912 research outputs found
"Replication Data for: Public Sector Innovation Outcome-driven Sustainable Development in Bangladesh: Applying the DARDL Simulations and KRLS Machine Learning Algorithm Approaches".
No full text"The file is a part of "Replication Data for: Public Sector Innovation Outcome-driven Sustainable Development in Bangladesh: Applying the DARDL Simulations and KRLS Machine Learning Algorithm Aapproaches".</font
Regulation of Foxn4 during retina development
No full textTranscription factor forkhead box N4(Foxn4) is a key regulator involved in a variety of biologic processes in development and metabolism. In particular, Foxn4 plays an essential role in the genesis of amacrine and horizontal neurons from neural progenitors in the retina. Although the functions of Foxn4 have been well established, the transcriptional regulation of Foxn4 expression during progenitor cell differentiation remains unclear. The goal of this dissertation is to identify regulatory mechanisms that define the expression of Foxn4 during retinogenesis. Four evolutionarily conserved regions (CR1-CR4) from non-coding sequences of Foxn4 gene were computationally predicted as cis-elements. Their gene regulatory potential was individually tested in developing chick and mouse embryonic retina using electroporation transfection technique with a reporter assay system. In this dissertation, I describe that CR4.2 (a 129 bp DNA fragment of CR4, located approximately 50kb upstream of Foxn4 transcription start site) functions as a novel cis-regulator that directs retinal cell type specific gene expression. CR4.2 is preferentially active in the Foxn4 expressing cells, primarily in the differentiating and differentiated horizontal and amacrine cells as shown by reporter assays. Specific trans-acting factors, e.g., Meis1, were found to interact with CR4.2 by electrophoretic mobility shift assays (EMSA). Mutation and/or deletion of the Meis1 binding motif through site-directed mutagenesis diminishes the ability of CR4.2 to drive reporter GFP expression. Furthermore, the role of Meis1 in regulating Foxn4 expression during progenitor cell differentiation was determined using a RNAi-based gene silencing assay. Knockdown of Meis1 by short hairpin RNA (shRNA) specific to Meis1 genes abolishes gene regulatory activity of CR4.2, and further diminishes the endogenous level of Foxn4 expression. In addition, cells with Meis1 knockdown failed to differentiate into horizontal cells. Taken together, I demonstrate that Meis1 transcription factor regulate the expression of Foxn4 expression and horizontal cell lineage development in the vertebrate retina via their interactions with CR4.2. These findings provide new insights into molecular mechanisms that govern gene regulation in retinal progenitors and vertebrate retinal cell development.Ph. D.Includes bibliographical referencesby Mohammed Monirul Isla
Textile industry in Bangladesh and challenges of growth
No full textThe importance of the textile industry in the economy of Bangladesh is very high. The garments manufacturing sector earned $19 billion in the year to June 2012, one of the impoverished nation's biggest industries. Currently this industry is facing great challenges in its growth rate. The major reasons for these challenges can be the global recession, unfavorable trade policies, internal security concerns, the high cost of production due to increase in the energy costs, different safety issues specially fire, etc. Depreciation of Bangladeshi Taka that significantly raised the cost of imported inputs, rise in inflation rate, and high cost of financing has also effected seriously the growth in the textile industry. As a result neither the buyers are able to visit frequently Bangladesh nor are the exporters able to travel abroad for effectively marketing their products. With an in-depth investigation it was found that the Bangladesh textile industry can be brought on top winning track if government and others individuals takes serious actions in removing or normalizing the above mentioned hurdles. Additionally, the government should provide subsidy to the textile industry, minimize the internal dispute among the exporters, withdraw the withholding and sales taxes etc. Purchasing new machinery or enhancing the quality of the existing machinery and introducing new technology can also be very useful in increasing the research and development (R and D) related activities that in the modern era are very important for increasing the industrial growth of a country
