1,720,966 research outputs found
Implementing a proctored ALEKS-based adaptive learning strategy to evaluate student preparedness and predict success in Calculus I at the University of Alaska FairbanksANKS
Full text linkMaster's Project (M.S.) University of Alaska Fairbanks, 2021In Fall 2016, the Department of Mathematics and Statistics (DMS) at the University of Alaska Fairbanks
(UAF) initiated a study to determine if the Assessment and LEarning in Knowledge
Spaces Placement, Preparation, and Learning test (ALEKS PPL), given under proctored conditions, can be
an effective tool for measuring student preparedness and predicting success in Calculus I while controlling
for enrollment and demographic information. The study includes 583 students who took a Calculus I course
in Fall 2016, Fall 2017, Spring 2018, Fall 2018, Spring 2019, and Spring 2020 semesters and took a
Proctored ALEKS PPL test (PAPL). Of the 583 students, 301(52%) students obtained at least a score of 75
on the PAPL test, and 338 (58%) were successful in the Calculus I course. The average score on the PAPL
test was 13 points higher for the students who had been successful in Calculus I (P < 0.0001, Welch’s t-test). Logistic regression showed that each additional score on the PAPL test was associated to increase the
odds of success in Calculus I by a factor of 1.0843, or 8.43%, when all other factors were fixed (95% CI:
1.07 - 1.1, P < 0.0001). This study recommends implementing the PAPL test as an adaptive learning tool
and a requirement for Calculus I at UAF and establishing a student-centered standard to address the student
knowledge gap in precalculus
EFFECT OF POST-HARVEST TREATMENTS ON QUALITY AND SHELF LIFE OF PINEAPPLE FRUITS AT AMBIENT STORAGE CONDITION
Full text linkA Thesis
Submitted to the Faculty of Agriculture,
Sher-e-Bangla Agricultural University, Dhaka,
In Partial fulfillment of the requirements
for the degree of
MASTER OF SCIENCE
IN
HORTICULTUREThe present study conducted at the laboratories of the Department of Horticulture,
Sher-e-Bangla Agricultural University, Dhaka-1207 during the period from 8 Janurary
2020 to 26 January 2020. The experiment was carried out to investigate the role of
different preservatives in extending the shelf life of pineapple fruits and improve the
shelf life and post-harvest quality of pineapple fruits at ambient storage condition. A
total of nine postharvest treatments viz., T
1
= Fruit dipping in Napthalene Acetic Acid
(NAA) at 100 mg L
-1
and kept in open condition; T
2
= Fruit dipping in Gibberellic
Acid (GA
3
) at 100 mg L
-1
and kept in open condition; T
3
= Fruit dipping in Salicylic
Acid (SA) at 5 m M L
-1
and kept in open condition; T
4
= Fruit dipping in Maleic
Hydrazide (MH) at 500 mg L
-1
and kept in open condition; T
5
= Covering with
perforated polythene; T
6
= Covering with newspaper bag; T
7
= Covering with dry
straw; T
8
= Hot water treatment, and T
9
= Control were used on fruit to investigate
physico-chemical qualities and shelf life of pineapple cv. Honey Queen. Experiment
was laid out in Complete Randomized Design (CRD) with three replications. Study
revealed that among the different treatments, fruits treated with GA
3
showed delayed response of ripening and increase shelf life (18.50 days). At 15 days
after storage (DAS), skin colour remained quarter yellow (average score: 3.4), crown
condition good with slight tip yellowing (average score: 2.2), slightly infected and
10% fruit decay with high juice content (70.23%), whereas, fruits showed
considerably higher amount of TSS (20.25°Brix), total sugar (13.91%) and ascorbic
acid content (20.13 mg 100 g pulp
-1
) with less weight loss (10.57%) when fruits
treated with GA
3
at 100 mg L
-1
. However, among the other treatments, SA (5.0 mM)
and MH (500 mg L
-1
) performed well in terms of fruit physico-chemical properties
and shelf life
GENETIC DIVERSITY AND CHARACTERS ASSOCIATION IN BOTTLE GOURD (Lagenaria siceraria L.)
