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Differential modulation of inhibitory synaptic transmission by compartmentalized synthesis of neurosteroids in the dorsal horn of the spinal cord
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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Modulation différentielle de la transmission synaptique inhibitrice par la synthèse localisée de neurostéroïdes dans la corne dorsale de la moelle épinière de rat
No full textSTRASBOURG-Sc. et Techniques (674822102) / SudocSudocFranceF
Modulation différentielle de la transmission synaptique inhibitrice par la synthèse localisée de neurostéroïdes dans la corne dorsale de la moelle épinière de rat
No full textNous avons tout d’abord caractérisé et comparé les propriétés de la transmission synaptique inhibitrice dans les laminae II et III-IV de la corne dorsale (CD) de la moelle épinière, qui sont impliquées dans le traitement des informations sensorielles. Nos résultats indiquent que la transmission synaptique glycinergique est prépondérante et que la cotransmission GABA/glycine est absente dans les laminae III-IV. Ensuite, nous avons étudié la possibilité d'un contrôle différentiel de la production de stéroïdes 35-réduits et ses conséquences sur la transmission GABAergiques dans les laminae II et III-IV. Nos résultats indiquent que la cinétique de déactivation des courants postsynaptiques inhibiteurs miniatures GABAergique est en grande partie contrôlée par les stéroïdes 35-réduits qui peuvent être synthétisés à partir de stéroïdes circulants et/ou localement par la modulation de l'activité de TSPO, notamment suite à une inflammation périphérique.First, we have characterised and compared the properties of inhibitory synaptic transmission in laminae II and III-IV of the dorsal horn (DH), which are involved in the processing of nociceptive and non-nociceptive sensory information. Our results indicate that inhibitory synaptic transmission in laminae III-IV is characterised by a dominant role of glycinergic inhibition and the absence of a functional GABA/glycine cotransmission. Second, we examined the possibility of a differential spatial control in the endogenous production of 35-reduced steroids and its consequences on GABAA receptor-mediated mIPSCs in laminae II and III-IV of the DH. Our results indicate that the decay kinetics of GABAA receptor-mediated mIPSCs in the DH of the spinal cord are largely controlled by 35-reduced steroids which can be produced from circulating steroid precursors and/or, in a spatially-restricted manner, by the modulation of the activity of TSPO, in particular by peripheral inflammation
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Modulation différentielle de la transmission synaptique inhibitrice par la synthèse localisée de neurostéroïdes dans la corne dorsale de la moelle épinière de rat
No full textSTRASBOURG-Sc. et Techniques (674822102) / SudocSudocFranceF
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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