1,721,168 research outputs found
ROLE OF PET/CT IN RADIOTHERAPY TREATMENT PLANNING
No full textThis chapter focuses on the rationale, target validation, dose prescription verification and evaluation, and recent clinical achievements in the field of integrating positron emission tomography imaging into radiotherapy treatment planning. Application of functional imaging to radiotherapy is a rapidly expanding field with the development of new modalities and techniques. Functional imaging of positron emission tomography in conjunction with radiotherapy provides new avenues toward the clinical application of dose painting as a new radiotherapy strategy delivering optimized dose redistribution according to the functional imaging information to further improve tumor control. New biological imaging methodologies mainly based on positron emission tomography/computed tomography, magnetic resonance imaging, and magnetic resonance spectroscopy imaging, in conjunction with radiotherapy, make dose painting possible. It can be used to draw a three-dimensional map of radiobiological relevant parameters as its inherent potential to trace the real target volume, consisting of tumor cells that require a therapeutic dose to control the disease. Positron emission tomography/computed tomography is outstanding and widely used in daily clinical practice. It offers molecular biological information on the tumor microenvironment in addition to anatomical imaging and shows significant biological heterogeneity of tumors, such as metabolism, proliferation, hypoxia, radioresistance cell density, and perfusion
DETECTION OF BONE METASTASES AND EVALUATION OF THERAPY RESPONSE IN PROSTATE CANCER PATIENTS BY RADIOLABELLED CHOLINE PET/CT
No full text
Le developpement moteur et cognitif du grande pramature dans le prèmiere année de vie
No full textNo abstrac
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
PET/MRI in gynecological tumors
No full textThe diagnostic approach to gynecological tumors includes anatomical and molecular imaging methods, representing a strong support for clinicians to define tumor extension, to plan the best treatment strategy and patient management. The possibility of combining morphological and functional information in a single examination, using hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) technique, represents a very promising tool in the different settings of gynaecologic tumors. In the present review, the current literature and potential clinical applications of PET/MRI in the most common types of gynecological tumors are discussed. The role of PET/MRI is in staging, restaging and after treatment of gynecological tumors is presented, focusing on cervical, endometrial and ovarian cancer. Moreover, the diagnostic accuracy of PET/MRI and the correlation between quantitative parameters (standardized uptake value and apparent diffusion coefficient) of PET/MRI hybrid systems are briefly reviewed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Detection of Bone Metastases and Evaluation of Therapy Response in Prostate Cancer Patients by Radiolabelled Choline PET/CT
No full textBone is the most common site for metastases in human prostate cancer patients. Skeletal metastases are a significant cause of morbidity and mortality and overall greatly affect the quality of life of patients. A significant portion of patients may be treated with curative intent when micrometastatic disease is present and not detected on current imaging studies, including bone scan and computed tomography scan. Molecular imaging approaches and, in particular Choline positron emission tomography, have been investigated to improve the detection of metastatic disease in patients with prostate cancer
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
