1,726,682 research outputs found
Contribución da Biblioteca á economía do IIM
No full textPoster.-- Encontros IIM 5ª fase, Vigo, 28 de xuño de 2024N
The chemotherapic compound cisplatin causes myotube atrophy by increment of proteasoma activation.
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Noise reduction and analysis for Chang'E-1 Imaging Interferometer (IIM) data
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Imaging Interferometer (IIM) aboard Chang'E-1 is a Fourier transform imaging spectrometer, with goals to analyze the abundance and distribution of chemical elements on the lunar surface. IIM data suffer from various degradations, which will lead to misleading interpretations of IIM data and inaccuracy of subsequent applications. In this paper, we introduced a noise reduction method based on low-rank matrix decomposition theory. The restoration results are expected to have a better performance in image quality and spectral signatures according to visual and quantitative assessments. Meanwhile, we analyze the characteristic of the noise separated from IIM data using top spectral view of noise cube. The preliminary analysis of the noise characteristics contribute to optimize the data preprocessing of IIM data such as spectrum reconstruction and radiometric correction. © 2017 IEEE.</p
Contrasting Risk Profile in Idiopathic Inflammatory Myopathy (IIM) Patients with Cancer Before and After IIM Diagnosis
No full textBackground: Patients with adult-onset idiopathic inflammatory myopathy (IIM) were at risk of cancer. While the recently published international guideline on cancer screening suggested cancer risk stratification in patients with newly diagnosed IIM, the difference in clinical and serological risk profile among patients with cancer diagnosed before and after IIM diagnosis remained uncertain. Methods: MyoHK was a longitudinal observational cohort that collected data from patients with rheumatologist diagnosis of IIM from 8 rheumatology centres in Hong Kong. Data were reviewed from 2004-2023 for this study. Patients with unavailable myositis specific antibody (MSA) were excluded from analysis. Occurrence of cancer 3 years before to 3 years after the diagnosis of IIM were documented. Patients with active cancer 3 years before diagnosis of IIM were classified to “Prior cancer” group and patients with cancer diagnosed at or within 3 years after IIM diagnosis were classified to “subsequent cancer” group. Patients were stratified to high, intermediate and standard cancer risks. Risk profile between the “prior cancer” and “subsequent cancer” groups were compared. Results: 501 patients were included in analysis. 82 patients had cancer within 3 years, in which 21 patients (25.6%) had cancer within 3 years preceding IIM diagnosis and 61 patients (74.4%) developed cancer at or within 3 years after IIM diagnosis. Nasopharyngeal, lung and breast cancers accounted for the top 3 cancers in both groups. In the “Prior cancer” group, patients were more likely to be female (85.7% vs 55.7%, p = 0.014) and were MSA-negative (33.3% vs 9.8%, p = 0.011). No patient in the “Prior cancer” group developed interstitial lung disease (0% vs 18.0%, p = 0.037) or fulfilled criteria for anti-synthetase syndrome (0% vs 13.1%, p = 0.062). Anti-TIF1g antibody was the most identified MSA in the two groups (42.9% vs 54.1%, p = 374). Myositis-associated-antibody (14.3% vs 42.6%, p = 0.019) and anti-Ro52 antibody (14.3% vs 37.7%, p = 0.047) were more common in the “subsequent cancer” group. In the overall cohort, 228 (45.5%), 246 (49.1%) and 27 (5.4%) of IIM patients were stratified into high, intermediate and standard cancer risk. Two-thirds of the “Prior cancer” group were stratified into high-risk while the remaining one-third being intermediate-risk, compared to 73.8% (p = 0.532) and 26.2% (p = 0.532) in the “subsequent cancer” group. Mortality between the two groups were comparable (38.1% vs 42.6%, p = 0.716). Conclusion: Compared to IIM patients with cancer detected at or after IIM diagnosis, patients with prior cancer were more likely to be female, negative for MSA and absence for ILD
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Congenital Pseudo-myotonia in Chianina cattle
No full textThe authors present a muscle function disorder observed in 11 Chianina animals.
The clinical picture is mainly characterized by an exercise-induced muscle contracture which prevents animals from performing muscular activities more intense than a simple walk at a slow pace.
In fact, when stimulated to move faster, the muscles immediately become stiff and “freeze up” temporarily, inducing a rigid and uncoordinated gait or bunny hopping. The stiffness disappears as soon as the exercise ceases.
If the exercise is prolonged, the stiffness freezes the locomotion and the animals fall on the ground like a log. The animals do not pass out or lose consciousness as in fainting.
Retraction of the bulbi and prominence of the third eyelid are other common findings during these startle-elicited crises.
Biochemistry usually shows slightly increased levels of creatine kinase, lactate dehydrogenase, aspartate aminotransferase and L-Lactate.
Standard needle electromyography showed normal spontaneous insertion activity and voluntary electrical activity.
Routine histological preparations as well as more specific histochemical and histoenzymatic stains carried out on bioptic samples of the semimembranosus muscle failed to show any remarkable and helpful findings.
Genealogical evaluation of the affected animals revealed common ancestors which might suggest a genetic etiology.
On the basis of the clinical findings and of the scanty results obtained by collateral exams, we have adopted the term “Congenital Pseudo-myotonia”.
As regards human medicine, the disease in some way resembles the so-called “Brody’s disease”
UMP, IIM bina budaya integriti
Full text linkUNIVERSITI Malaysia Pahang (UMP) melalui Pusat Integriti dan Tadbir Urus Korporat Fakulti Pengurusan Industri (FGIC) tampil mengorak langkah bekerjasama dengan Institut Integriti Malaysia (IIM) menganjurkan program ksedaran bagi membina budaya integriti dan tadbir urus korporat dalam kalangan rakyat setempat khususnya di Pantai Timur
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