169,495 research outputs found

    Isenberg Gerhard — Existenzgrundlagen in Stadt - and Landesplanung

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    C A. Isenberg Gerhard — Existenzgrundlagen in Stadt - and Landesplanung. In: Population, 22ᵉ année, n°2, 1967. p. 336

    Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity

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    When purified under rigorous conditions, some murine anti-double-stranded-DNA (anti-dsDNA) antibodies actually bind chromatin rather than dsDNA. This suggests that they may actually be antinucleosome antibodies that only appear to bind dsDNA when they are incompletely dissociated from nucleosomes. Experiments in murine models suggest that antibody - nucleosome complexes may play a crucial role in the pathogenesis of glomerulonephritis in systemic lupus erythematosus. Some human monoclonal anti- DNA antibodies are pathogenic when administered to mice with severe combined immunodeficiency (SCID). Our objective was to achieve stable expression of sequence-altered variants of one such antibody, B3, in Chinese hamster ovary (CHO) cells. Purified antibodies secreted by these cells were tested to investigate whether B3 is actually an antinucleosome antibody

    Information visualization on interactive tabletops in work vs. public settings

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    Digital tabletop displays and other large interactive displays have recently become more affordable and commonplace. Due to their benefits for supporting collaborative work—when compared to current desktop-based setups—they will likely be integrated in tomorrow’s work and learning environments. In these environments the exploration of information is a common task. We describe design considerations that focus on digital tabletop collaborative visualization environments. We focus on two types of interfaces: those for information exploration and data analysis in the context of workplaces, and those for more casual information exploration in public settings such as museums. We contrast design considerations for both environments and outline differences and commonalities between them

    Studying direct-touch interaction for 2D flow visualization

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    Traditionally, scientific visualization research concentrates on the development and improvement of interactive techniques to support expert data analysis. While many scientific visualization tools have been developed for desktop environments and individual use, scenarios that go beyond mouse and keyboard interaction have received considerably less attention. We present a study that investigates how large-display direct-touch interaction affects data exploration and insight generation among groups of nonexperts exploring 2D vector data. In this study, pairs of participants used interaction techniques to customize and explore 2D vector visualizations and collaboratively discussed the process to develop their own understanding of the data sets

    A 2 h periodic variation in the low-mass X-ray binary Ser X-1

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    Spectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Dr. Edward P. Wimberly, ITC, July 2011

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    This video is a conversation with Dr. Edward P. Wimberly. Dr. Wimberly talks about his book, "No Shame in Wesley's Gospel: A Twenty-First Century Pastoral Gospel". Brad Ost, AUC Woodruff Library, is the interviewer
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