3,955 research outputs found

    Letter from Gerald Masahiro Sato, attorney at law, World Trade Center, JABA Board Members, May 6, 1982

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    Letter from Gerald Masahiro Sato, attorney at law, World Trade Center, to the Japanese American Board Association (JABA) board members, about endorsing the National Coalition for Redress/Reparations (NCRR).The Jim Matsuoka Nikkei for Civil Rights and Redress Collection includes brochures, meeting notes and agendas, publications, booklets, and other material related to the Nikkei for Civil Rights and Redress (NCRR), formally known as the National Coalition for Redress/Reparations. The National Coalition for Redress/Reparations was officially formed on July 12, 1980, and included members of the Los Angeles Community Coalition for Redress/Reparations (LACCRR), Japanese Community Progressive Alliance (JCPA), Tule Lake Committee, Nihonmachi Outreach Committee, the Asian/Pacific Student Union, and other members of the community. The material was collected by Jim Matsuoka, a founding member of the organization. Matsuoka also served on the board and was the treasurer. In addition to the NCRR material, the collection also contains event flyers and Day of Remembrance material. For issues of the Nikkei for Civil Rights and Redress newsletter "Banner" published after 2007, visit the NCRR website at https://ncrr-la.org/

    Universal effects of solvent species on the stabilized structure of a protein

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    We investigate the effects of solvent specificities on the stability of the native structure (NS) of a protein on the basis of our free-energy function (FEF). We use CPB-bromodomain (CBP-BD) and apoplastocyanin (apoPC) as representatives of the protein universe and water, methanol, ethanol, and cyclohexane as solvents. The NSs of CBP-BD and apoPC consist of 66% α-helices and of 35% β-sheets and 4% α-helices, respectively. In order to assess the structural stability of a given protein immersed in each solvent, we contrast the FEF of its NS against that of a number of artificially created, misfolded decoys possessing the same amino-acid sequence but significantly different topology and α-helix and β-sheet contents. In the FEF, we compute the solvation entropy using the morphometric approach combined with the integral equation theories, and the change in electrostatic (ES) energy upon the folding is obtained by an explicit atomistic but simplified calculation. The ES energy change is represented by the break of protein-solvent hydrogen bonds (HBs), formation of protein intramolecular HBs, and recovery of solvent-solvent HBs. Protein-solvent and solvent-solvent HBs are absent in cyclohexane. We are thus able to separately evaluate the contributions to the structural stability from the entropic and energetic components. We find that for both CBP-BD and apoPC, the energetic component dominates in methanol, ethanol, and cyclohexane, with the most stable structures in these solvents sharing the same characteristics described as an association of α-helices. In particular, those in the two alcohols are identical. In water, the entropic component is as strong as or even stronger than the energetic one, with a large gain of translational, configurational entropy of water becoming crucially important so that the relative contents of α-helix and β-sheet and the content of total secondary structures are carefully selected to achieve sufficiently close packing of side chains. If the energetic component is excluded for a protein in water, the priority is given to closest side-chain packing, giving rise to the formation of a structure with very low α-helix and β-sheet contents. Our analysis, which requires minimal computational effort, can be applied to any protein immersed in any solvent and provides robust predictions that are quite consistent with the experimental observations for proteins in different solvent environments, thus paving the way toward a more detailed understanding of the folding process

    Local Tunneling Barrier Height on Si(111) Reconstructed Surfaces

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    The family name of the last author should read Masahiro Miyao </jats:p

    _3R_Supplementary – Supplemental material for Discrepancies between patients’ and pharmacists’ perceptions of the role of community pharmacists as advisors on the use of pharmaceuticals in Japan: A comparison prior to and following revision of the Pharmacists’ Act

