1,720,993 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Primary treatment strategy in elderly patients with hormone receptor positive early breast cancer: is breast cancer surgery.
No full textBackground: Older age, ECOG performance status,
major comorbidities and concomitant medications influence
the primary treatment strategy of hormone receptor
positive (HR+) early breast cancer (EBC) patients. In case
of frail patients, oncologist may choose primary endocrine
therapy (ET) instead of breast cancer surgery (BCS) even
if its clinical impact is still unknown.
Methods: We performed a retrospective study on women
aged 75 years and older with HR+ EBC diagnosed at the
Modena Cancer Center from 2010 to 2016. According to
primary treatment strategy patients were divided into two
groups: patients who underwent BCS (BCS group) versus patients treated with only ET (ET group). Patients’ clinical
data and tumor characteristics were collected. Disease Free
Survival (DFS) and Breast cancer-specific survival (BCSS)
were estimated by long rank test and Kaplan-Meier curves.
Results: 143 patients were involved in the study: 105 in
BCS group and 38 in ET one. Patients who underwent surgery
had significantly better ECOG (p=0.000001), low
tumour grade (p=0.04) and early clinical stage (p=0.0001)
compared to those in the ET group. In patients with negative
lymph-nodes at the diagnosis, tumor stage I-II and low
ki67 (<20%), BCS did not improve 5-years DFS in univariate
and multivariate analysis (p = 0.099, 95%CI
0.152-1.175). No differences were found in terms of
5-years BCSS between the two groups (p = 0.195).
Conclusions: Stage I-II at the diagnosis, negative axillary
lymph nodes and low ki67 identified a subgroup of HR+
EBC patients aged > 75 with low risk of disease progression
who may not benefit from primary BCS. In elderly
frail patients, primary ET instead of BCS could be a valid
treatment strategy that should be considered on a case-bycase
basis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
PROGNOSIS AND RESPONSE TO NEOADJUVANT CHEMOTHERAPY ACCORDING TO HER2 EXPRESSION IN EARLY BREAST CANCER: a retrospective single institution analysis
No full textBackground: The assessment of HER2 status plays a key
role in the treatment decision making process of early
breast cancer (BC).HER2 status is routinely assessed by
immunohistochemistry and/or in situ hybridization (ISH),
according to ASCO/CAP 2018 guidelines. The dichotomous
definition of HER2+ versus HER2- disease does
not reflect the spectrum of variable levels of HER2 protein
expression. We have analyzed the clinical outcomes
of a cohort of BC patients treated with neoadjuvant chemotherapy
(NACT) according to HER2 score.
Patients and methods: We performed a retrospective
analysis of 483 women with early BC treated with NACT
from March 2002 to November 2018 at Modena Cancer
Center. Clinical and pathological characteristics of patients
and disease were collected and compared to HER2 score
by Pearson’s chi square test. The impact of HER2 status on
pathological complete response (pCR) was set according
to logistic regression model.
Results: According to HER2 score, patients were divided
in 5 groups: 79 (16,3%) of them in HER2 score0 group,
153 (31,7%) in HER2 score1+, 53 (11%) HER2 score2+/
ISH-, 43 (9%) score2+/ISH+ and 155 (32%) score3+. Of
note, 59% of women had hormone receptor positive BC.
Overall, the HER2 status significant correlated to histotype
(p=0,003), grading (p=0,026) and pCR (p=0,0001).
The pCR was achieved in 132 (27%) patients: 46 (9,5%) in
HER2 score0/1+ group, 9 (1,9%) in HER2 score2+/ISH-,
8 (1,7%) in HER2 score2+/ISH+ and 69 (14,3%) in
HER2 score3+. The pCR rate was not statistically different
when both HER2 score0/1+ and HER2 score2+/ISHgroups
were compared to HER2 score2+/ISH+ one.
Considering HER2+ BCs, the pCR rate was significantly
higher in HER2 score3+ compared to HER2 score2+/
ISH+ (p=0,002). No statistically significant differences in
terms of RFS and OS inter-subgroups were observed.
Conclusions: The HER2 protein expression levels better
correlated to pCR compare to HER2 gene amplification. In
particular, the lack of difference in pCR rate between HER2 score2+/ISH+ and HER2 score2+/ISH– groups
may suggests a paradigm shift in the current classification
of HER2 status, consistently with emerging data on “HER2
low” BC landscape
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