Electrical conductivity depth modelling with a multireceiver EMI sensor for prospecting archaeological features
No full textAbstract not availableTimothy Saey, Philippe De Smedt, Eef Meerschman, Mohammad Monirul Islam, Fun Meeuws, Ellen Van De Vijver, Alexander Lehouck, and Marc Van Meirvenn
A Real-Time Dataset of Pond Water for Fish Farming using IoT devices
No full textThis is the real-time dataset. This dataset is created for monitoring the real-time aquatic environment using an IoT framework. Three sensors named pH, Temperature, and turbidity along with Arduino controller are used for monitoring the water quality of 5 ponds.It has 4 columns and 591 rows. They are- pH, Temperature, Turbidity, and Fish. Here fish is the target variable and others are the independent variable. There are 11 fish categories, 86 pH distinct values, 46 temperature distinct values, and 85 Turbidity distinct values
Effective Operations and Maintenance (O&M) practices of vehicles: a case study on LGED
No full textThis dissertation is submitted in partial fulfillment of the requirements for the degree of Masters in Procurement and Supply Management, 2015.Cataloged from PDF version of thesis report.LGED has the reputation as an “island of excellence” in the Government, with high standards of professionalism, and comparatively robust risk management systems. The report begins with a brief assessment of external environmental factors that affect LGED’s ability to adopt reforms to effectively address potential fiduciary & operational risks throughout the value chain of public expenditure for rural and urban infrastructure. This study has examined the present operations management practices of large fleet of vehicles at LGED Head Quater and analyze its effectiveness and compliance with existing rules and regulations of Bangladesh. To fulfill the overall objective of this study has undergone an in-depth procedure on verification of vehicle usages and allocation of vehicle procedures, it estimate preparation and approval procedures for maintenance, procurement process, has also checked procurement process as a tool for Public Procurement Rules (PPR-2008). Factors at the national level include weaknesses in electoral, legislative, judicial and agency accountability, outmoded civil service rules and practices, lack of national audit capacity, and high levels of corruption. Progress in nationwide reforms for combating corruption and improving financial management and procurement has been encouraging in recent years, but there is a risk that it may not be sustained by the next political government. At the sub-national level, LGED is subject to two lines of accountability. On the one hand, LGED has a sizeable budget of its own for implementing infrastructure programs at various levels of government. Here there is a strong emphasis on administrative and financial procedures to ensure the probity, integrity and effectiveness of activities. On the other hand, LGED also implements and manages rural and urban infrastructure funded under Annual Development Program allocations of sub national jurisdictions. In these cases, while there is a clearer accountability link to beneficiaries through their elected officials, risks can still arise due to weaknesses in local governance in planning, decision making and management. These risks need to be mitigated through local government reforms that will create a more efficient, effective and transparent environment within which LGED can function in the future. The report gives a brief internal organizational assessment of LGED, reviewing its evolution from a rural works component of the integrated rural development program of the early 1960s to its formalization and rapid growth as a public sector department. Key functions are assessed, including human resources and financial management, procurement, engineering and ICT systems, corporate governance, and approach to land use and resettlement. The report confirms LGED’s excellent reputation for professionalism, including quality delivery of many contracts on time and on budget. Although information and communication systems are relatively advanced in LGED compared to other government departments, the use of many different, non-integrated systems with inadequate supervision by core staff with ICT skills make it difficult for LGED to gather critical information needed to compare the results of the various projects, and complicates the reporting and control procedures within LGED (e.g. benchmarking, and detecting patterns indicating possible collusion on bids).