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    Supplemental material, _3R_Supplementary for Discrepancies between patients’ and pharmacists’ perceptions of the role of community pharmacists as advisors on the use of pharmaceuticals in Japan: A comparison prior to and following revision of the Pharmacists’ Act by Shinji Oshima, Mari Yamagishi, Mitsuyoshi Okita, Hayato Akimoto, Akio Negishi, Norimitsu Horii, Mizue Mutoh, Yasuko Sannomaru, Sachihiko Numajiri, Naoko Inoue, Shigeru Ohshima, Masahiro Wada and Daisuke Kobayashi in SAGE Open Medicine</p

    yiyi1991/source_data_deposit_feasibility: source_data_deposit_feasibility

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    &lt;p&gt;The data and code for the research article &quot;Perceived feasibility of a net-zero system transition and its potential barriers among Japanese experts&quot;. The research is conducted by Yiyi Ju, Masahiro Sugiyama, and Hiroto Shiraki.&lt;/p&gt; &lt;p&gt;Data availability The anonymized data in the research article can be found in this repository. This will enable the reproduction of key figures. Anonymized data is available upon reasonable request.&lt;/p&gt; &lt;p&gt;Code availability The code for analysis and visualization in the research article can be found in this repository. This will enable the reproduction of key figures (but not all including the supplemental figures, considering of the privacy, e.g., specific information, such as working experience, research field, and whether or not the person is an IPCC author, can help identify specific experts).&lt;/p&gt

    Impact of omission/reduction of vincristine from R-CHOP in treatment of DLBCL

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    博士(医学) 乙第3118号(主論文の要旨、要約、審査結果の要旨、本文),著者名:Shoko MARSHALL, Noriko NISHIMURA, Norihito INOUE, Hirofumi YAMAUCHI, Naoko TSUYAMA, Kengo TAKEUCHI, Yuko MISHIMA, Masahiro YOKOYAMA, Toshie OGASAWARA, Naoki MORI, Tetsuya OGAWA, Hiroshi SAKURA, Yasuhito TERUI,タイトル:Impact of Omission/Reduction of Vincristine From R-CHOP in Treatment of DLBCL,掲載誌:Clinical lymphoma, myeloma & leukemia(2152-2669),巻・頁・年:21巻3号 p.162~169(2021),著作権関連情報© 2020 The Author(s).,DOI:10.1016/j.clml.2020.12.01

    NICHIBUNKEN NEWSLETTER ; 10

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    Gorbachev's Visit to Japan (April 1991) : Achievements and Disappointments / KIMURA Hiroshi Wrestling on American TV / MORIOKA Masahiro Instituto Español de Japonologia's Inaugural Symposium / Maria D. RODRIGUEZ del ALISAL Academic Activities AKAMATSU Keisuke, Hijōmin no Seiminzoku (The Sexual Customs of the Uncommon People) / INOUE Shoichi Kōno Taeko, Miiratori Ryokitan (The Bizarre Tale of a Reversal) / SUZUKI Sadami Center News From the Editor / SATO Tomomiothe

    Buffer-gas pressure broadening for the (0 00 3) ← (0 00 0) band of N2O measured with continuous-wave cavity ring-down spectroscopy

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    Buffer-gas pressure broadening for the (0 00 3) ← (0 00 0) band of N2O was investigated with continuous-wave cavity ring-down spectroscopy within the temperature range of 243–353 K. The measured absorption profiles were analyzed with Voigt functions. The pressure broadening coefficients, γ(gas), and the temperature dependent parameters (broadening exponent) were determined for a variety of buffer gases: N2, O2, He, Ne, Ar, Kr, and Xe. γ(air) values were also determined using γ(N2) and γ(O2). The effective potential well depth for (N2O)2 under room temperature was estimated from γ(Ne, Ar, Kr, Xe) using the Permenter–Seaver’s model, and the results were compared with theoretical calculations. Simultaneously, the effective potential well depth for (CO2)2 is discussed.PublishedTomoki Nakayama, Hisato Fukuda, Akihiro Sugita, Satoshi Hashimoto, Masahiro Kawasaki, Simone Aloisio, Isamu Morino, Gen Inoue, Buffer-gas pressure broadening for the (0 00 3) &lt;-- (0 00 0) band of N2O measured with continuous-wave cavity ring-down spectroscopy, Chemical Physics, Volume 334, Issues 1-3, 20 April 2007, Pages 196-203.https://doi.org/10.1016/j.chemphys.2007.03.0010301-010
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