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Pregnancy in kidney transplant recipients and in women on chronic dialysis
No full textTrudnoća kod pacijentica s krajnjim stadijem bubrežne bolesti koje su na dijalizi ili nakon transplantacije bubrega rijetka je, ali moguća. Plodnost može biti smanjena zbog hormonalnih i ne-hormonalnih faktora. Nakon transplantacije bubrega, reproduktivna funkcija često se poboljšava, a menstrualni ciklusi mogu se ponovno uspostaviti. Unatoč potencijalnim komplikacijama, trudnoće kod ovih pacijentica mogu biti uspješne uz pažljivo, multidisciplinarno praćenje.
Prema podacima Kliničkog bolničkog centra Zagreb (1988.–2024.) zabilježeno je 15 trudnoća među 12 žena u dobi od 25 do 43 godina. Od tih su trudnoća dvije bile tijekom nadomještanja bubrežne funkcije hemodijalizom, jedna tijekom kontinuirane ambulatorne peritonealne dijalize, a 12 ih je zabilježeno nakon transplantacije. Pacijentice s transplantiranim bubregom koristile su imunosupresive, većinom kombinaciju ciklosporina + azatioprina + metilprednizolona/prednizona ili kombinaciju takrolimusa + azatioprina + prednizona.
Jedanaest trudnoća dovršeno je carskim rezom, a 4 vaginalnim porodom. Zabilježena su 4 spontana pobačaja. Pet trudnoća bilo je prijevremeno, s porodom između 31. i 36. tjedna trudnoće. Šestero novorođenčadi imalo je nisku porođajnu masu (<2500g), iako je samo troje od njih bilo prijevremeno rođeno.
Opstetričke komplikacije uključivale su omotanu pupčanu vrpcu oko vrata djeteta pri 4 porođaja. Troje novorođenčadi imalo je komplikacije: jedno je imalo kongenitalnu dijafragmalnu herniju, drugo je imalo nekrotizirajući enterokolitis, a treće je imalo asfiksiju i sepsu, što je zahtijevalo reanimaciju koja je bila uspješna. Komplikacije u majki bile su rijetke, jedna pacijentica imala je povišen krvni tlak, dok je druga imala urinarnu infekciju.
Zaključno, iako trudnoća kod pacijentica sa završnim stadijem kronične bubrežne bolesti na dijalizi ili nakon transplantacije bubrega ostaje visokorizična, nije nemoguća. Napredak u dijaliznim tehnologijama i imunološkoj terapiji poboljšao je ishode za majku i dijete. Multidisciplinarni pristup ključan je za osiguranje najbolje moguće skrbi i ishoda za ove visokorizične trudnoće.Pregnancy in patients with end-stage renal disease (ESRD) who are on dialysis or who have undergone kidney transplantation is rare but possible. Fertility may be affected by both hormonal and non-hormonal factors. However, after kidney transplantation, reproductive function often improves, and many women resume regular menstrual cycles. Despite the potential for complications, successful pregnancies can occur in these patients with careful, multidisciplinary management.
A study conducted at the University Hospital Centre Zagreb from 1988 to 2024 analyzed 15 pregnancies among 12 women aged 25 to 43 years. Of these pregnancies, two occurred while the patients were on hemodialysis, one during continuous ambulatory peritoneal dialysis, and 12 after kidney transplantation. Most of the transplant recipients were treated with immunosuppressive medications such as cyclosporine combined with azathioprine and methylprednisolone/prednisone, or tacrolimus combined with azathioprine and prednisone.
The outcomes revealed that 11 pregnancies resulted in deliveries via cesarean section, while four were delivered vaginally. There were four miscarriages. Five pregnancies were preterm, with deliveries occurring between 31 and 36 weeks of gestation. Six children were born with low birth weight (less than 2500 grams), although only three of these were preterm.
Obstetric complications included umbilical cord issues in four deliveries. Three newborns experienced complications: one had a Bochdalek hernia, another was suspected of having necrotizing enterocolitis, and one suffered from asphyxia and sepsis, requiring successful resuscitation. Maternal complications were relatively rare, with one patient experiencing elevated blood pressure and another suffering from a urinary tract infection.
