mid latitude ionosphere (23) were analysed. Interdomainery contents and of the number of papers: a+b were 36; b+c and b+d were 20 each; b+e were 16;. c+e were 5; a+e were 3; d+e were 2; and a+d had only one publication. Highest collaborations were with H. Chandra (61), M.R. Deshpande (42), and G. Sethia (19) out of his total 97 collaborators. His highest productivity was during 1978 with 28 papers followed by 19 papers during 1977. The core journals preferred by him for publishing papers were: Indian Journal of Radio & Space Physics, India, and Journal of Atomic & Terrestrial Physics, UK (59 each), followed by Proceedings of the Indian Academy of Sciences, India (34). Most prolific title keywords with their frequencies were: Ionosphere (92); Equatorial (61); F-region (53); Equatorial electrojet region (40), and Magnetic equator (30)
Governance and Development in Karnataka: A Symposium in Economic and Political Weekly
WP 2006-15 July 2006Governance and the “Karnataka Model of Development” Gopal Kadekodi, Ravi Kanbur and Vijayendra Rao; Change in Karnataka Over the Last Generation: Villages and the Wider Context James Manor; The Political Economy of Gram Panchayats in South India Timothy Besley, Rohini Pande and Vijayendra Rao; Dynamics of Local Governance in Karnataka Kripa Ananthpur; Federalism, Urban Decentralization and Citizen Participation Ramesh Ramanathan; Systematic Hierarchies and Systemic Failures: Gender and Health Inequities in Koppal District Gita Sen, Aditi Iyer and Asha George; To Be or Not to Be: Problems in Locating Women in Public Policy Devaki Jai
ICAS:MP Lecture by Niraja Gopal Jayal (Jawaharlal Nehru University)
Chair: Kalpana Kannabiran (Council for Social Development, Hyderabad) 23 September 2019 Venue: CSDS, Seminar Room, 6 pm – 8 pm Niraja Gopal Jayal is Professor at the Centre for the Study of Law and Governance at the Jawaharlal Nehru University, New Delhi. Her book Citizenship and its Discontents (Harvard University Press, 2013) won the Ananda Kentish Coomaraswamy Prize for 2015. She is also the author of Representing India: Ethnic Diversity and the Governance of Public Institutions (Palgrave ..
Abstract 827: Statistical analyses of stable housekeeping gene expression in cancer post-irradiation
Abstract
Ionizing radiation (IR) can induce DNA damage in human cells and result in changes in gene expression. The changes could also include some of the commonly used housekeeping genes (HKG), and thus making them unstable over the time period after being exposed to radiation. Normalization of housekeeping genes is critical for understanding gene expression post-irradiation. Toward the validation of stable HKGs, cancer cell lines from head and neck, non-small cell lung and pancreas were irradiated to 2, 4 and 6 Gy IR doses. Statistical analysis of RNA expression of fourteen HKGs measured at 5 min to 48hrs post-irradiation reveal tradition HKGs such as beta-actin (ACTB) and glucose-6-phosphate-dehydrogenase (G6PD) to be unstable, while TATA-Box Binding Protein (TBP) and Importin 8 (IPO8) was identified as stable HKGs in non-small lung and pancreas cell across all IR doses and time. Interestingly in head and neck cancer, TBP is also found stable across all IR doses and time. The statistical framework used for identification and validation of HKGs can serve as a reliable metric for quantifying gene expression post-irradiation.
Citation Format: Albert R. Wang, Gopal Iyer, Sean Brennan, Shay Bourgeois, Eric Armstrong, Pari Shah, Paul M. Harari. Statistical analyses of stable housekeeping gene expression in cancer post-irradiation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 827. doi:10.1158/1538-7445.AM2017-827</jats:p
ASIP data-plane processor for multi-standard wireless protocol processing
Evolving Multi-Protocol Multi-Band Software Defined Radio (SDR) devices aim at supporting multiple protocols seamlessly and efficiently. The design of such radios necessitates flexibility in physical layer processing, flexibility in routing packets through processing engines and flexibility in radio frequency reception/transmission. This dissertation addresses an efficient implementation of flexible physical layer processing (PHY) for Interleaving, De-Interleaving and linear Minimum Mean Square Error (MMSE) detection in Multiple Input Multiple Output (MIMO) receivers through Application Specific Instruction Set Processors (ASIPs). The thesis defines and develops a WINLAB cognitive radio (WiNC2R) compatible data-plane ASIP architecture along with suitable hardware-software partitioning of the Processing Engine unit. Given the requirement of very significant design time and the lack of the flexibility after design, dedicated ASIC for PHY may not be a viable option although it has the best performance among all available options. The software application running on general purpose processor cannot satisfy the throughput requirements of the wireless standards. ASIPs provide a better trade-off between flexibility and performance, with the advantage of considerably lower design time than ASICs. We design an efficient multi-standard (802.11a, 802.16e/m) supporting Interleaver/De-Interleaver