68 research outputs found
In Memory of a Friend
No full textThe article is dedicated to the memory of Rustem Sultanovich Gabyashev (1941-2010), an outstanding Kazan archeologist. He was one of the renowned experts in the Mesolithic and the Neolithic of the Volga-Kama region. The author, the researcher’s colleague and friend, narrates about his scientific and, first of all, expedition activities, offers some biographical data and characterizes his personal qualitie
Honeybee biodiversity based on five mitochondrial genes and new evidence for different sublineages in Türkiye
No full textIn this study, the genetic structure of honey bee populations in T & uuml;rkiye was analyzed using eleven restriction endonuclease enzymes targeting the COI-COII, COI, 16S rDNA, ND5 and CYT B genes. A total of 553 worker honey bee samples were collected from 43 different districts across T & uuml;rkiye, as well as from Greece, Bulgaria, and Georgia countries neighboring T & uuml;rkiye. Analysis of the COI region using the Hin fI restriction enzyme revealed the presence of two mitotypes. Type 1 was the predominant type in T & uuml;rkiye, while type 2 was detected exclusively in Hatay, a province in the southern part of the country. Notably, the absence of the HincII site in the COI region and the EcoRI site in the 16S rDNA gene in the Hatay samples suggests that these samples belong to the A lineage. However, several samples from Hatay were classified as belonging to mitochondrial lineage O due to the presence of BglII and Hin fI restriction sites in the CYT B gene. Except for Hatay, which displayed an EcoRI site in the 16S rDNA fragment and lacked a Hin fI site in the CYT B fragment, all samples were identified as belonging to the C lineage. Furthermore, the COI-COII restriction patterns with DraI for lineages C and Z were consistent with the findings. The restriction analysis revealed that several samples from Hatay exhibited the most divergent mitotype in comparison with other honey bee populations studied, resembling African or Arabian honey bees. The results of this study indicate that Anatolia serves as a genetic center for Middle Eastern honey bees, and Hatay acts as a transitional zone. However, the findings also suggest that the introduction of foreign commercial queen bees into T & uuml;rkiye has led to some degree of hybridization between native and nonnative honey bee subspecies.Dzce University Scientific Research Project Fund (DUBAP Project) [2017.05.01.531]Russian Science Foundation (RSF) [24-16-00179]This work was supported by Duezce University Scientific Research Project Fund (DUBAP Project No: 2017.05.01.531) and Russian Science Foundation (RSF) grant 24-16-00179
Balın çok yönlü biyoaktivitesi: Arılar, bitkiler ve mikroorganizmalar arasındaki etkileşimler
No full textBal, antibakteriyel, anti-enflamatuar ve antioksidan aktiviteler gibi iyi belgelenmiş faydaları ile yüzyıllardır tıbbi özellikleriyle tanınmaktadır. Bununla birlikte, balın sağlıkla ilgili amaçlarla yaygın kullanımına rağmen, biyoaktivitesinden sorumlu olan altta yatan mekanizmaların çoğu yeterince araştırılmamıştır. Bu derleme, özellikle aktif maddelere ve bal mikrobiyomunun özelliklerine katkısına odaklanarak balın bileşiminin karmaşıklığını incelemektedir. Balın çok yönlü biyoaktivitesinin arılar, bitkiler ve mikroorganizmalar arasındaki etkileşimlerden nasıl kaynaklandığını anlamadaki boşluğu doldurmayı amaçlıyoruz. Bu derleme, balın sağlığa faydalarında hayati rol oynayan hidrojen peroksit, metilglioksal, polifenoller ve antimikrobiyal peptitler gibi temel bileşiklere ışık tutmaktadır. Ayrıca, nektarın bala kimyasal dönüşümünü birlikte etkileyen ve terapötik etkinliğini artıran bal arısının bağırsak mikrobiyomunun ve nektarın mikrobiyotasının genellikle göz ardı edilen katkılarını vurgulamaktadır. Bu makale, mevcut literatürü inceleyerek, çiçek kökeni, arı alt türleri ve çevresel koşullar gibi çeşitli faktörlerin balın tıbbi kalitesini nasıl etkilediğinin daha derinlemesine araştırılması gerektiğini vurgulamaktadır. Bu mekanizmaların anlaşılması, balın tıbbi uygulamalarda en uygun şekilde kullanılmasını sağlayabilir ve yeni terapötik potansiyelleri ortaya çıkarabilir. Bu makale, balı sadece besleyici bir gıda kaynağı değil aynı zamanda güçlü bir doğal ilaç yapan karmaşık süreçler ve bileşenler hakkında kapsamlı bir inceleme sunmaktadır.Honey has been recognized for its medicinal properties for centuries, with well-documented benefits such as antibacterial, anti-inflammatory, and antioxidant activities. However, despite the widespread use of honey for health-related purposes, many of the underlying mechanisms responsible for its bioactivity remain underexplored. This review delves into the complexity of honey’s composition, particularly