103,714 research outputs found
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
A Variable Stiffness Robotic Probe for Soft Tissue Palpation
No full textDuring abdominal palpation diagnosis, a medical practitioner would change the stiffness of their fingers in order to improve the detection of hard nodules or abnormalities in soft tissue to maximize the haptic information gain via tendons. Our recent experiments using a controllable stiffness robotic probe representing a human finger also confirmed that such stiffness control in the finger can enhance the accuracy of detecting hard nodules in soft tissue. However, the limited range of stiffness achieved by the antagonistic springs variable stiffness joint subject to size constraints made it unsuitable for a wide range of physical examination scenarios spanning from breast to abdominal examination. In this letter, we present a new robotic probe based on a variable lever mechanism able to achieve stiffness ranging from 0.64 to 1.06 N.m/rad that extends the maximum stiffness by around 16 times and the stiffness range by 33 times. This letter presents the mechanical model of the novel probe, the finite element simulation as well as experimental characterization of the stiffness response for lever actuation
Human-robot medical interaction
No full textAdvances in Soft Robotics, Haptics, AI and simulation have changed the medical robotics field, allowing robotics technologies to be deployed in medical environments. In this context, the relationship between doctors, robotics devices, and patients is fundamental, as only with the synergetic collaboration of the three parties results in medical robotics can be achieved. This workshop focuses on the use of soft robotics technologies, sensing, AI and Simulation, to further improve medical practitioner training, as well as the creation of new tools for diagnosis and healthcare through the medical interaction of humans and robots. The Robo-patient is more specifically the idea behind the creation of sensorised robotic patient with controllable organs to present a given set of physiological conditions. This is both to investigate the embodied nature of haptic interaction in physical examination, as well as the doctor-patient relationship to further improve medical practice through robotics technologies. The Robo-doctor aspect is also relevant, with robotics prototypes performing, or helping to perform, medical diagnosis. In the workshop, key technologies, as well as future views in the field, will be discussed both by expert and new upcoming researcher
Services, technologies, and systems at Ka band and beyond - A survey
No full textThis paper discusses system and technology aspects crucial to the development of satellite communications at Ka band (20-30 GHz) and beyond. It surveys the evolution of Ka band geostationary Earth orbit (GEO) satellite communications until the present stage of development of systems for direct-to-user (DTU) provision of interactive multimedia services worldwide. Then it discusses the attenuation problem and main technical issues of this new technology. Finally, it provides a view on experiments and technological developments at extremely high-frequency (EHF) band
Sensorized Phantom for Characterizing Large Area Deformation of Soft Bodies for Medical Applications
No full textRobotics is a key technology to improve and support the medical services by increasing efficiency and improving quality of care. One particular challenge is medical palpation, where a physicians uses their hands to manually feel and identify abnormalities or tumors. This is a challenging procedure that takes many years to learn. A soft robotic phantom which could provide feedback on palpation technique could enable medical professionals to learn more easily. Furthermore, this would allow quantitative information about how practitioners perform the technique to be gained. This can be used to inform and move towards robotic palpation that mirrors the human performance. In this work, we demonstrate an approach for developing a large-area sensorized phantom that uses sensor morphology to sense over a large areas. A reconstruction algorithm allows the depth of palpation to be measured and the location to be identified with a precision of ± 5mm. This phantom was used to measure deformation from human palpation, with the resultant information used to replicate the behaviour with a robot hand. To the authors' knowledge this is the first sensorized phantom that characterizes large scale deformation from human palpation to inform the performance of the procedure by a robot
