207 research outputs found

    First clinical experience of the looped Inoue balloon technique for antegrade percutaneous balloon aortic valvuloplasty.

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    Balloon aortic valvuloplasty (BAV) has played a limited role in the management of patients with severe aortic stenosis. However, BAV is being performed more frequently these days with the emergence of transcatheter aortic valve implantation (TAVI). We previously described a technique named "looped Inoue balloon technique" to simplify the antegrade transvenous BAV by making a loop in the left atrium using two stylets. We present a case in which the looped Inoue balloon technique was successfully applied. The patient was an 83-year-old woman with progressive dyspnea due to severe aortic stenosis. The aortic valve area was 0.39 cm(2) with a mean transvalvular gradient of 46 mmHg. The patient was deemed high risk for surgical aortic valve replacement or TAVI in view of the multiple comorbidities and frailty. Antegrade BAV using the looped Inoue balloon technique was performed. The procedure was successful without any complications. The post procedural aortic valve area increased to 1.15 cm(2) with a mean pressure gradient of 23 mmHg. This is the first report of clinical use of the looped Inoue balloon technique for antegrade BAV

    Nickel-Catalyzed Electrophilic Amination of the Biphenylene C-C σ-Bond

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    Inoue T., Nishino S., Yasui K., et al. Nickel-Catalyzed Electrophilic Amination of the Biphenylene C-C σ-Bond. Organic Letters 26, 4268 (2024); https://doi.org/10.1021/acs.orglett.4c01226.A nickel-catalyzed three-component carboamination of the biphenylene C-C σ-bond has been developed. Arylboronates and hydroxylamine derivatives work as carbon nucleophiles and nitrogen electrophiles, respectively, and the corresponding difunctionalized ring-opening products are obtained in good yields. The arylboronate nucleophile can be replaced with B₂pin₂ (boron nucleophile) and H-Si(OMe)₃ (hydride nucleophile), thus allowing for the aminoboration and hydroamination of the biphenylene C-C σ-bond under similar nickel catalysis

    コンパクトな集合表現によるマルチキャスト経路制御の効率化について

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    ERATO 湊離散構造処理系プロジェクト春のワークショップ(キックオフシンポジウム). 2010年5月28日(金)~29日(土). ERATO湊プロジェクト研究室

    Reliability Analysis for Disjoint Paths

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    Weakly nonlinear waves radiated by pulsations of a cylinder

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    A cylindrical sound wave is radiated into an unbounded ideal gas by an infinite circular cylinder that executes a sinusoidal pulsation uniformly along its axis with small amplitude and moderate frequency for only one period. In the leading order of approximation, the weakly nonlinear propagation of the wave is studied for the case of sufficiently large acoustic Reynolds number up to the stage that its profile develops into a cylindrical N wave with a tail. In the near field, solving the linear wave equation gives the near-field solution, which has a tail following the body part of the wave. The tail of the velocity profile decreases asymptotically in proportion to t*-⁴ as t* → ∞ at a fixed point in the near field and to t*-5/2 at a fixed point in the far field (t* is the time from the beginning of the pulsation). The tail vanishes in a high frequency limit with an acoustic Mach number being fixed. In the far field, an exact solution, which matches with the near-field solution, is obtained for a far-field equation by the method of strained coordinates. The evolution of the two shocks and the tail are then examined by making use of the equal-areas rule. At large distances from the cylinder, the whole profile of the wave approaches to an N wave with a long tail
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