focusing on the active substances and the honey microbiota contribution to its properties. We aim to bridge the gap in understanding how honey’s multifaceted bioactivity arises from interactions between bees, plants, and microorganisms. The review sheds light on the key compounds, including hydrogen peroxide, methylglyoxal, polyphenols, and antimicrobial peptides, which play vital roles in honey's health benefits. It also highlights the often-overlooked contributions of the honeybee’s gut microbiota and the nectar’s microbiota, which together influence the chemical transformation of nectar into honey and enhance its therapeutic efficacy. By examining the current literature, this article emphasizes the need for deeper investigation into how various factors-such as floral origin, bee subspecies, and environmental conditions-affect the medicinal quality of honey. Understanding these mechanisms could lead to optimized use of honey in medical applications and reveal new therapeutic potentials. This article provides a comprehensive review of the intricate processes and components that make honey not only a nutritional food source but also a potent natural medicine.Russian Science Foundation (RSF) 24-16-0017
Modern methods of assessing the taxonomic affiliation of honeybee colonies
No full textAt least 30 subspecies of the honeybee Apis mellifera L. were formed allopatrically during the evolution, which spreaded throughout all Africa, Europe and West Asia. The dark forest bee Apis mellifera mellifera is the only and most valuable subspecies for the Northern and Western Europe countries, adapted to productive living in the hard-continental climate of Eurasia. In the past 100 years, natural geographical isolation of subspecies has been disrupted as a result of a human activities. Mass transportations of honeybee colonies beyond the boundaries of their area have been threatened of loss the identity of gene pool of subspecies as a result of hybridization. Preservation of the gene pool of subspecies is possible only when controlling the transportation of honeybee colonies using the methods of identification of taxonomic affiliation of honeybee colonies. Now, dozens of methods have been developed to identify the taxonomic affiliation of honeybee's colony, which are based on the variability of body parts, allozyme loci, mitochondrial DNA loci, microsatellite nuclear loci, sites of single nucleotide polymorphism (SNP). The variability of microsatellite loci and the single nucleotide polymorphism sites have shown the greatest informativeness in identification of the taxonomic affiliation of honeybee's colony.</jats:p
Co-aligning user-centered design and software engineering courses: A case study
No full textIntroducing students to different perspectives and roles in the development process allows them to engage in the work of cross-disciplinary diverse teams and even can enable them to change roles in designer-developer interactions. Industry work often places recent graduates in preexisting polarized relationship dynamics between different participants in the design and development process. This paper describes a two-stage attempt at co-alignment of software engineering and user-centered design courses: from full alignment with topic intersections and joint project to partial alignment through separate activities. We discuss challenges of both ways including time or technical constraints, increased effort from the program developers and instructors, students' and instructors' frustrations. We finalize by describing benefits of providing students with early experience identifying trade-offs between design requirements and architecture and opportunities for diverse group with different background in computer science.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Internet of Thing
Phylogenetic Uniqueness of Honeybee Apis Cerana from the Korean Peninsula Inferred from The Mitochondrial, Nuclear, and Morphological Data
No full textApis cerana is an Eastern honeybee species distributed throughout Asia and closely related to the Western honeybee species Apis mellifera distributed across all of Africa, Europe and Western Asia, and subdivided into thirty confirmed subspecies. Currently, A. cerana is an endangered bee species in contrast to A. mellifera. We sequenced and annotated the complete mitochondrial genome of A. cerana from the Jeollanam-do province of South Korea and uploaded to the DDBJ/Genbank database(AP018431). MtDNA sequence is 15.925 bp long, has 84% AT-content and 16% GC-content and contains 22 tRNA genes, 13 protein-coding genes, two ribosomal RNA genes, one AT-rich region and four non-coding intergenic regions (NC1-4). All protein-coding genes are started by ATT and ATG codons, except the genes ATP8 and