1,721,052 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Gene expression and DNA variation analysis of sacs to identify the pathophysiology of indirect inguinal hernia
No full textİndirekt İnguinal Herni (İİH), fetal dönemde testisin skrotuma inişi esnasında oluşan processus vaginalisin testisin inişinin tamamlanmasından sonra oblitere olmaması sebebiyle açık kalan PV’ye batın içi organların dolması sonucu oluşur ve tedavi edilmediği durumlarda doku, organ kaybı ve hayati tehlike oluşturma ihtimali vardır. İİH multifaktöryel bir hastalıktır ve PV obliterasyonunda farklı genetik yolaklar rol almaktadır. Trakya Üniversitesi Çocuk Cerrahisi kliniğinde İİH etyolojisini araştırmak amacıyla ameliyat olan 20 erkek İİH ve 20 sünnet hastasından elde edilen doku örneklerinde GATA6 ve TBX3 gen ekspresyonları, ve SNP analizleri yapıldı. Genetik değerlendirmede, İİH grubunda GATA6 ekspresyonu artmış (p<0.001), TBX3 ekspresyonu azalmış (p<0.001) olarak bulundu. Ancak genotiplendirme analizinde herhangi bir polimorfizme rastlanmadı. Apoptozun, İİH grubundaki artmış GATA6 ekspresyon düzeylerine rağmen gerçekleşmemiş olması PPV’lerde GATA6-Bax etkileşiminin immünohistokimyasal olarak araştırılması gerektiği sonuncunu doğurmakta, azalmış TBX3 ekspresyon düzeylerinin TGF-?1 ve WNT yolakları üzerinden apoptozu düzenlemesi sebebiyle GATA6 ile birlikte etkileşiminin ileri düzeyde araştırılması gerektiği kanısına varılmıştır. Çalışmanın sonuçlarına göre, apoptotik yolakta GATA6 ve TBX3 aracılı basamaklarda mevcut bir patolojinin İİH gelişimine neden olabileceği söylenebilir. Bununla birlikte daha fazla sayıda hasta ile ya da hayvan çalışması ve doku kültürü gibi yöntemler aracılığıyla, apoptotik yolakta rol alan diğer genlerin de çalışıldığı daha geniş kapsamlı çalışmalara ihtiyaç olduğu ve bu çalışmaların İİH etiyolojisini aydınlatmada faydalı olacağı düşüncesindeyiz.Indirect Inguinal Hernia (IIH) occurs as a result of the filling of the abdominal organs into the open PV due to the fact that the processus vaginalis formed during the descent of the testicle to the scrotum during the fetal period is not obliterated. If left untreated, tissue or organ loss can occur and can be life-threatening. IIH is a multifactorial disease and different genetic pathways play a role in PV obliteration. To investigate the etiology of IIH, GATA6 and TBX3 gene expressions and SNP analyzes were performed in tissue samples obtained from 20 male IIH and 20 circumcised patients who were operated in Trakya University Pediatric Surgery Clinic. Expression of GATA6 increased (p<0.001) and TBX3 expression decreased (p<0.001) in IIH group. However, no polymorphism was found in the genotyping analysis. The absence of apoptosis despite the increased GATA6 expression levels in the IIH group suggests that the GATA6-Bax interaction in PPVs should be investigated immunohistochemically. It is concluded that the interaction with GATA6 should be investigated further, since decreased TBX3 expression levels regulate apoptosis through TGF-?1 and WNT pathways. According to the results of the study, it can be said that a pathology present in the GATA6 and TBX3-mediated steps in the apoptotic pathway may cause the development of IIH. However, we believe that more comprehensive studies are needed to study more genes involved in the apoptotic pathway with more patients or through methods such as animal studies and tissue culture, and these studies will be useful in elucidating the etiology of IIH
The effects of methylene blue on the wound healing at the colonic resection-anastomosis modality in rats
