117 research outputs found
Characteristics for Software Optimization Projects
Get PDFThe increasing of the software systems complexity imposes the identification and implementation of some methods and techniques in order to manage it. The software optimization project is a way in which the software complexity is controlled. The software optimization project must face to the organization need to earn profit. The software optimization project is an integrated part of the application cycle because share same resources, depends on other stages and influences next phases. The optimization project has some particularities because it works on an finished product around its quality. The process is quality and performance oriented and it assumes that the product life cycle is almost finished.optimization, software, project management, quality, performance
Oral coenzyme Q10 supplementation does not prevent cardiac alterations during a high altitude trek to Everest base camp
No full textAbstract Holloway, Cameron J., Andrew J. Murray, Kay Mitchell, Daniel S. Martin, Andrew W. Johnson, Lowri E. Cochlin, Ion Codreanu, Sundeep Dhillon, George W. Rodway, Tom Ashmore, Denny Z.H. Levett, Stefan Neubauer, Hugh E. Montgomery, Michael P.W. Grocott, and Kieran Clarke, on behalf of the Caudwell Xtreme Everest 2009 Investigators. Oral Coenzyme Q supplementation does not prevent cardiac alterations during a high altitude trek to Everest Base Camp. High Alt Med Biol 15:000-000, 2014.-Exposure to high altitude is associated with sustained, but reversible, changes in cardiac mass, diastolic function, and high-energy phosphate metabolism. Whilst the underlying mechanisms remain elusive, tissue hypoxia increases generation of reactive oxygen species (ROS), which can stabilize hypoxia-inducible factor (HIF) transcription factors, bringing about transcriptional changes that suppress oxidative phosphorylation and activate autophagy. We therefore investigated whether oral supplementation with an antioxidant, Coenzyme Q10, prevented the cardiac perturbations associated with altitude exposure. Twenty-three volunteers (10 male, 13 female, 46±3 years) were recruited from the 2009 Caudwell Xtreme Everest Research Treks and studied before, and within 48?h of return from, a 17-day trek to Everest Base Camp, with subjects receiving either no intervention (controls) or 300?mg Coenzyme Q10 per day throughout altitude exposure. Cardiac magnetic resonance imaging and echocardiography were used to assess cardiac morphology and function. Following altitude exposure, body mass fell by 3?kg in all subjects (p<0.001), associated with a loss of body fat and a fall in BMI. Post-trek, left ventricular mass had decreased by 11% in controls (p<0.05) and by 16% in Coenzyme Q10-treated subjects (p<0.001), whereas mitral inflow E/A had decreased by 18% in controls (p<0.05) and by 21% in Coenzyme Q10-treated subjects (p<0.05). Coenzyme Q10 supplementation did not, therefore, prevent the loss of left ventricular mass or change in diastolic function that occurred following a trek to Everest Base Cam
Chasing the reflected wave back into the heart: a new hypothesis while the jury is still out
No full textELEMENTE DEGRADATE ALE PEISAJELOR TEHNOGENE DIN MUNICIPIUL CHIȘINĂU
Get PDFÎn timp și spațiu obiectivele tehnogene (industriale) suportă, sub impactul factorului antropic, modificări cantitative și calitative (ale aspectului, structurii, funcțiilor etc.). Astfel, sub acțiunea necontrolată a autorităților locale unele elemente tehnogene ajung în declin, sunt degradate, ruiniforme, abandonate etc. Aspectul acestor elemente creează o imagine și o senzație repulsivă. În lucrare sunt expuse unele elemente tehnogene degradate, abandonate, prezente în zonele industriale ale municipiului Chișinău. Selectarea acestor elemente degradate ale peisajelor tehnogene a fost realizată în conformitate cu tipologizarea peisajelor culturale (Cocean, David, 2014), după următoarele criterii: criteriul genetic și criteriul gradului de atractivitate
Comprehensive Assessment of Left Ventricular Wall Motion Abnormalities in Coronary Artery Disease Using Cardiac Magnetic Resonance
No full textAudit of radiology reports of patients with neoplasms performed on computed tomography
Get PDFBackground: Evaluation of the peculiarities of radiology reports of patients with neoplasms of the abdomen and pelvis to optimize clinical imaging
management.
Material and methods: The study included 104 patients, divided into two groups, experimental group (L2) and control group (L1), repeatedly investigated
by computed tomography in 2009-2019, a total of 440 examinations, of which 120 prospective examinations and 320 retrospective examinations, aged
between 25 and 85 years, with primary tumors of the abdomen and pelvis.
Results: Four specific descriptive criteria were analyzed from radiology reports and were obtained the following results: specification of the scanning
protocols in radiology reports (0% for L1 and 95.3% for L2), specifying the reason for the examination in radiology reports (100% for L1 and 26.0% for L2),
use of international terminology in radiology reports (0% for L1 and 74% for L2), patient follow-up in radiology reports (88.5% for L1 and 59.8 % for L2).
Conclusions: Following the SWOT analysis of the radiology reports, has been developed a standardized model for describing CT images of patients
with oncological pathologies of the abdomen and pelvis. The decision-making process was built on Strengths, eliminating Weaknesses, exploiting
Opportunities and removing Threats
Evaluation of three dimensional segmental myocardial motion using cardiac magnetic resonance
Get PDFDepartment of Radiology and Imaging, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova, The IVth Congress of Radiology and Medical Imaging of the Republic of Moldova with international participation, Chisinau, May 31 – June 2, 2018Background: Cardiovascular disease is one of the leading causes of morbidity and mortality worldwide. Assessment of global and regional
cardiac wall motion represents an important part of the evaluation of cardiac disease and ventricular function. The study aims to provide
a brief overview of cardiovascular magnetic resonance techniques used for quantification of global and regional myocardial wall motion.
Content: Quantification of myocardial wall motion using various parameters such as radial, circumferential and longitudinal velocities,
strain and strain rate, torsion and torsion rate demonstrated a high sensitivity for revealing even subtle functional alterations in myocardial
wall motion and holds great potential for detecting a variety of cardiac diseases in their early stage. The presentation discusses commonly
used techniques for this purpose such as myocardial tagging by magnetization saturation, strain encoded (SENC) imaging, phase-contrast
velocity encoding (VENC) or tissue phase mapping, displacement-encoding with stimulated echoes (DENSE) and 3D cine DENSE tissue
tracking methods, etc. The underlying principles of each technique, main advantages and disadvantages as well as their potential clinical
applications are also discussed.
Conclusions: Recent advances in cardiovascular magnetic resonance have allowed the development of a variety of techniques for accurate
quantification of global and regional myocardial wall motion that can facilitate the diagnosis and management of cardiac diseases
Unele referințe legislative privind protecția mediului din bazinul râului Bâc
No full textÎn articol sunt reflectate unele analize a legislației de mediu din Republica Moldova, a unor ordonanțe și hotărâri de guvern în raport cu starea factorilor de mediu din bazinele hidrografice. Studiul este realizat în contextul derulării primei etape de cercetare din cadrul proiectului institutional „Modificări și tendințe spațio-temporale ale componentelor de mediu din bazinul hidrografic Bâc sub impactul antropic”. Scopul cercetării expus în acest material este de a evidenția cerințele documentelor legislative și măsura în care corespund activitățile economice și de protecție a mediului din azinul râului Bâc
Low-Dose Computed Tomography: Could It be Applied for Secondary Prevention in Patients Undergoing Resection for Lung Cancer?
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