104,603 research outputs found
SPECTROSCOPIC REMOTE-SENSING OF MOLECULAR CONSTITUENTS IN THE ATMOSPHERE BY LASER-RADAR TECHNIQUES BASED ON OPTICAL SCATTERING PHENOMENA
H. Inaba and T. Kobayasi, Nature, 224, 170, (1969). T. Kobayasi and H. Inaba, Appl. Phys. Letters, 17, 139, (1970). H. Inaba and T. Kobayasi. Invited paper to the Sixth International Quantum Electronics Conference, Kyoto, Japan, September 1970. T. Kobayasi and H. Inaba. Proceedings of IEEE., 58, 1568, (1970).""Author Institution: Research Institute of Electrical Communication, Tohoku UniversityThe usefulness of Raman spectroscopy, which is so far recognized as a complementary technique to infrared spectroscopy, can be extended to include various new fields which are unique to itself. The laser-Raman radar scheme detecting the Raman backscattered echoes has been and confirmed experimentally by the present , which is capable of measuring remotely the number density of molecular constituents as well as their species existing not only in the ordinary but also in the polluted atmosphere. This paper wishes to report the operational performance and the experimental results, so far obtained, of our laser-Raman radar as a completely single-ended system for the chemical analysis of the real atmosphere. An alternative method, which utilizes a frequency-tunable dye laser with high repetition rate of pulsed operation is also developed to investigate the resonance spectroscopic effects of a variety of molecules and atoms contained in the lower and upper atmosphere. These effects include the fluorescence and the resonance scatterings along with the resonance Raman scattering, and are expected to improve significantly the sensitivity and the range capability for the constituent analysis of our environmental air
The net reproduction rate and the type-reproduction number in multiregional demography
In order to study effects of migration on demographic changes of multiregional populations, multiregional population modelling is a useful traditional tool. Although multiregional mathematical demography has been extensively explored since the beginning of the 1970s, its key concept, the multiregional net reproduction rate, has been long neglected. In this review, we focus on a multiregional stable population system and elaborate the definition of the multiregional net reproduction rate. Next we introduce the type-reproduction number from mathematical epidemiology and show that it becomes a useful index to formulate a simple control relation for a multiregional population. Mathematical ideas presented here will help us to reconsider multiregional mathematical demography, which is a useful theoretical framework to study effects of interregional migration on population dynamics and composition.
Assessing clonality of Vibrio cholerae Inaba isolates by characterization of nonsense mutations in wbeT
The transferase gene wbeT of six clinical isolates of Vibrio cholerae O1 biotype El Tor was analysed. Two unique mutations were identified in the wbeT gene of three Inaba isolates. Due to their random nature, mutations in wbeT can be used to determine the clonal origin of clinical Inaba isolates
Correlation of structure and function in the oxidative phosphorylation system of submitochondrial particles
1. After the centrifugation of sonicated heavy beef heart mitochondria at 75, 000 × g for 10 minutes, the supernatant was centrifuged at 144, 000 × g for 30 minutes. The residue was revealed being composed of
vesicular inner membrane fragments (ETPH), about 600 to 1000 Å. in diameter, showing a morphological homogeneity and a high capacity of oxidative phosphorylation. 2. The Pia ratio of the ETPH in the presence of succinate and of NADH2 was 1.68 and 2.54, respectively, and the corrected Pia value for O2 gas equilibrium was 1. 01 and 1.40, respectively.
3. The capacity of oxidative phosphorylation in ETPH fraction was parallel to the activity of the oligomycin. sensitive ATPase in these fractions. 4. The P/0 ratio of ETPH was decreased to about 50 % by hypotonic
treatment. The decrease of P/0 ratio was restored to the level of about 90 % by incubating the ETPH with ATP and BSA. In the instance where the P/0 ratio was low level in the hypotonic medium, the surface structure of ETPH was observed as a swollen form and the head pieces
of the elementary particles were clearly observed in contrast to the solid surface structure of ETPH in the isotonic medium. 5. The P/0 ratio of ETPH was decreased to about 60 % by relatively severe sonication, and after separating the residue from the supernatant, that of the residue decreased further to about 40 %. The P/0 ratio of the residue was restored to the level before the separation on the addition of the supernatant containing oligomycin-insensitive ATPase. 6. A discussion was made on the correlation between the surface structure and the activities at terminal phosphorylation step of ETPH
after the simple physico-chemical treatment.</p
Periodic oscillatory activity in parahippocampal slices maintained in vitro