Physician, patient, and caregiver experience of different wet age-related macular degeneration anti-VEGF treatment regimens in Japan: a qualitative assessment
No full textTomohiro Iida,1 Keirei Ishii2 1Department of Ophthalmology, Tokyo Women’s Medical University, Tokyo, 2Health Economics and Outcomes Research, Bayer Yakuhin Ltd., Osaka, Japan Purpose: The purpose of this study was to monitor anti-vascular endothelial growth factor (anti-VEGF) treatment regimens for wet age-related macular degeneration (wAMD) in clinical practice and to determine how they impact the physician, patient, and caregiver treatment experience. Materials and methods: This was a qualitative analysis based on semistructured interviews with 20 ophthalmologists who had practiced both pro re nata (PRN) and treat-and-extend (T&E) anti-VEGF regimens for wAMD. Interview questions were constructed to assess how the different regimens affected patient and caregiver experiences (in the opinion of the ophthalmologist) in addition to the ophthalmologist’s own experience. The interview included questions relating to 1) issues and benefits of PRN and T&E; 2) logistical and operational issues of introducing proactive therapy, especially T&E, to PRN practice; and 3) actions taken to handle the issues raised in 2). Results: A total of 18 interview results were eligible for analysis. The study demonstrated that the benefits of T&E compared with PRN included decreased burden of patient consultations, decreased patient and caregiver emotional burden, and a sustained period of macular dryness. The issues associated with T&E were increased number of injections and financial burden from prolonged treatment duration. The ophthalmologists also experienced difficulty explaining the significance of proactive injections to patients. Countermeasures to operational issues experienced by ophthalmologists varied by practice. Conclusion: Patients, caregivers, and the practicing ophthalmologists experienced benefits associated with a T&E regimen. However, in order to encourage better understanding of the T&E regimen, including its smooth implementation and significance for patients, a formal T&E treatment guideline providing standard practice should be considered. Keywords: wet age-related macular degeneration, anti-vascular growth factor, anti-VEGF as-needed, anti-VEGF treat-and-extend, wAMD patient experienc
[Dataset] Detection of DGA-based Malware Communications from DoH Traffic Using Machine Learning Analysis
No full textDoH-DGA-Malware-Traffic-HKD (csv_files.zip, l3-malware.csv, pcap_files.zip, and README.txt):
If you use the dataset, please be sure to cite the following paper.Rikima Mitsuhashi, Yong Jin, Katsuyoshi Iida, Takahiro Shinagawa, and Yoshiaki Takai,"Detection of DGA-based Malware Communications from DoH Traffic Using Machine Learning Analysis,"2023 IEEE 20th Consumer Communications & Networking Conference (CCNC), 2023.https://ieeexplore.ieee.org/document/10059835CIRA-CIC-DoHBrw-2020-and-DoH-DGA-Malware-Traffic-HKD.zip:
If you use the dataset, please be sure to cite the following papers because the dataset has data from the CIRA-CIC-DoHBrw-2020 [1] and DoH-DGA-Malware-Traffic-HKD [2] datasets.
Mohammadreza MontazeriShatoori, Logan Davidson, Gurdip Kaur, and Arash Habibi Lashkari,"Detection of DoH Tunnels using Time-series Classification of Encrypted Traffic,"The 5th IEEE Cyber Science and Technology Congress, Calgary, Canada, August 2020. https://ieeexplore.ieee.org/document/9251211
Rikima Mitsuhashi, Yong Jin, Katsuyoshi Iida, Takahiro Shinagawa, and Yoshiaki Takai,"Detection of DGA-based Malware Communications from DoH Traffic Using Machine Learning Analysis,"2023 IEEE 20th Consumer Communications & Networking Conference (CCNC), 2023.https://ieeexplore.ieee.org/document/10059835References:
[1] CIRA-CIC-DoHBrw-2020 (https://www.unb.ca/cic/datasets/dohbrw-2020.html)
[2] DoH-DGA-Malware-Traffic-HKD (https://github.com/rikima-mitsuhashi/DoH-DGA-Malware-Traffic-HKD/)Updates:
README.txt and CIRA-CIC-DoHBrw-2020-and-DoH-DGA-Malware-Traffic-HKD.zip were added on March 27, 2023
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
Full text linkIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
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