Full text linkA Thesis
submitted to the Faculty of Agriculture,
Sher-e-Bangla Agricultural University, Dhaka,
in partial fulfillment of the requirements
for the degree of
MASTER OF SCIENCE
IN
GENETICS AND PLANT BREEDINGThe experiment was carried out using seventeen genotypes of bottle gourd
(Lagenaria siceraria L.) at the experimental field of Sher-e-Bangla
Agricultural University during March, 2019 to September, 2019. The main
objective of the experiment was to measure the genetic variability among the
genotypes for yield and yield related contributing characters in bottle gourd. It
helps to select the desirable parents (genotypes) for developing new desired
breeding populations. Among the genotypes, there were significant variations
for all the traits studied here. It was observed that, the high genotypic coefficient
of variation (GCV) was related to 100 seed weight (28.61), number
of seed per fruit (27.31), number of primary branches (26.46), fruit length
(24.06), and yield per plant (21.62). On the other hand, the low genotypic coefficient
of variation (GCV) was observed for days to first male flowering
(1.58), days to first fruit harvest (1.94), days to first female flowering (2.01),
tendril length (5.54) and seed length (5.76). In all cases, it clearly indicated
that, phenotypic variances were higher than the genotypic variances. The
highest heritability was found in 100 seed weight (81.48). But the low genetic
advance in percent of mean was observed in days to first male flowering
(1.65) which indicated the involvement of non-additive gene effects and these
effects were responsible for the expression of this characters, such kind of
traits might not be considered for selection. On the other hand, the high
genetic advance in percent of mean was observed for 100 seed weight (53.21)
and number of primary branches (48.73) per plant with high heritability
which indicated the active involvement of additive gene control and selection
for such kind of characters would be highly effective for genetic
improvement. The highly significant positive correlation was found with days
to first female flowering (0.960). The maximum direct contribution towards
yield was fruit weight (0.879) followed by no of fruit per plant (0.861). The
highest intra cluster distance was found in cluster I (0.992) and the lowest was
found in cluster II (0.628). Among five clusters the highest inter cluster
distance was observed between cluster I and cluster II (0.364) and the lowest
between cluster V and cluster III (0 .004). Considering all the characters
related to yield along with associate characters, the genotypes Diana, BG-
7092 and BG- 6818 might be selected as the most promising genotypes for
future breeding programme
Selective Inference for Bullet Comparisons in Forensic Analysis
Full text linkIn forensic science, it is important to decide whether two bullets were fired from the same gun or two different guns. Algorithms address this problem by comparing striations engraved on the bullets as they speed through a barrel. Advancements in microscopic technology have made it possible to digitally 3d image this striations at different parts of the bullet. These areas are then compared pairwise, leading to a set of similarity measures. Using the familiar NHST framework, we set up a two-sample test to determine whether there is enough similarity in the measurements to reject a null hypothesis of bullets from two different guns. The traditional t-test fails to control Type I error in this scenario, because groups can only be assigned after the similarity between areas is determined. We derive a distributional adjustment using order statistics to fix the bias introduced by this selection. By conditioning upon the selection process, this method controls the inflation of Type I errors caused by group selection. Simulations show that our method keeps Type I error rates close to the nominal level. We also provide a power analysis
Investigating the Unique Mechanism of Action of CADA Analogs for Down-Modulating CD4, Sortilin, and ACE2
Full text linkThe small molecule cyclotriazadisulfonamide (CADA) has been found to inhibit the replication of human immunodeficiency virus (HIV) and human herpesvirus type 7 in cell cultures. It works by down-modulating human CD4 (hCD4) and blocking co-translational translocation of the nascent protein across the endoplasmic reticulum (ER) membrane, which prevents the entry of HIV virus into target cells. The key amino acid residues that are critical for sensitivity to CADA are glutamine (Q-15) and proline (P-20) in the hCD4 signal peptide (SP). It has been proposed that CK147 may bind with the hCD4 signal peptide through a dipole-dipole interaction between the N,N-dimethylaminobenzenesulfonyl side-arm of CK147 and the amide side chain of glutamine (Q-15) of hCD4 SP, forming a folded conformation similar to the transitory state during translocation. It was also proposed that CK147 might interact with the CD4 signal peptide through hydrogen bonding between the sulfonamide oxygen atom of one of the side arms of CK147 and the hydrogen atom of the amide side chain of the glutamine (Q-15) of the CD4 SP.The aim of this research was to synthesize deuterium-labeled CADA analogs and signal peptides to determine the structure of the complex formed between the small molecule and the hCD4 signal peptide, as well as to study the interactions between CADA analog (CK147) and hCD4 SP through two-dimensional infrared spectroscopy (2D IR). Another aim was to synthesize a library of CADA analogs with enhanced potency and selectivity towards the down-modulation of several proteins (CD4, ACE2, sortilin) with the establishment of a pharmacokinetic profile of various biologically active CADA analogs. To achieve these goals, deuterium-labeled CADA analogs (CK147 and TL020) and several signal peptides (hCD4, mCD4, Q19A mCD4, Q16A Q19A mCD4) were synthesized. Also, a library of new CADA analogs was synthesized with modified arylsulfonamide side-arms to better understand the interaction of CADA analogs with SPs. In order to explore the selectivity of CADA analogs towards different signal peptides, a new class of CADA analogs was synthesized by modifying the isobutyl head group. At last, a set of potential bioactive small molecules, TL020, TL027, and VGD020 have been uncovered. These promising compounds have the ability to reduce the expression of angiotensin-converting enzyme-2 (ACE2), suggesting a potential therapeutics to effectively alleviate SARS-CoV-2 infection
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
APPJ
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