296 research outputs found
Challenges and Considerations in Assessing GERD: A Critical Review of a Study in Southern Punjab, Pakistan [Response to Letter]
No full textMuhammad Fawad Rasool,1 Rimsha Sarwar,1 Muhammad Subhan Arshad,1,2 Imran Imran,3 Hamid Saeed,4 Abdul Majeed,1 Muqarrab Akbar,5 Muhammad Omer Chaudhry,6 Anees Ur Rehman,1 Waseem Ashraf,3 Tanveer Ahmad,7 Waleed Badoghaish,8 Faleh Alqahtani9 1Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan; 2Department of Pharmacy, Southern Punjab Institute of Health Sciences, Multan, 60000, Pakistan; 3Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan; 4University College of Pharmacy, Allama Iqbal Campus, University of the Punjab, Lahore, 54000, Pakistan; 5Department of Political Science, Bahauddin Zakariya University, Multan, 60800, Pakistan; 6School of Economics, Bahauddin Zakariya University, Multan, 60800, Pakistan; 7Institute for Advanced Biosciences (Iab), CNRS UMR5309, INSERM U1209, Grenoble Alpes University, La Tronche, 38700, France; 8Department of Internal Medicine, College of Medicine, University of Tabuk, Tabuk, 71411, Saudi Arabia; 9Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi ArabiaCorrespondence: Muhammad Fawad Rasool; Faleh Alqahtani, Email [email protected]; [email protected]
The Identification of Selective Pathogenic Microbial Community Biofilms in Different Distribution Pipeline Materials and Their Disinfection Kinetics
No full textBiofilms in water distribution lines strongly affect water safety as they are the main carriers of pathogens. The current study investigated the biofilm formation and identification of selected pathogens in different distribution pipeline materials and their disinfection method in an annular reactor (AR). Initially, the quality of the flowing water from each pipeline material was analyzed, i.e., pH, TDS, EC, turbidity, and salinity; then, the biofilm formation was monitored for each material, i.e., ABS, PC, PVC, PP, and HDPE. Further, the disinfection kinetics of biofilm at different chlorine doses, i.e., 0.5, 1.0, 1.5, and 2.0 mg/L, was investigated. The selected pathogens, i.e., E. coli, Pseudomonas, Shigella, Salmonella sp., and Vibrio sp. were identified in biofilms formed in different pipeline materials. The disinfection kinetics results showed that a chlorine dose of 2.0 mg/L was the most effective in disinfecting selected pathogens. Following the disinfection kinetics, it was observed that Salmonella sp. was disinfected within 7 days, whereas other pathogenic biofilms were disinfected within 14 days. The efficacy of chlorine disinfection was affected by the types of pipeline materials. The study outcomes could provide insights into biofilms' disinfection method and the selection of suitable pipeline materials to ensure drinking water safety
Photocatalytic Denitrification of Nitrate Using Fe-TiO2-Coated Clay Filters
No full textIn this work, 3D-structured clay filters were prepared and coated with iron-doped titanium dioxide (Fe-TiO2) using 3D printing and sol–gel soaking and calcination techniques. Three-dimensional printing was employed to mold and shape the clay filters before annealing. The coated and uncoated filters were characterized for different properties, i.e., morphology, optical properties, and crystalline structure, using field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDS), UV/Vis diffused reflectance spectroscopy (DRS), and X-ray diffraction (XRD). The FESEM images show uniform coatings of round-shaped Fe-TiO2 on the tiny pore of the clay filter. The optical energy band gap of the obtained coating was around 2.8 eV, estimated by Tauc’s plot, compared with 3.2 eV of pristine anatase TiO2. The XRD spectra data processed through XRD software revealed the coatings of TiO2 on the filter surface with the obtained phase of anatase. The photocatalytic performance of bare and coated filters was initially tested for the degradation of indigo carmine (IC) dye and the obtained results suggested the photocatalytic degradation of IC dye by the Fe-TiO2 clay filter compared with the bare filter. Afterward, the denitrification of nitrate NO3 at various concentrations was performed using Fe-TiO2-coated clay filters and analyzing the total nitrogen (TN) analysis and reduction of NO3 to nitrite (NO2−), nitrogen monoxide (NO), and nitrogen gas (N2). The TN analysis revealed up to 81% denitrification efficiency of the 30 ppm NO3 solution with the photocatalytic response of the Fe-TiO2-coated filter. The results revealed that the Fe-TiO2-coated clay filter has a high potential for denitrification applications under natural sunlight