In conclusion, while pregnancy in patients with ESRD on dialysis or after kidney transplantation carries significant risks, it is not impossible. Advances in dialysis and immunosuppressive therapy have improved outcomes for both mothers and their children. A multidisciplinary approach is essential to provide the best possible care and outcomes for these high-risk pregnancies
Pregnancy in kidney transplant recipients and in women on chronic dialysis
No full textTrudnoća kod pacijentica s krajnjim stadijem bubrežne bolesti koje su na dijalizi ili nakon transplantacije bubrega rijetka je, ali moguća. Plodnost može biti smanjena zbog hormonalnih i ne-hormonalnih faktora. Nakon transplantacije bubrega, reproduktivna funkcija često se poboljšava, a menstrualni ciklusi mogu se ponovno uspostaviti. Unatoč potencijalnim komplikacijama, trudnoće kod ovih pacijentica mogu biti uspješne uz pažljivo, multidisciplinarno praćenje.
Prema podacima Kliničkog bolničkog centra Zagreb (1988.–2024.) zabilježeno je 15 trudnoća među 12 žena u dobi od 25 do 43 godina. Od tih su trudnoća dvije bile tijekom nadomještanja bubrežne funkcije hemodijalizom, jedna tijekom kontinuirane ambulatorne peritonealne dijalize, a 12 ih je zabilježeno nakon transplantacije. Pacijentice s transplantiranim bubregom koristile su imunosupresive, većinom kombinaciju ciklosporina + azatioprina + metilprednizolona/prednizona ili kombinaciju takrolimusa + azatioprina + prednizona.
Jedanaest trudnoća dovršeno je carskim rezom, a 4 vaginalnim porodom. Zabilježena su 4 spontana pobačaja. Pet trudnoća bilo je prijevremeno, s porodom između 31. i 36. tjedna trudnoće. Šestero novorođenčadi imalo je nisku porođajnu masu (<2500g), iako je samo troje od njih bilo prijevremeno rođeno.
Opstetričke komplikacije uključivale su omotanu pupčanu vrpcu oko vrata djeteta pri 4 porođaja. Troje novorođenčadi imalo je komplikacije: jedno je imalo kongenitalnu dijafragmalnu herniju, drugo je imalo nekrotizirajući enterokolitis, a treće je imalo asfiksiju i sepsu, što je zahtijevalo reanimaciju koja je bila uspješna. Komplikacije u majki bile su rijetke, jedna pacijentica imala je povišen krvni tlak, dok je druga imala urinarnu infekciju.
Zaključno, iako trudnoća kod pacijentica sa završnim stadijem kronične bubrežne bolesti na dijalizi ili nakon transplantacije bubrega ostaje visokorizična, nije nemoguća. Napredak u dijaliznim tehnologijama i imunološkoj terapiji poboljšao je ishode za majku i dijete. Multidisciplinarni pristup ključan je za osiguranje najbolje moguće skrbi i ishoda za ove visokorizične trudnoće.Pregnancy in patients with end-stage renal disease (ESRD) who are on dialysis or who have undergone kidney transplantation is rare but possible. Fertility may be affected by both hormonal and non-hormonal factors. However, after kidney transplantation, reproductive function often improves, and many women resume regular menstrual cycles. Despite the potential for complications, successful pregnancies can occur in these patients with careful, multidisciplinary management.
A study conducted at the University Hospital Centre Zagreb from 1988 to 2024 analyzed 15 pregnancies among 12 women aged 25 to 43 years. Of these pregnancies, two occurred while the patients were on hemodialysis, one during continuous ambulatory peritoneal dialysis, and 12 after kidney transplantation. Most of the transplant recipients were treated with immunosuppressive medications such as cyclosporine combined with azathioprine and methylprednisolone/prednisone, or tacrolimus combined with azathioprine and prednisone.
The outcomes revealed that 11 pregnancies resulted in deliveries via cesarean section, while four were delivered vaginally. There were four miscarriages. Five pregnancies were preterm, with deliveries occurring between 31 and 36 weeks of gestation. Six children were born with low birth weight (less than 2500 grams), although only three of these were preterm.
Obstetric complications included umbilical cord issues in four deliveries. Three newborns experienced complications: one had a Bochdalek hernia, another was suspected of having necrotizing enterocolitis, and one suffered from asphyxia and sepsis, requiring successful resuscitation. Maternal complications were relatively rare, with one patient experiencing elevated blood pressure and another suffering from a urinary tract infection.
In conclusion, while pregnancy in patients with ESRD on dialysis or after kidney transplantation carries significant risks, it is not impossible. Advances in dialysis and immunosuppressive therapy have improved outcomes for both mothers and their children. A multidisciplinary approach is essential to provide the best possible care and outcomes for these high-risk pregnancies
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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