ASIP, satisfying the throughput requirements for all the modulation-schemes/data-rates in both of the standards. It can be programmed to scale for supporting future wireless standards (that use Block Interleaving/De-Interleaving). We also study viability of a flexible MIMO MMSE detector ASIP supporting variable MR (Number of receiving antennas) * MT (Number of transmitting antennas) operations. We have analyzed the implementation of an hardware-centric algorithm for MIMO detection on an ASIP and also improved its performance with the help of techniques such as fixed point implementation, Single Instruction Multiple Data (SIMD) and Very Long Instruction Word (VLIW). Analysis of the design performance results for MIMO ASIP indicates the limitations of hardware-implementation-specific algorithms on ASIP. We also provide the account of design decisions such as custom ports, memory interfaces and registers that are added to the data-plane processor ASIPs in order to substitute them for dedicated hardware engines in the WiNC2R platform.M.S.Includes bibliographical referencesby Mohit Gopal Wan
Scientometric analysis of synchronous references in the Physics Nobel lectures, 1981-1985 : a pilot study
Scientometric analysis of synchronous references in the nine Physics Nobel lectures by Nicolaas Bloembergen (1981), Arthur L. Schawlow (1981), Kai M. Siegbahn (1981), Kenneth G. Wilson (1982), Subrahmanyan Chandrasekhar (1983), William A. Fowler (1983), Carlo Rubbia (1984), Simon van der Meer (1984), and Klaus von Klitzing (1985) indicated high variations: No. of Synchronous References ranged from 24 (Meer) to 283 (Siegbahn); Synchronous Self-References ranged from 5 (Rubbia) to 88 (Siegbahn); synchronous references to others ranged from 10 (Chandrasekhar) to 255 (Wilson); Synchronous Self-Reference Rates ranged from 6.66 % (Rubbia) to 65.51 % (Chandrasekhar); Single-Authored References ranged from 15 (Klitzing) to 160 (Wilson); Multi-Authored References ranged from 4 (Chandrasekhar) to 194 (Siegbahn); Collaboration Coefficient in the synchronous references ranged from 0.14 (Chandrasekhar) to 0.75 (Klitzing); and Recency (age of 50 % of the latest references) ranged from 2 (Klitzing) to 18 (Chandrasekhar) years. Seventy five per cent of the references belonged to journal articles. Highly referred journals were Astrophysical Journal, Physical Review B, Physical Review Letters, Arkiv Fuer Fysik, Surface Science, Physics Letters, and IEEE Transactions on Nuclear Science.
See: Scientometrics Vol. 61 No.1, pp.55-68
Remark on <i>p</I>-<i>d< Operator
Gopal, Dhananjay/0000-0001-8217-2778In this short communication, we show that P-D, operator fall in the class of weakly compatible (respectively, occasionally weakly compatible) in the presence of a unique common fixed point (respectively, multiple common fixed points) of the given maps.CSIR, Govt. of India [25(0215)/13/EMR-II]The first author thanks for the support of CSIR, Govt. of India, Grant No.25(0215)/13/EMR-II.Emerging Sources Citation Inde
The Expression of CD44s in Squamous cell carcinoma of the oral tongue and association with clinicopathological factors and survival outcomes
Master'sMASTER OF SCIENC
Abstract 4121: Androgen receptor as a potential target in non-small cell lung cancer
Abstract
The cancer genome atlas (TCGA) has identified androgen receptor (AR) to be mutated, deleted and amplified across human lung squamous cell carcinoma and adenocarcinoma. Expression of AR is critical for early lung development. However, the intriguing expression of AR in non-small cell lung cancer (NSCLC) opens up an alternative treatment paradigm in the event of onset of clinical resistance to lung cancer drugs. To investigate this potential, a) 10 NSCLC cell lines and 3 control prostate cancer cell lines were stimulated with synthetic AR agonist, R1881 at 24, 48 and 72 hours. 0.5-4-fold RNA and protein expression was found across these lung cancer cell lines when compared to unstimulated cells. b) droplet digital PCR revealed varying copies of AR DNA when benchmarked to prostate AR. c) cell proliferation assays of these cell lines with enzalutamide (MVD3100) treatment resulted in 50-65% cell survival at concentrations ranging from 10 - 25 µM. d) Immunohistochemical staining of AR in a NSCLC human tissue microarray (TMA) revealed 10 out of 88 patients (11%) to have AR positive staining in their tumor. This included 6 adenocarcinomas and 2 squamous cell carcinomas. 8 patients had focal while 2 had diffuse staining. Validation of the TMA performed with whole mount slides confirmed diffuse staining in these 11 samples. Taken together, these findings suggest AR is a potential therapeutic target in NSCLC and further work is underway to test these observations in drug resistant lung cancer cell lines and pre-clinical mouse models.
Citation Format: Sean Brennan, Albert R. Wang, Hope Beyer, Dylan Wiese, Darya Buehler, Anwaar Saeed, Andrew M. Baschnagel, Gopal Iyer. Androgen receptor as a potential target in non-small cell lung cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 4121. doi:10.1158/1538-7445.AM2017-4121</jats:p
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