Efficient and Rapid Combined Electrocoagulation–Filtration of Arsenic in Drinking Water
No full textArsenic (As) contamination is a severe problem in drinking-water sources. This study
designed and investigated a novel combined electrocoagulation–filtration (ECF) system to investigate
As treatment and filtration in drinking water in collaboration with HANDS-Pakistan and Medico
International, Germany. Two separate pilot-scale ECF systems were designed and developed with an
electrocoagulation (EC) unit and a commercially available PAUL® filter configured with vertical flatsheet ultra-low-pressure membranes of 0.04 μm pore size for the combined treatment and filtration
of different As concentrations. Real drinking water at different As concentrations, i.e., 100, 200, and
300 μg/L were tested on one ECF system with EC electrodes of iron (Fe) and another system with
aluminum (Al), at different treatment times (0, 5, 10, 20, 45, 60, 120, 180 min), at a fixed current density
(12 mA/cm2
) and water flow rate of 1 L/min. The initial results showed 99% As removal within
5 min with the combined ECF treatment for both electrodes of Fe and Al. In addition, the effect of
ECF on different water-quality parameters and the ionic interference on ECF performance and As
filtration were analyzed. The results showed the promising potential of combined ECF treatment and
filtration for treating and purifying A
پس ِجدیدت: چند غور طلب سوالات
No full textPost-modern discourse basically has been imported from France, U.K, U.S.A Urdu critic and scholars wrote some explanatory and introductory articles about it. Although the writers like Dr. Muhammad Ali Siddiqui and Imran Shahid Bhinder has raised some basic questions upon this discourse, but no critical attitude has developed about this western tradition. This article raises some basic questions about it
Enhanced Two-Stage Hierarchical Control for a Dual Mode WECS-Based Microgrid
No full textAlong with the great benefits of utilizing renewable energy (e.g., wind energy) in the power system, there are also some issues, such as increasing the uncertainty and reducing the system inertia. Communication-based centralized control has started to play a significant role in reacting to the aforementioned issues, especially for relatively small systems, such as microgrids. In this context, in this paper, an enhanced communication-based hierarchical control for a dual mode wind energy conversion system-based microgrid is modeled and investigated. The primary stage utilized the P-V/Q-f droop method, which is the preferred droop method to be used in microgrids when the line impedance is mainly resistive. The secondary stage relied on an enhanced methodology for compensating the deviations of voltage and frequency and improving the performance of the microgrid during small and large signal disturbances. Moreover, as this microgrid operates in a dual mode, the mode transition cases from grid-tied mode to autonomous mode and vice versa have been addressed. Thereafter, an improved control scheme for the unplanned outage transition and a modified control scheme for the pre-synchronization and reconnection transition were proposed. Finally, the proposed work was evaluated by the simulation results in MATLAB environment
Transient expression of synthetic coat protein gene of Cotton leaf curl Burewala virus in tobacco (Nicotiana benthamiana)