No full textTıpta UzmanlıkBu çalışmada sıçanlarda oluşturulan kalın bağırsak rezeksiyon-anastomoz modelinde, metilen mavisinin doku iyileşmesi üzerine etkisini mekanik, biyokimyasal ve histopatolojik olarak değerlendirmek amaçlandı. Çalışmamızda her birinde 10'ar adet wistar albino sıçan bulunan üç grup oluşturuldu. Grup 1 (Sham) : Karın orta hat insizyonu yapılıp kapatıldı. Grup 2 (RA) : Karma orta hattan girilip, inen kolona rezeksiyon-anastomoz yapıldı. Grup 3 (RAM) : Grup 2'nin işlemlerine ek olarak intraperitoneal metilen mavisi verildi. Denekler cerrahi işlemden 8 gün sonra geri dönüşümsüz uyutuldu. Anastomoz hattını içeren barsak segmentlerinin patlama basıncı manometrik olarak ölçüldü. Daha sonra bu bölgedeki doku hidroksiprolin düzeyleri değerlendirildi. Histopatolojik incelemede doku iyileşmesi parametreleri olarak; tüm bağırsak katmanlardaki mukozal hasar, enflamatuar yanıt, kollajen birikimi, vaskülarizasyon ve çapraz bağ yapmış kollajen araştırıldı, istatistiksel değerlendirmeler Anova ve Ki-kare yöntemiyle yapıldı. Doku hidroksiprolin değerleri; Sham grubunda 5.46 ± 0.18, RA grubunda 2,66 ± 0,21, RAM grubunda 3,74 ± 0,23ug/mg yaş doku, manometrik olarak patlama basıncı değerleri; Sham grubunda 127,3 ± 4,39, RA grubunda 68,8 ± 2,61, RAM grubunda 88,6 ± 2,71 mm/Hg olarak bulundu. RAM grubunda tespit edilen hidroksiprolin seviyesi ve doku direncindeki artış istatistiksel olarak anlamlıydı (p<0.05). Histopatolojik incelemede RAM grubunda RA grubuna göre doku iyileşmesinin daha iyi olduğu tespit edildi. Bu çalışmada RAM grubunda istatistiksel olarak anlamlı bir direnç artışı ve iyileşme sürecinde de kalite artışı gözlendi. RAM grubunda kolonun tüm katmanlarında demetler 36yapan kollajen birikimi, RA grubuna göre belirgin olarak artmıştı. RA grubunda ise oluşan kollajen dokusu düzensiz, miktarı da histopatolojik ve biyokimyasal olarak beklenenden azdı. Metilen mavisinin rezeksiyon-anastomoz yapılan sıçanlarda bağırsakların iyileşme sürecini olumlu yönde etkilediği, doku direncini artırdığı kanısındayız. Metilen mavisi bu işlevini doku oksidazları için elektron kabul etmesi, moleküler oksijenin süper okside indirgenmesini inhibe etmesi ve nitrik oksidin hücre içindeki habercisi solubl cGMP'ın oluşumunu inhibe ederek oluşturmuş olabilir. Bu sonuçlar klinik olarak önemli ve metilen mavisinin lokal- sistemik etkilerinden dolayı olabilir. Anahtar Kelimeler: Metilen Mavisi; Anastomoz; Yara İyileşmesiThe aim of this study is to evaluate mechanical, histopathological and biochemical effects of methylene blue on the wound healing at the colonic resection-anastomosis modality in rats. In our study, three groups were formed and each group contains 10 Wistar albino rats. Group 1 (Sham group): Abdominal mid-line incision was performed and the incision was closed. Group 2 (RA group): After abdominal mid-line incision, resection-anastomosis of descending colon was performed Group 3 (RAM group): In addition Group 2, intraperitoneal methylene blue was given in this group. After 8 days of the surgical procedure, all rats were hipnotised irreversible. The burst pressure of colonic segments containing anastomosis line, was measured with manometric method and hydroxyprolin levels at this segments was evaluated. In histopathologycal examination mucosal damage, inflammatory answer, vascularisation and cross-linked collagen tissue of the all-colonic sides, were evaluated as tissue healing parameters. Anova and %2 tests were used to compare groups. Tissue hydroxypyroline levels were found out as follows, in sham group 5,46 ± 0,18, in RA group 2,66 ± 0,21, in RAM group 3,74 ± 0,23ug/lmg wet tissue. The burst pressure of 38derived from manometer were found oat as follows: in sham group 127,3 ± 4,39, in RA group 68,8 ± 2,61, in RAM group 88,6 ± 2,71 mmHg. Tissue hydroxypyroline and burst pressure was statistically higher in RAM group than RA group (p<0,05). On hystopathologycal evaluation was found that tissue healing in RAM group was better than RA group. We think that methylene blue positively affect colonic tissue healing enhanced tissue resistance in rats which were performed colonic resection and anastomosis. Cross linked collagen fibrills were increased all colonic layers of RAM group towards RA group. Collagen tissue at RA group were irreguler and lower unexpected as hystopathologycal and biochemical. Methylene blue may work in tissue healing by these ways as follows; receive electron for tissue oxidase, block molecular oxygen to superoxide reaction, block soluble cGMP formation that is messenger of nitric oxide. These results important as clinical and may become local-systemic effect due to methylene blue. Keywords: Methylene Blue; Anastomoses; Wound Healin
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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