ND4, which started by ATC and ATA, respectively, and are stopped by the common codons TAA and TAG. A comparative analysis of the whole mtDNA sequences of A. cerana from Korea and Taiwan, A. c. cerana from China and A. c. japonica from Japan showed that the genetic divergence of the Korean A. cerana sample from subspecies A. c. cerana (2.57%) and A. c. japonica (2.58%) matched to the level of genetic divergence of mtDNA between animal subspecies (0.8-8%). Based on the comparative analysis of complete mtDNA (~16,000 bp), two nuclear gene VG and EF1- α sequences (~8,000 bp) and morphological measurements (six parameters), we assumed that Korean A. cerana, Chinese A. c. cerana and Japanese A. c. japonica are different subspecies at an early stage of sub-speciation and could be called further as subspecies of Apis cerana koreana
Mehmed Senai: A Crimean Historian at Sarai of Khan Islam Giray »
No full textThe article is devoted to the creative work of Mehmed Senai – the Crimean chronicler at the serai of the khan Islam Geray III, as well as his chronicle “Tarih-i Islam Geray khan” (“History of the khan Islam Geray III”, 1651). The researcher gives biographical information about the author and a brief description of the source. The identity of the writer is defined and based on the text of the Preface to the Chronicle: background, education, position, religious status. The meaning of the pseudonym of Senai is under the study, the text of the chronogram in which it occurs is reproduced. Especially noted thing is the originality of the artistic structure of the Chronicle “Tarih-i Islam Geray khan”.The Chronicle “Tarih-i Islam Geray khan” is the panegyric to the Crimean khan Islam Geray whose reign represents the brilliant epoch in the history of the Crimean Khanate. The writing consists of the ceremonies of public appointments, episodes of military campaigns and making treaties, the text of khan Islam Geray’s pedigree (shejere), construction and repair of buildings.
There is the brief information about the Chronicle and about M. Senai in “Catalogue of the Turkish Manuscripts in the British Museum” (1888). The primary work on writing was conducted by Polish orientalists who prepared the edition of the original text, its translation and processing, backed with comments.
At the time of writing the Chronicle, Mehmed Senai was in his old age, he served as the kadi (religious judge). In his youth he worked as munshi (decorator of papers) in the khan’s office. He got education in the Ottoman Empire, and was engaged in the implementation of diplomatic correspondence. The prospect of identification of the author on the basis of other sources is important to clarify the hypothesis of identifying M. Senai with such Crimean Tatar author as Dzhanmuhammed.
The Chronıcle’s plot consists of the diary notes on the military expeditions, eyewitness accounts (including those of the author). The author of the work focuses the historical events of 1648–1651 covering the Crimean Tatar-Ukrainian-Polish relations. The bulk of the official documents used by Senai was narrow. Details and brevity in the coverage of events indicates that certain materials were available to the author, while others were unavailable.
The aesthetic peculiarities of the Chronicle are also notable as well as historical. The author created the vivid images of the central characters in the writing – Islam Geray, Sefer Gazi aga and Tugay bey. The work is characterized by the use of various expressive means for the purpose of idealization of the images and emotional perception of characters and events
PRE-ISLAMIC WORLD VIEWS OF THE KAZAKH PEOPLE: FROM THE END OF THE 19TH TO THE BEGINNING OF THE 21ST CENTURY
No full textThis article analyses the problems of the traditional world views and beliefs of the Kazakh people. The main purpose of the article is to show the features of such cultural phenomena as âreligious syncretismâ and âhybrid worldviewâ. The author pays attention to the cosmogonic and cosmological beliefs, the perception and feeling of place and time, religious consciousness and national identity, folk customs and traditions, cultural branding. The farming and cattle-breeding practices in the harsh climatic conditions of wide steppe spaces influenced the formation of a special type of culture and unique worldview. In the long history of the nomadic peoples who inhabited the Eurasian steppes, the history of the development of the religious worldview occupies a special place. Being in the crossroad of civilization, Central Asia has been a region of interaction between different world religious traditions, such as Zoroastrianism, Buddhism, Christianity (in their earliest forms as Nestorianism), ManiÑhaiesm, and Islam. However, the Kazakh people did not break ties with nature due to their way of life, so peopleâs beliefs and superstitions were based on the animistic, totemistic beliefs and magic. The author concludes that the cornerstone of the entire system of worldview was the faith in the opportunity to transform the world for the good of peopleâs traditions and it was reflected in the special rites, traditions, and practices