It has been discussed elaborately the strategy for benefits of improvement of communication system, its contribution to education sector, women empowering through women participation in rural infrastructure, community and local administration development as well as poverty reduction through participation of local level stakeholders and beneficiaries etc.S.M. Monirul IslamM. Procurement and Supply Managemen
Supplemental Material, sj-pdf-1-ccx-10.1177_10732748211027169 - Comparison of Urban-Rural Readmission Rates After Colorectal Cancer Surgery: Findings From a Privately Insured Population
No full textSupplemental Material, sj-pdf-1-ccx-10.1177_10732748211027169 for Comparison of Urban-Rural Readmission Rates After Colorectal Cancer Surgery: Findings From a Privately Insured Population by Mesnad Alyabsi, Mary Charlton, Jane Meza, K. M. Monirul Islam, Amr Soliman and Shinobu Watanabe-Galloway in Cancer Control</p
Allowing for diversity: State-Madrasa relations in Bangladesh
Full text linkWithin South Asia, Bangladesh has apparently been most successful in implementing state administered madrasa modernization: 30 per cent of secondary students in Bangladesh are in Aliya (reformed) madrasas. Given the current emphasis on madrasa reform programmes by many donor agencies, this study attempts to understand the nature of madrasa reforms in Bangladesh and to identify factors that led to acceptance of the programme within the religious establishment. The study argues that Aliya madrasas have indeed been able to combine secular subjects with religious education. On the other hand, while some present day Aliya madrasas might have converted from the traditional Qomi madrasas, as argued by some authors, these state reformed madrasas have failed to displace the Qomi madrasas’ control over the Bangladeshi religious establishment. It is the Qomi madrasa students that are being trained to fill religious positions in Bangladeshi mosques. Aliya madrasa students, on the other hand, are being trained to compete for jobs teaching the children enrolled in the secular schools. The control over religious authority and public interpretation of Islam remains in the hands of the ulema of the Qomi madrasas. Therefore, the study argues that it is misguided to see the Bangladeshi madrasa reform programme as a model for a more liberal interpretation of Islam, which is the focus of current reform efforts. Rather it is a very good model for making madrasas an effective tool for promoting education in conservative societies, where there is a clear demand for combining secular education with a strong religious input. Also, it argues that good financial incentives alone do not explain the rise of Aliya madrasas. The spread of the Aliya madrasa is embedded in a complex interaction between Islam and the Bengali language movement, in pre- and post- liberation (1971) politics, and in the support for the Aliya tradition within an influential segment of the Bangladeshi religious establishment, that is Jamiat-i-Islami. The paper thus argues that in studying madrasa reform programmes, it is important to be clear about the objectives of the reform. Modern interpretations of Islam within madrasas cannot be achieved simply through the introduction of secular subjects. They are only possible if the leadership of Qomi madrasas is successfully convinced of the need for a modern reinterpretation of religious texts and is supported in that process
M. Monirul Islam and
No full textA comparative study on the adverse effects of two anti-tuberculosis drugs regimen in initial two-month treatment perio
Assessment of Drought and Zinc Stress Tolerance of Novel Miscanthus Hybrids and Arundo donax Clones Using Physiological, Biochemical, and Morphological Traits
No full textHigh-yield potential perennial crops, such as Miscanthus spp. and Arundo donax are amongst the most promising sources of sustainable biomass for bioproducts and bioenergy. Although several studies assessed the agronomic performance of these species on diverse marginal lands, research to date on drought and zinc (Zn) resistance is scarce. Thus, the objective of this study was to investigate the drought and Zn stress tolerance of seven novel Miscanthus hybrids and seven Arundo clones originating from different parts of Italy. We subjected both species to severe drought (less than 30%), and Zn stress (400 mg/kg−1 of ZnSO4) separately, after one month of growth. All plants were harvested after 28 days of stress, and the relative drought and Zn stress tolerance were determined by using a set of morpho-physio-biochemical and biomass attributes in relation to stress tolerance indices (STI). Principal component analysis (PCA), hierarchical clustering analysis (HCA) and stress tolerance indices (STI) were performed for each morpho-physio-biochemical and biomass parameters and showed significant relative differences among the seven genotypes of both crops. Heatmaps of these indices showed how the different genotypes clustered into four groups. Considering PCA ranking value, Miscanthus hybrid GRC10 (8.11) and Arundo clone PC1 (11.34) had the highest-ranking value under both stresses indicating these hybrids and clones are the most tolerant to drought and Zn stress. In contrast, hybrid GRC3 (−3.33 lowest ranking value) and clone CT2 (−5.84) were found to be the most sensitive to both drought and Zn stress
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