Brain slices maintained in vitro have been extensively used for studying neuronal synchronization. However, the validity of this approach may be questioned since pharmacological procedures are usually required to elicit spontaneous events similar to the EEG activity recorded in vivo. Here, we report that when superfused with control medium, rat brain slices comprising the entorhinal and perirhinal cortices along with a portion of the basolateral/lateral nuclei of the amygdala can synchronously generate periodic oscillatory activity at 5-11 Hz every 5-30 s. The periodic events: (i) correspond intracellularly to synaptic depolarizations in regularly firing neurons analyzed in the three areas; (ii) have no fixed site of onset; (iii) spread with time lags of 8-20 ms; and (iv) continue to occur asynchronously after their surgical isolation. NMDA receptor antagonism reduced the duration of the oscillatory events, while glutamatergic non-NMDA receptor antagonism abolished them. Activation of μ-opioid receptors, a procedure that hyperpolarizes interneurons thus decreasing GABA release, reversibly decreased the rate of occurrence of periodic oscillatory activity (POA). However, periodic events continued to occur during application of GABAA or GABA B receptor antagonists as well as in the presence of the cholinergic agent carbachol. We also found that POA was abolished by baclofen and irreversibly reduced by the gap junction decoupler carbenoxolone. These findings demonstrate that parahippocampal networks in a brain slice preparation can generate periodic, synchronous activity under quasi-physiological conditions. These network oscillations (i) reflect the activation of ionotropic glutamatergic and GABAergic receptors, (ii) are contributed by gap-junction interactions, and (iii) are controlled by GABAB receptors that are presumably located presynaptically. © 2005 Published by Elsevier Ltd on behalf of IBRO
Emergence of Vibrio cholerae O1 biotype El Tor serotype Inaba from the prevailing O1 Ogawa serotype strains in India
The toxigenic Inaba serotype of Vibrio cholerae O1 biotype El Tor reappeared in India in 1998 and 1999, almost 10 years after its last dominance in Calcutta in 1989. Extensive molecular characterization by ribotyping, restriction fragment length polymorphism, and pulsed-field gel electrophoresis indicated that recent Inaba strains are remarkably different from the earlier Inaba strains but are very similar to the prevailing V. choleraeO1 Ogawa El Tor biotype strains. The antibiograms of the Inaba strains were also similar to those of the recent V. cholerae Ogawa strains. These V. cholerae O1 Inaba strains appear to have evolved from the currently prevailing Ogawa strains and are likely to dominate in the coming years
Emergence of Vibrio cholerae O1 biotype El Tor serotype Inaba from the prevailing O1 Ogawa serotype strains in India
The toxigenic Inaba serotype of Vibrio cholerae O1 biotype El Tor reappeared in India in 1998 and 1999, almost 10 years after its last dominance in Calcutta in 1989. Extensive molecular characterization by ribotyping, restriction fragment length polymorphism, and pulsed-field gel electrophoresis indicated that recent Inaba strains are remarkably different from the earlier Inaba strains but are very similar to the prevailing V. choleraeO1 Ogawa El Tor biotype strains. The antibiograms of the Inaba strains were also similar to those of the recent V. cholerae Ogawa strains. These V. cholerae O1 Inaba strains appear to have evolved from the currently prevailing Ogawa strains and are likely to dominate in the coming years
Correlation between fold increase of Inaba OSP specific antibody responses and cumulative diarrheal volume.
X axis represents the fold-increase (day 10 to day 0) of IgM, IgA, and IgG responses against V. cholerae O1 Inaba OSP and Y axis represents cumulative diarrhea following experimental challenge with wild type V. cholerae O1 Inaba 10 or 90 days post vaccination with Inaba CVD 103-HgR. Dashed horizontal lines mark moderate (3L) or severe (5L) diarrheal values. Dashed vertical line denotes 1.5-fold anti-OSP antibody value change (day 10 post-vaccination compared to day 0 pre-vaccination).</p
MEASUREMENTS OF RAMAN CROSS SECTIONS FOR VARIOUS GASES IN THE POLLUTED ATMOSPHERE BY MEANS OF PULSED LASER-RAMAN AND PULSE-GATED PHOTON COUNTING METHODS
H. Inaba and T. Kobayasi, Nature 224, 170 (Oct. 1969) T. Kobayasi and H. Inaba, Appl. Phys. Letters 17, 139 (Aug. 1970); Proc. of the IEEE. 58, 1568 (1970). H. Inaba and T. Kobayasi, Paper presented to 26th Symposium on Molecular Structure and Spectroscopy N4, Columbus, Ohio, June 14-18, 1971. W. F. Murphy, W. Holzer and H. J. Bernstein, Appl. Spectroscopy 23, 211 (1969). D.G. Fouche and R.K. Chang, Appl. Phys. Letters 18, 579 (June 1971).""Author Institution: Research Institute of Electrical Communication, Tohoku UniversityFeasibility and potentiality of the laser radar system which detects the Raman-shifted backscattering, either in non-resonant or resonant nature, from chemical contents of atmospheric pollutants to identify and to monitor remotely their concentrations have been However, for the precise measurement of species concentration, the knowledge on the Raman scattering cross sections is always required. This paper presents the measured result and their comparison of the Raman cross sections of various molecules present in the atmosphere such as relative to that of as a reference gas. We employed primarily a molecular nitrogen laser with 10mW average power at 3371 {\AA}, 20 kW peak power of 10 nsec duration and a repetition rate of 50 Hz. Recently, we have succeeded in the operation of transverse excitation atmospheric (TEA) nitrogen laser at 3371 {\AA} which is applicable to the field-use and also to the laboratory experiments. The Raman scattered radiation was observed in a direction perpendicular to the linearly polarized plane of the incident laser beam. The signal was processed by the pulse-gated photon counting method synchronized with the repetitive laser pulse, which is valuable for detecting extremely weak light signals. The accuracy of our measured cross sections is within 10\% and their values were found to agree well with the pre-laser result by Murphy et and the laser result by Fouche et for several gases. It is noteworthy that band has 15 times and band has 7.2 times larger cross section than that of , due possibly to resonance Raman effect at 3371 {\AA}
Letter, [Author unclear] to Paulina T. Merritt
Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
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