543 research outputs found
Efficacy of dapagliflozin versus sitagliptin on cardiometabolic risk factors in Japanese patients with type 2 diabetes: A prospective, randomized study(DIVERSITY-CVR)
No full text主査 : 上芝元 / タイトル : Efficacy of dapagliflozin versus sitagliptin on cardiometabolic risk factors in Japanese patients with type 2 diabetes: A prospective, randomized study(DIVERSITY-CVR) /著者 : Ayako Fuchigami, Fumika Shigiyama, Toru Kitazawa, Yosuke Okada, Takamasa Ichijo, Mariko Higa, Toru Hiyoshi, Ikuo Inoue, Kaoru Iso, Hidenori Yoshii, Takahisa Hirose, Naoki Kumashiro /掲載誌 : Cardiovascular Diabetology /巻号・発行年等 : 19:1, 2020 /本文ファイル: 出版者
Protein large-scale motions revealed by quantum beams: A new era in understanding protein dynamics
No full textBiological systems function by constantly changing their hierarchical or inter-hierarchical interactions among molecules,
cells, and individuals. To visualize these dynamics, it is effective to approach them using penetrating quantum beams such as X-rays and neutron beams. Furthermore, the interpretation of the experimental results can be deepened by theoretical and computational techniques such as molecular dynamics simulations, which also complement phenomena hard to trace by experiments. For these issues, we have a symposium at the 60th Annual Meeting of the Biophysical Society of Japan held in September 2022 inviting 7 speakers, which is organized by Sekiguchi and Yamamoto. At the symposium, we will review recent advances in quantum beam techniques for biophysical research, mainly focusing on protein large conformational changes using X-ray (Sekiguchi, Yamamoto), neutron scattering (Matsuo), or a combination of both techniques (Inoue). We will also show theoretical studies that interpret or support experimental results (Kurisaki, Zhao) and a combination of experimental and theoretical studies (Hishikawa).journal articl
Present state of the development of the hyperlipidemia drug and ideal way of clinical trial.
No full textIsolation of Apolipoprotein E-Rich Very-Low-Density Lipoprotein from Human Plasma with Anti-Apolipoprotein B-100 Monoclonal Antibodies
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The effect of pravastatin, bezafibrate and cholexamine in a non-obese boundary-type diabetic with the hyperlipidemia on glucose tolerance.The change of blood sugar at 75gOGTT, insulin, C-peptide/insulin ratio, free fatty acid.
No full textCLINICAL EXPERIENCES OF HACHIMIJIOGAN IN THE UROGENITAL DISEASES
No full textUsing Hachimijiogan for the treatment of disease of the bladder neck such as prostatic hypertrophy and impotence, its effectiveness in relieving and reducing their subjective symptoms and the amount of residual urine was tested clinically. Effectiveness of Hachimijiogan for each of the following disorders was prostatic hypertrophy 81.5%, bladder neck sclerosis 60.0%, chronic prostatitis 72.7%, and impotence 33.3%. As for the relief of symptoms, Hachimijiogan showed significant effect on micturating pain and perineal pain. It was also effective for the improvement of protracted micturition and daytime frequent micturition and for the relief of residual urine and nocturnal frequent micturition. Hachimijiogan does not seem to have any severe side effects and it can be said to have shown satisfactory results for each of the disorders tested
[Articles] The Integral regional division of Ukraine and its composing regions
No full text本稿は平成27年度に京都大学大学院人間・環境学研究科に提出した修士論文の内容を一部修正したものである。At first, compares some social-economic regional divisions of Ukraine and by analyzing this, it is obvious that in six regions exists strong commonality. In the next unit, determining oblast as a unit, the author does regional division by each items, in other words by physical, demographical, natural-resource, industrial, and linguistic, using thematic maps in the atlas or statistics. Six cities are determined as a core city, in which lives more than 500 thousand people. Then overlays five color maps, what have same transparency, and finds commonality of oblasts by similarity of color. As a result, Ukraine is divided by six regions: Western, Central, Southern, South-eastern, North-eastern, and Eastern regions. Western region is composed by three subregions. Next the author writes about every divided region, and mentions about relationship with big regions or Ukraine. Finally, it is obvious that in Ukraine exist some various regions, not only two regions, and in this area exists the comparison of strong common periphery and not-integrated center. Future issues are analyzing place names of big regions in Ukraine, and comprehending formulation process of Ukrainian regions
Conversion of Light Propagation Direction for Highly Efficient Solar Cells
No full textOptical absorption coefficients are generally inherent to materials and are reduced for longer optical wavelengths, especially below their absorption edges. In tandem solar cells this makes thicker bottom cells necessary to improve their optical absorption efficiencies for longer optical wavelengths. This paper proposes a method to convert the propagation direction of an incident light toward the one parallel to optical absorption layers. High-efficiency optical absorption is demonstrated with thin absorption layers with this method. Drastic reduction of layer thicknesses necessary for high photoelectric conversion efficiencies will reduce the cost and improve the yield of various solar cells
Aromatic retinoid Ro 40-8757 reduces immunotoxicities of cyclophosphamide as revealed by immunohistochemical staining of lymphoid tissues and general pathologic examinations.
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