185,270 research outputs found
Irvine, R, WX4434
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/394500Surname: IRVINE. Given Name(s) or Initials: R. Military Service Number or Last Known Location: WX4434. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 38595.217769
Item: [2016.0049.26793] "Irvine, R, WX4434
Irvine, A R, 421277
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/394485Surname: IRVINE. Given Name(s) or Initials: A R. Military Service Number or Last Known Location: 421277. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 57265.217754
Item: [2016.0049.26778] "Irvine, A R, 421277
Students in front of Mesa Court housing, UC Irvine
No full textThis group of photos is a series of shots of fifteen or so happy smiling UCI students standing on the stairs in front of Mesa Court housing. Some are waving their hands in a few shots.Handwritten on sheet: "6/4/68 Mesa Court R/AS, R/A"University of California, Irvine. University Communication
Inositides and the nucleus and inositides in the nucleus
No full textAlthough there are many forms of evidence linking phosphoinositides to nuclear function, the substance of the links remains largely undefined. One link between inositide metabolism and the nucleus is suggested by the implication of inositol trisphosphate (IP3) in the process of nuclear envelope reassembly (Sullivan et al., 1993). That paper will be discussed below in its context, but this review will principally focus on another nuclear-inositide connection - a potential inositide cycle in the nucleus. It comes as something of a shock to see data that point to a phosphoinositide cycle entirely separate from the familiar one in the plasma membrane. Again contrary to expectation, the data suggest that the cycle is not in the nuclear membrane but appears to be within the nucleus. This aspect of inositide function has profound implications for the role of inositides in cell division and growth. For example, it makes us rethink the tumor-promoting actions of phorbol esters and the teratogenic effects of Li÷ that have been associated with inositide homeostasis. In this article the evidence of a nuclear inositide cycle and what is known about its control are reviewed, and the role it may play in eukaryotic cell function is discussed. For a discussion of proposed nuclear functions for protein kinase C and what little is known about nuclear Ca2÷, the reader is referred to a more comprehensive recent review (Irvine and Divecha, 1992)
Nuclear diacylglycerol is increased during cell proliferation in vivo
No full textHighly purified nuclei were prepared from livers and kidneys of rats undergoing compensatory hepatic or renal growth, the former being predominantly by cellular proliferation, and the latter mostly by cellular enlargement. In liver, an increase in nuclear diacylglycerol (DAG) concentration occurred between 16 and 30 h, peaking at around 20 h. At the peak of nuclear DAG production a specific translocation of protein kinase C to the nucleus could be detected; no such changes occurred in kidney. There was no detectable change in whole-cell DAG levels in liver, and the increase in DAG was only measurable in nuclei freed of their nuclear membrane. Overall, these results suggest that there is a stimulation of intranuclear DAG production, possibly through the activation of an inositide cycle [Divecha, Banfic and Irvine (1991) EMBO J. 10, 3207-3214] during cell proliferation in vivo
Irvine, Jennie F.
No full textJohn R. Irvine - husbandhttps://stars.library.ucf.edu/cfm-ch-memoranda-1924/1119/thumbnail.jp
Highway Mortality of Mule Deer and White-tailed Deer
No full textDiscussed within this report is the current knowledge of deer-vehicle accidents and the solutions that have been tried. The author has discussed and given possible solutions and final recommendations to the current literature. From this literature the Grand Forks area was accessed and the best possible solution for the lowest cost was recommended to produce a workable study plan for the area.Includes bibliographical references.
Student paper submitted for Wildland Recreation
Assembly language for x86 processors / Kip R. Irvine, Florida International University, School of Computing and Information Sciences
No full textIncludes indexxxxi, 680 pages
Nuclear targeting of the beta isoform of type II phosphatidylinositol phosphate kinase (phosphatidylinositol 5-phosphate 4-kinase) by its alpha-helix 7
No full textType II phosphatidylinositol phosphate kinases (PIPkins) have recently been found to be primarily phosphatidylinositol 5-phosphate 4-kinases, and their physiological role remains unclear. We have previously shown that a Type II PIPkin [isoform(s) unknown], is localized partly in the nucleus [Divecha, Rhee, Letcher and Irvine (1993) Biochem. J. 289, 617-620], and here we show, by transfection of HeLa cells with green-fluorescent-protein-tagged Type II PIPkins, that this is likely to be the Type IIbeta isoform. Type IIbeta PIPkin has no obvious nuclear localization sequence, and a detailed analysis of the localization of chimaeras and mutants of the alpha (cytosolic) and beta PIPkins shows that the nuclear localization requires the presence of a 17-amino-acid length of alpha-helix (alpha-helix 7) that is specific to the beta isoform, and that this helix must be present in its entirety, with a precise orientation. This resembles the nuclear targeting of the HIV protein Vpr, and Type IIbeta PIPkin is apparently therefore the first example of a eukaryotic protein that uses the same mechanism
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