Transport Properties of Mixed-Matrix Membranes: A Kinetic Monte Carlo Study
No full textKinetic Monte Carlo (KMC) simulations are used to study transport of guest molecules in a two-phase medium in which the minority phase forms closed regions. This type of model system resembles compositions of mixed-matrix membranes (MMMs) made of a matrix and imbedded filler particles with different permeabilities. Based on an ideal filler-matrix composite morphology as defined in [H. Vinh-Thang, S. Kaliaguine, Chem. Rev. 113, 4980, 2013], the effects of the filler-particle volume fraction, particle size, shape (aspect ratio), and the spatial particle distribution on gas transport through MMMs are addressed. The results obtained for nonoverlapping and randomly placed spherical filler particles are found to be in good agreement with the analytical models available in the literature and have proven their good accuracy also for thin membranes where finite-size effects are expected to play an appreciable role. Furthermore, the prominent influence of the aspect ratio for nonspherical particles on the effective permeability is shown and scenarios are discussed where the alignment of the asymmetric filler particles give rise to anisotropic transport properties potentially favorable for the performance of MMMs. The KMC approach developed guides the optimal spatial arrangement and orientation of the filler particles for the different strategies to increase the membrane permeability and separation selectivity by transport enhancement or inhibition.ChemE/Catalysis Engineerin
Akarisit Amitraz ve Fluvalinat'ın Bal Arısı Apis mellifera'nın Üreme ve Verimliliğine Etkisi
No full textVarroa destructor is a well-known ectoparasite of the honey bee Apis mellifera. Amitraz and fluvalinate are highly effective miticides used against V. destructor infestation in colonies of honey bee A. mellifera. Though honey bees more resistant to miticides, there are side effects of these chemicals on the reproduction, olfaction, and honey production of honey bees. We showed a negative impact of miticides amitraz and fluvalinate on honey production and reproduction of honey bee colonies. Also, we assumed the reduction of olfaction of honey bees by fluvalinate due to changes of expression of olfactory related neuropeptide genes short neuropeptide F sNPF, tachykinin TK, short neuropeptide F receptor sNPFR. The external treatment of honey bee colonies by miticides amitraz and fluvalinate along with a positive effect of pest control harms reproductivity, honey productivity, and, probably, can reduce learning and memory, gustation and olfaction of honey bees. When used for a short time and with care, miticides can be less harmful to honey bees. Breeding varroa-resistant honey bees allow to reduce the use of miticides and produce organic honey. Therefore, the further development of beekeeping should be in the direction of selection for disease and Varroa resistance and adaptation to the environment.Varroa, bal arısı Apis mellifera'nın iyi bilinen bir ektoparazitidir. Amitraz ve fluvalinat, bal arısı A. mellifera kolonilerinde V. destructor istilasına karşı kullanılan oldukça yüksek etkili akarisitlerdir. Bal arıları, akarisitlere karşı daha dirençli olsalar da, bu kimyasalların bal arılarının üreme, koku alma ve bal üretimi üzerinde yan etkileri vardır. Bu çalışma ile Akarisitler olan amitraz ve fluvalinatın bal üretimi ve bal arısı kolonilerinin üremesi üzerinde olumsuz bir etkisi olduğu belirlenmiştir. Ayrıca, bal arılarının Fluvalinat’a bağlı olarak koku alma duyusunun azalması durumunu ilgili nöropeptid genlerinin kısa nöropeptid F sNPF, taşikinin TK, kısa nöropeptid F reseptörü sNPFR ifadesindeki değişiklik olduğunu varsaydık. Bal arısı kolonilerinin akarisitler olan amitraz ve fluvalinate ile kontrol edilmesi, haşere kontrolünün olumlu etkisiyle birlikte üremeye, bal verimliliğine zarar verir ve muhtemelen bal arılarının öğrenmesini ve hafızasını, lezzetini ve kokusunu muhtemelen azaltabilir. Kısa bir süre ve özenle kullanıldığında, akarisit kullanımı bal arılarına daha az zarar verebilir. Varroaya dirençli bal arılarının yetiştirilmesi, akarisit kullanımını azaltmaya ve organik bal üretmeye izin verir. Bu nedenle, arıcılığın daha da geliştirilmesi için seçim; hastalıklara, Varroa’ya dirençli ve çevreye uyum yönünde olmalıdır
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