No full textIn a study conducted at National Institute for Bio-technology and Genetic Engineering (NIBGE), Faisalabad, Pakistan during 2013-14 a synthetic coat protein (CP) gene from cotton leaf curl Burewala virus was synthesized containing point mutations in its DNA sequence to escape the virus induced gene silencing problem. The synthetic CP (Syn. CP) was cloned and expressed under the control of constitutive Cauliflower mosaic virus 35S promoter. In three independent agro-inoculation experiments, Nicotiana benthamiana plants were co-inoculated with Syn. CP construct together with infectious clones of cotton leaf curl Kokhran virus (CLCu KoV) and cotton leaf curl Multan betasatellite which showed significant level for tolerance/resistance (70/30%) against typical downward leaf curl viral symptoms as compared to control plants. This observation was confirmed by PCR in which 14 out of 20 plants were positive and 6 out of 20 plants were negative for CLCuKoV detection. Southern hybridization showed a reduction level of viral DNA accumulation in 10 mild symptomatic plants out of 15 and no detection of viral DNA in 4 asymptomatic plants out of 15 indicating that Syn.CP strategy could be adopted to control CLCuD
اجتہاد الرسول ﷺ از نادیہ شریف العمری کا تعارفی مطالعہ: An Introductory Study of Ijtihad Al-Rasool ﷺ by Nadia Sharif Al-Omari
No full textThe biography of the Prophet ﷺ is a subject that has been extensively written about since the first century of Hijra, continues to be written about today, and will undoubtedly remain a topic of scholarly and devotional interest in the future. This subject holds religious, academic, historical, and contemporary significance, prompting Muslim scholars of every era to contribute to its exploration. Alongside men, women have also engaged in writing on this subject to express their devotion and love for the Prophet ﷺ. From ancient to modern times, women have played their part in this field, and while their contributions are fewer in comparison to men, their numbers are steadily increasing in modern times. Women have also explored various aspects of the Prophet's ﷺ biography in the Arabic language. One notable work in this context is "Ijtihad Al-Rasool" authored by Nadia Sharif Al-Omari. This book uniquely combines the principles of Islamic jurisprudence (Usul al-Fiqh) with the life of the Prophet ﷺ, analyzing whether the Prophet ﷺ engaged in ijtihad (independent reasoning). The author meticulously presents evidence supporting her conclusion that the Prophet ﷺ did indeed engage in ijtihad. This article provides a research-based and analytical study of her book. It begins by discussing the biographical details of the author, followed by an introduction to the book. Subsequently, the writing style of the author and the nuanced insights within her work are critically examined. Finally, the findings and recommendations of the study are presented.
Antibiotic resistance: a rundown of a global crisis
No full textBilal Aslam,1 Wei Wang,2 Muhammad Imran Arshad,3 Mohsin Khurshid,1,4 Saima Muzammil,1 Muhammad Hidayat Rasool,1 Muhammad Atif Nisar,1 Ruman Farooq Alvi,1 Muhammad Aamir Aslam,2 Muhammad Usman Qamar,1 Muhammad Khalid Farooq Salamat,5 Zulqarnain Baloch6 1Department of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan; 2NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, China; 3Institute of Microbiology, University of Agriculture Faisalabad, Faisalabad, Pakistan; 4College of Allied Health Professionals, Directorate of Medical Sciences, Government College University Faisalabad, Faisalabad, Pakistan; 5Neurobiology Division, The Roslin Institute, University of Edinburgh, Edinburgh, UK; 6College of Veterinary Medicine, South China Agricultural University, Guangzhou, China Abstract: The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial resistance has been ascribed to the misuse of these agents and due to unavailability of newer drugs attributable to exigent regulatory requirements and reduced financial inducements. Comprehensive efforts are needed to minimize the pace of resistance by studying emergent microorganisms, resistance mechanisms, and antimicrobial agents. Multidisciplinary approaches are required across health care settings as well as environment and agriculture sectors. Progressive alternate approaches including probiotics, antibodies, and vaccines have shown promising results in trials that suggest the role of these alternatives as preventive or adjunct therapies in future. Keywords: antibiotics, multidrug resistance, evolution, alternative therapie
Fatigue of woven thermoplastic composites: The effect of the fibre-matrix interface
No full textSI&CAerospace Engineerin
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